is caffeine an narcotic

Butalbital, acetaminophen, caffeine, and codeine phosphate capsule is a combination drug product intended as a treatment for tension headache. Butalbital, acetaminophen, caffeine, and codeine phosphate capsule consists of a fixed combination of butalbital 50 mg, acetaminophen 325 mg and caffeine 40 mg. The role each component plays in the relief of the complex of symptoms known as tension headache is incompletely understood.

DESCRIPTION

"butalbital, acetaminophen, caffeine, and codeine phosphate ( Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate ) capsule [Qualitest Pharmaceuticals]CIIIRx only DESCRIPTIONButalbital, acetaminophen, caffeine, and codeine phosphate is supplied in capsule form for oral administration. Each capsule contains:codeine phosphate, USP ...........................................30 mgbutalbital, USP ..........................................................50 mgcaffeine, USP ............................................................40 mgacetaminophen, USP ...............................................325 mg Codeine phosphate [7,8-Didehydro-4,5α–epoxy-3-methoxy-17-methylmorphinan-6α- ol phosphate (1:1) (salt) hemihydrate.

C 18 H 24 NO 7 P, anhydrous mw 397.37], is a narcotic analgesic and antitussive. Butalbital (5-allyl-5-isobutylbarbituric acid, C 11 H 16 N 2 O 3, mw 224.26), is a short- to intermediate-acting barbiturate. Caffeine (1,3,7-trimethylxanthine, C 8 H 10 N 4 O 2, mw 194.19), is a central nervous system stimulant.

Acetaminophen (4'-hydroxyacetanilide, C 8 H 9 NO 2, mw 151.16), is a non-opiate, non-salicylate analgesic and antipyretic. Active Ingredients: codeine phosphate, USP, butalbital, USP, caffeine, USP, and acetaminophen, USP. Inactive Ingredients: black iron oxide, colloidal silicon dioxide, FD&C Blue #1, gelatin, magnesium stearate, pregelatinized corn starch, sodium lauryl sulfate, and titanium dioxide CLINICAL PHARMACOLOGY

Pharmacokinetics The behavior of the individual components is described below. Codeine Codeine is readily absorbed from the gastrointestinal tract. It is rapidly distributed from the intravascular spaces to the various body tissues, with preferential uptake by parenchymatous organs such as the liver, spleen and kidney.

Codeine crosses the blood-brain barrier, and is found in fetal tissue and breast milk. The plasma concentration does not correlate with brain concentration or relief of pain; however, codeine is not bound to plasma proteins and does not accumulate in body tissues.

The plasma half-life is about 2.9 hours. The elimination of codeine is primarily via the kidneys, and about 90% of an oral dose is excreted by the kidneys within 24 hours of dosing. The urinary secretion products consist of free and glucuronide conjugated codeine (about 70%), free and conjugated norcodeine (about 10%), free and conjugated morphine (about 10%), normorphine (4%), and hydrocodone (1%).

The remainder of the dose is excreted in the feces. At therapeutic doses, the analgesic effect reaches a peak within 2 hours and persists between 4 and 6 hours. See OVERDOSAGE for toxicity information. Butalbital Butalbital is well absorbed from the gastrointestinal tract and is expected to distribute to most tissues in the body.

Barbiturates in general may appear in breast milk and readily cross the placental barrier. They are bound to plasma and tissue proteins to a varying degree and binding increases directly as a function of lipid solubility.

Elimination of butalbital is primarily via the kidney (59% – 88% of the dose) as unchanged drug or metabolites. The plasma half-life is about 35 hours. Urinary excretion products include parent drug (about 3.6% of the dose), 5-isobutyl-5- (2,3-dihydroxypropyl) barbituric acid (about 24% of the dose), 5-allyl-5 (3-hydroxy-2-methyl-1-propyl) barbituric acid (about 4.8% of the dose), products with the barbituric acid ring hydrolyzed with excretion of urea (about 14% of the dose), as well as unidentified materials.

Of the material excreted in the urine, 32% is conjugated. The in vitro plasma protein binding of butalbital is 45% over the concentration range of 0.5-20 mcg/m L. This falls within the range of plasma protein binding (20% – 45%) reported with other barbiturates such as phenobarbital, pentobarbital, and secobarbital sodium.

The plasma-to-blood concentration ratio was almost unity indicating that there is no preferential distribution of butalbital into either plasma or blood cells. See OVERDOSAGE for toxicity information. Caffeine Like most xanthines, caffeine is rapidly absorbed and distributed in all body tissues and fluids, including the CNS, fetal tissues, and breast milk. Caffeine is cleared through metabolism and excretion in the urine. The plasma half-life is about 3 hours.

Hepatic biotransformation prior to excretion results in about equal amounts of 1-methylxanthine and 1-methyluric acid. Of the 70% of the dose that is recovered in the urine, only 3% is unchanged drug. See OVERDOSAGE for toxicity information. Acetaminophen Acetaminophen is rapidly absorbed from the gastrointestinal tract and is distributed throughout most body tissues.

The plasma half-life is 1.25 – 3 hours, but may be increased by liver damage and following overdosage. Elimination of acetaminophen is principally by liver metabolism (conjugation) and subsequent renal excretion of metabolites.

Approximately 85% of an oral dose appears in the urine within 24 hours of administration, most as the glucuronide conjugate, with small amounts of other conjugates and unchanged drug.

See OVERDOSAGE for toxicity information. INDICATIONS AND USAGEButalbital, acetaminophen, caffeine, and codeine phosphate capsule is indicated for the relief of the symptom complex of tension (or muscle contraction) headache. Evidence supporting the efficacy and safety of butalbital, acetaminophen, caffeine, and codeine phosphate capsule in the treatment of multiple recurrent headaches is unavailable. Caution in this regard is required because codeine and butalbital are habit-forming and potentially abusable.

CONTRAINDICATIONSThis combination product is contraindicated under the following conditions:– Hypersensitivity or intolerance to acetaminophen, caffeine, butalbital, or codeine.– Patients with porphyria.

WARNINGSIn the presence of head injury or other intracranial lesions, the respiratory depressant effects of codeine and other narcotics may be markedly enhanced, as well as their capacity for elevating cerebrospinal fluid pressure. Narcotics also produce other CNS depressant effects, such as drowsiness, that may further obscure the clinical course of the patients with head injuries.

Codeine or other narcotics may obscure signs on which to judge the diagnosis or clinical course of patients with acute abdominal conditions. Butalbital and codeine are both habit-forming and potentially abusable. Consequently, the extended use of butalbital, acetaminophen, caffeine, and codeine phosphate capsule is not recommended.

PRECAUTIONSGeneral Butalbital, acetaminophen, caffeine, and codeine phosphate capsule should be prescribed with caution in certain special-risk patients such as the elderly or debilitated, and those with severe impairment of renal or hepatic function, head injuries, elevated intracranial pressure, acute abdominal conditions, hypothyroidism, urethral stricture, Addison's disease, or prostatic hypertrophy. Ultra-Rapid Metabolizers of Codeine Some individuals may be ultra-rapid metabolizers due to a specific CYP2D6*2x2 genotype.

These individuals convert codeine into its active metabolite, morphine, more rapidly and completely than other people. This rapid conversion results in higher-than-expected serum morphine levels. Even at labeled dosage regimens, individuals who are ultra-rapid metabolizers may experience overdose symptoms such as extreme sleepiness, confusion, or shallow breathing.

The prevalence of this CYP2D6 phenotype varies widely and has been estimated at 0.5 to 1% in Chinese and Japanese, 0.5 to 1% in Hispanics, 1–10% in Caucasians, 3% in African Americans, and 16–28% in North Africans, Ethiopians and Arabs.

Data is not available for other ethnic groups. When physicians prescribe codeine-containing drugs, they should choose the lowest effective dose for the shortest period of time and should inform their patients about these risks and the signs of morphine overdose (see PRECAUTIONS - Nursing Mothers ).

Information for Patients Butalbital, acetaminophen, caffeine, and codeine phosphate capsule may impair mental and/or physical abilities required for the performance of potentially hazardous tasks such as driving a car or operating machinery. Such tasks should be avoided while taking butalbital, acetaminophen, caffeine, and codeine phosphate capsule.

Alcohol and other CNS depressants may produce an additive CNS depression, when taken with butalbital, acetaminophen, caffeine, and codeine phosphate capsule, and should be avoided.

Codeine and butalbital may be habit-forming. Patients should take the drug only for as long as it is prescribed, in the amounts prescribed, and no more frequently than prescribed. For information on use in geriatric patients, see PRECAUTIONS/Geriatric Use. Caution patients that some people have a variation in a liver enzyme and change codeine into morphine more rapidly and completely than other people.

These people are ultra-rapid metabolizers and are more likely to have higher-than-normal levels of morphine in their blood after taking codeine which can result in overdose symptoms such as extreme sleepiness, confusion, or shallow breathing. In most cases, it is unknown if someone is an ultra-rapid codeine metabolizer. Nursing mothers taking codeine can also have higher morphine levels in their breast milk if they are ultra-rapid metabolizers.

These higher levels of morphine in breast milk may lead to life-threatening or fatal side effects in nursing babies.

Instruct nursing mothers to watch for signs of morphine toxicity in their infants including increased sleepiness (more than usual), difficulty breastfeeding, breathing difficulties, or limpness. Instruct nursing mothers to talk to the baby's doctor immediately if they notice these signs and, if they cannot reach the doctor right away, to take the baby to an emergency room or call 911 (or local emergency services).

Laboratory Tests In patients with severe hepatic or renal disease, effects of therapy should be monitored with serial liver and/or renal function tests. Drug Interactions The CNS effects of butalbital may be enhanced by monoamine oxidase (MAO) inhibitors.

Butalbital, acetaminophen, caffeine, and codeine phosphate capsule may enhance the effects of:– Other narcotic analgesics, alcohol, general anesthetics, tranquilizers such as chlordiazepoxide, sedative-hypnotics, or other CNS depressants, causing increased CNS depression. Drug/Laboratory Test Interactions Codeine Codeine may increase serum amylase levels. Acetaminophen Acetaminophen may produce false-positive test results for urinary 5-hydroxy-indoleacetic acid. Carcinogenesis, Mutagenesis, Impairment of Fertility No adequate studies have been conducted in animals to determine whether acetaminophen, codeine and butalbital have a potential for carcinogenesis or mutagenesis.

No adequate studies have been conducted in animals to determine whether acetaminophen and butalbital have a potential for impairment of fertility. Pregnancy Teratogenic Effects Pregnancy Category C: Animal reproduction studies have not been conducted with butalbital, acetaminophen, caffeine, and codeine phosphate capsule. It is also not known whether butalbital, acetaminophen, caffeine, and codeine phosphate capsule can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity.

Butalbital, acetaminophen, caffeine, and codeine phosphate capsule should be given to a pregnant woman only when clearly needed. Nonteratogenic Effects Withdrawal seizures were reported in a two-day-old male infant whose mother had taken a butalbital-containing drug during the last 2 months of pregnancy.

Butalbital was found in the infant's serum. The infant was given phenobarbital 5 mg/kg, which was tapered without further seizure or other withdrawal symptoms. Labor and Delivery Use of codeine during labor may lead to respiratory depression in the neonate. Nursing Mothers Caffeine, butalbital and acetaminophen is excreted in breast milk in small amounts, but the significance of its effects on nursing infants is not known.

Because of the potential for serious adverse reactions in nursing infants from Caffeine, butalbital and acetaminophen, a decision should be made whether to discontinue the drug, taking into account the importance of the drug to the mother. Codeine is secreted into human milk. In women with normal codeine metabolism (normal CYP2D6 activity), the amount of codeine secreted into human milk is low and dose-dependent.

Despite the common use of codeine products to manage postpartum pain, reports of adverse events in infants are rare. However, some women are ultra-rapid metabolizers of codeine. These women achieve higher-than-expected serum levels of codeine's active metabolite, morphine, leading to higher-than-expected levels of morphine in breast milk and potentially dangerously high serum morphine levels in their breastfed infants.

Therefore, maternal use of codeine can potentially lead to serious adverse reactions, including death, in nursing infants. The prevalence of this CYP2D6 phenotype varies widely and has been estimated at 0.5 to 1% in Chinese and Japanese, 0.5 to 1% in Hispanics, 1–10% in Caucasians, 3% in African Americans, and 16–28% in North Africans, Ethiopians and Arabs.

Data is not available for other ethnic groups. The risk of infant exposure to codeine and morphine through breast milk should be weighed against the benefits of breastfeeding for both the mother and baby. Caution should be exercised when codeine is administered to a nursing woman. If a codeine-containing product is selected, the lowest dose should be prescribed for the shortest period of time to achieve the desired clinical effect.

Mothers using codeine should be informed about when to seek immediate medical care and how to identify the signs and symptoms of neonatal toxicity, such as drowsiness or sedation, difficulty breastfeeding, breathing difficulties, and decreased tone, in their baby.

Nursing mothers who are ultra-rapid metabolizers may also experience overdose symptoms such as extreme sleepiness, confusion, or shallow breathing. Prescribers should closely monitor mother-infant pairs and notify treating pediatricians about the use of codeine during breastfeeding (see PRECAUTIONS – General - Ultra-Rapid Metabolizers of Codeine).

Pediatric Use Safety and effectiveness in pediatric patients have not been established. Geriatric Use Clinical studies of butalbital, acetaminophen, caffeine, and codeine phosphate capsules did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Other reported clinical experience has not identified differences in responses between the elderly and younger patients.

In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.

Butalbital is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function.

Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function. ADVERSE REACTIONSFrequently Observed The most frequently reported adverse reactions are drowsiness, lightheadedness, dizziness, sedation, shortness of breath, nausea, vomiting, abdominal pain, and intoxicated feeling.

Infrequently Observed All adverse events tabulated below are classified as infrequent. Central Nervous: headache, shaky feeling, tingling, agitation, fainting, fatigue, heavy eyelids, high energy, hot spells, numbness, sluggishness, seizure. Mental confusion, excitement or depression can also occur due to intolerance, particularly in elderly or debilitated patients, or due to overdosage of butalbital. Autonomic Nervous: dry mouth, hyperhidrosis. Gastrointestinal: difficulty swallowing, heartburn, flatulence, constipation. Cardiovascular: tachycardia. Musculoskeletal: leg pain, muscle fatigue. Genitourinary: diuresis.

Miscellaneous: pruritus, fever, earache, nasal congestion, tinnitus, euphoria, allergic reactions. The following adverse reactions have been voluntarily reported as temporally associated with a related product containing aspirin, butalbital, caffeine, and codeine. Central Nervous: abuse, addiction, anxiety, disorientation, hallucination, hyperactivity, insomnia, libido decrease, nervousness, neuropathy, psychosis, sexual activity increase, slurred speech, twitching, unconsciousness, vertigo.

Autonomic Nervous: epistaxis, flushing, miosis, salivation. Gastrointestinal: anorexia, appetite increased, diarrhea, esophagitis, gastro-enteritis, gastrointestinal spasms, hiccup, mouth burning, pyloric ulcer. Cardiovascular: chest pain, hypotensive reaction, palpitations, syncope. Skin: erythema, erythema multiforme, exfoliative dermatitis, hives, rash, toxic epidermal necrolysis.

Urinary: kidney impairment, urinary difficulty. Miscellaneous: allergic reaction, anaphylactic shock, cholangiocarcinoma, drug interaction with erythromycin (stomach upset), edema. The following adverse drug events may be borne in mind as potential effects of the components of butalbital, acetaminophen, caffeine, and codeine phosphate capsule. Potential effects of high dosage are listed in the OVERDOSAGE section. Acetaminophen: allergic reactions, rash, thrombocytopenia, agranulocytosis.

Caffeine: cardiac stimulation, irritability, tremor, dependence, nephrotoxicity, hyperglycemia. Codeine: nausea, vomiting, drowsiness, lightheadedness, constipation, pruritus. Several cases of dermatological reactions, including toxic epidermal necrolysis and erythema multiforme, have been reported for butalbital, acetaminophen, and caffeine tablets. DRUG ABUSE AND DEPENDENCEControlled Substance Butalbital, acetaminophen, caffeine, and codeine phosphate capsule is controlled by the Drug Enforcement Administration and is classified under Schedule III. Abuse and Dependence Codeine Codeine can produce drug dependence of the morphine type and, therefore, has the potential for being abused.

Psychological dependence, physical dependence, and tolerance may develop upon repeated administration, and it should be prescribed and administered with the same degree of caution appropriate to the use of other oral narcotic medications. Butalbital Barbiturates may be habit-forming: Tolerance, psychological dependence, and physical dependence may occur especially following prolonged use of high doses of barbiturates.

The average daily dose for the barbiturate addict is usually about 1,500 mg. As tolerance to barbiturates develops, the amount needed to maintain the same level of intoxication increases; tolerance to a fatal dosage, however, does not increase more than twofold.

As this occurs, the margin between an intoxication dosage and fatal dosage becomes smaller. The lethal dose of a barbiturate is far less if alcohol is also ingested. Major withdrawal symptoms (convulsions and delirium) may occur within 16 hours and last up to 5 days after abrupt cessation of these drugs. Intensity of withdrawal symptoms gradually declines over a period of approximately 15 days. Treatment of barbiturate dependence consists of cautious and gradual withdrawal of the drug.

Barbiturate-dependent patients can be withdrawn by using a number of different withdrawal regimens. One method involves initiating treatment at the patient's regular dosage level and gradually decreasing the daily dosage as tolerated by the patient. OVERDOSAGEFollowing an acute overdosage of butalbital, acetaminophen, caffeine, and codeine phosphate capsule, toxicity may result from the barbiturate, the codeine, or the acetaminophen.

Toxicity due to the caffeine is less likely, due to the relatively small amounts in this formulation. Signs and Symptoms Toxicity from barbiturate poisoning include drowsiness, confusion, and coma; respiratory depression; hypotension; and hypovolemic shock.

Toxicity from codeine poisoning includes the opioid triad of: pinpoint pupils, depression of respiration, and loss of consciousness. Convulsions may occur. In acetaminophen overdosage: dose-dependent, potentially fatal hepatic necrosis is the most serious adverse effect. Renal tubular necroses, hypoglycemic coma, and thrombocytopenia may also occur. Early symptoms following a potentially hepatotoxic overdose may include: nausea, vomiting, diaphoresis, and general malaise.

Clinical and laboratory evidence of hepatic toxicity may not be apparent until 48–72 hours post-ingestion. In adults hepatic toxicity has rarely been reported with acute overdoses of less than 10 grams, or fatalities with less than 15 grams. Acute caffeine poisoning may cause insomnia, restlessness, tremor, and delirium, tachycardia, and extrasystoles. Treatment A single or multiple overdose with butalbital, acetaminophen, caffeine, and codeine phosphate capsule is a potentially lethal polydrug overdose, and consultation with a regional poison control center is recommended. Immediate treatment includes support of cardiorespiratory function and measures to reduce drug absorption.

Vomiting should be induced mechanically, or with syrup of ipecac, if the patient is alert (adequate pharyngeal and laryngeal reflexes). Oral activated charcoal (1 g/kg) should follow gastric emptying. The first dose should be accompanied by an appropriate cathartic.

If repeated doses are used, the cathartic might be included with alternate doses as required. Hypotension is usually hypovolemic and should respond to fluids. The value of vasopressor agents such as Norepinephrine or Phenylephrine Hydrochloride in treating hypotension is questionable since they increase vasoconstriction and decrease blood flow. However, if prolonged support of blood pressure is required, Norepinephrine Bitartrate (Levophed®)* may be given I. V. with the usual precautions and serial blood pressure monitoring.

A cuffed endotracheal tube should be inserted before gastric lavage of the unconscious patient and, when necessary, to provide assisted respiration. If renal function is normal, forced diuresis may aid in the elimination of the barbiturate. Alkalinization of the urine increases renal excretion of some barbiturates, especially phenobarbital.

Meticulous attention should be given to maintaining adequate pulmonary ventilation. In severe cases of intoxication, peritoneal dialysis, or preferably hemodialysis may be considered. If hypoprothrombinemia occurs due to acetaminophen overdose, vitamin K should be administered intravenously. Naloxone, a narcotic antagonist, can reverse respiratory depression and coma associated with opioid overdose.

Naloxone 0.4–2 mg is given parenterally. Since the duration of action of codeine may exceed that of the naloxone, the patient should be kept under continuous surveillance and repeated doses of the antagonist should be administered as needed to maintain adequate respiration.

A narcotic antagonist should not be administered in the absence of clinically significant respiratory or cardiovascular depression. If the dose of acetaminophen may have exceeded 140 mg/kg, N-acetyl-cysteine should be administered as early as possible. Serum acetaminophen levels should be obtained, since levels 4 or more hours following ingestion help predict acetaminophen toxicity.

Do not await acetaminophen assay results before initiating treatment. Hepatic enzymes should be obtained initially, and repeated at 24-hour intervals. Methemoglobinemia over 30% should be treated with methylene blue by slow intravenous administration. Toxic Doses (for adults)Butalbital:toxic dose 1 g (20 capsules of butalbital, acetaminophen, caffeine, and codeine phosphate capsule)Acetaminophen:toxic dose 10 g (30 capsules of butalbital, acetaminophen, caffeine, and codeine phosphate capsule)Caffeine:toxic dose 1 g (25 capsules of butalbital, acetaminophen, caffeine, and codeine phosphate capsule)Codeine:toxic dose 240 mg (8 capsules of butalbital, acetaminophen, caffeine, and codeine phosphate capsule)DOSAGE AND ADMINISTRATIONOne or 2 capsules every 4 hours.

Total daily dosage should not exceed 6 capsules. Extended and repeated use of this product is not recommended because of the potential for physical dependence. HOW SUPPLIEDButalbital, acetaminophen, caffeine, and codeine phosphate capsules Light blue opaque cap with a grey, opaque body. Cap is imprinted in black with ""V"". Body is imprinted with ""3109"" in black. Bottles of 10, 100, and 1000.

Store and Dispense At 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature]; in a tight, light-resistant container as defined in the USP.

*Levophed is a registered Trademark of Sanofi Winthrop Pharmaceuticals. Manufactured for: QUALITEST PHARMACEUTICALS Huntsville, AL 358118181579 R11/07-R3Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate (Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate)PRODUCT INFOProduct Code 0603-2553 Dosage Form CAPSULERoute Of Administration ORAL DEA Schedule CIIIINGREDIENTSName (Active Moiety) Type Strengthcodeine phosphate (codeine) Active 30 MILLIGRAM In 1 CAPSULEbutalbital (butalbital) Active 50 MILLIGRAM In 1 CAPSULEcaffeine (caffeine) Active 40 MILLIGRAM In 1 CAPSULEacetaminophen (acetaminophen) Active 325 MILLIGRAM In 1 CAPSULEblack iron oxide Inactivesilicon dioxide Inactive FD&C Blue #1 Inactivegelatin Inactivemagnesium stearate Inactivepregelatinized corn starch Inactivesodium lauryl sulfate Inactivetitanium dioxide Inactive IMPRINT INFORMATIONCharacteristic Appearance Characteristic Appearance Color blue (light blue opaque) , gray (grey opaque) Score 1Shape CAPSULE Symbol false Imprint Code V;3109 Coating false Size 22mm PACKAGING# NDC Package Description Multilevel Packaging1 0603-2553-10 10 CAPSULE In 1 BOTTLE, PLASTIC None2 0603-2553-21 100 CAPSULE In 1 BOTTLE, PLASTIC None3 0603-2553-32 1000 CAPSULE In 1 BOTTLE, PLASTIC None Revised: 01/2008 Qualitest Pharmaceuticals "

Butalbital and acetaminophen combination may also be used for other kinds of headaches or other kinds of pain as determined by your doctor. These medicines are available only with your doctor's prescription.

Description and Brand Names

Description and Brand Names Drug information provided by: Micromedex US Brand Name Anolor 300Cephadyn Dolgic LQEsgic Esgic-Plus Ezol Fioricet Geone Margesic Orbivan CFPhrenilin Phrenilin Forte Descriptions Butalbital and acetaminophen combination is a pain reliever and relaxant.

It is used to treat tension headaches. Butalbital belongs to the group of medicines called barbiturates. Barbiturates act in the central nervous system (CNS) to produce their effects. When you take butalbital for a long time, your body may get used to it so that larger amounts are needed to produce the same effects.

This is called tolerance to the medicine. Also, butalbital may become habit-forming (causing mental or physical dependence) when it is used for a long time or in large doses.

Physical dependence may lead to withdrawal side effects when you stop taking the medicine. In patients who get headaches, the first symptom of withdrawal may be new (rebound) headaches. Some butalbital and acetaminophen combinations also contain caffeine. Caffeine may help to relieve headaches. However, caffeine can also cause physical dependence when it is used for a long time. This may lead to withdrawal (rebound) headaches when you stop taking it.

This product is available in the following dosage forms: Tablet Capsule Solution Before Using Portions of this document last updated: March 01, 2017Copyright © 2018 Truven Health Analytics Inc. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Share Tweet

An opioid is sometimes called a narcotic. The combination of aspirin, butalbital, caffeine, and codeine is used to treat tension headaches. This medicine is not for treating headaches that come and go. This medication may also be used for purposes not listed in this medication guide.

Fiorinal with Codeine

Fiorinal with Codeine Patient Information Including Side Effects A Visual Guide to Migraine Headaches Slideshow Headache and Migraine Triggers Slideshow Take the Headaches Quiz Brand Names: Ascomp with Codeine, Fiorinal with Codeine Generic Name: aspirin, butalbital, caffeine, and codeine (Pronunciation: AS pir in, bue TAL bi tal, KAF een, and KOE deen)What is aspirin, butalbital, caffeine, and codeine (Ascomp with Codeine, Fiorinal with Codeine)?

What are the possible side effects of this medication (Ascomp with Codeine, Fiorinal with Codeine)? What is the most important information I should know about this medication (Ascomp with Codeine, Fiorinal with Codeine)?

What should I discuss with my healthcare provider before taking this medication (Ascomp with Codeine, Fiorinal with Codeine)? How should I take this medication (Ascomp with Codeine, Fiorinal with Codeine)? What happens if I miss a dose (Ascomp with Codeine, Fiorinal with Codeine)?

What happens if I overdose (Ascomp with Codeine, Fiorinal with Codeine)? What should I avoid while taking this medication (Ascomp with Codeine, Fiorinal with Codeine)? What other drugs will affect aspirin, butalbital, caffeine, and codeine (Ascomp with Codeine, Fiorinal with Codeine)? Where can I get more information? What is aspirin, butalbital, caffeine, and codeine (Ascomp with Codeine, Fiorinal with Codeine)?

Aspirin is a salicylate (sa-LIS-il-ate). It works by reducing substances in the body that cause pain, fever, and inflammation. Butalbital is a barbiturate. It relaxes muscle contractions involved in a tension headache. Caffeine is a central nervous system stimulant. It relaxes muscle contractions in blood vessels to improve blood flow. Codeine is an opioid pain medication.

What are the possible side effects of this medication (Ascomp with Codeine, Fiorinal with Codeine)? Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have a serious side effect such as:shallow breathing, slow heart rate;fast or pounding heart rate, muscle twitching;confusion, unusual thoughts or behavior;bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;problems with urination; ornausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). Less serious side effects include:feeling dizzy, shaky, anxious, or agitated;heartburn, mild nausea, vomiting, upset stomach, constipation, diarrhea;mood changes, sleep problems (insomnia);sweating, urinating more than usual; orringing in your ears, blurred vision, or dry mouth.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about this medication (Ascomp with Codeine, Fiorinal with Codeine)? Aspirin should not be given to a child or teenager who has a fever, especially if the child also has flu symptoms or chicken pox.

Aspirin can cause a serious and sometimes fatal condition called Reye's syndrome in children. Stop using this medication and call your doctor at once if you have any symptoms of bleeding in your stomach or intestines. Symptoms include black, bloody, or tarry stools, and coughing up blood or vomit that looks like coffee grounds.

Codeine and butalbital may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it. Fiorinal with Codeine Patient Information including How Should I Take A Visual Guide to Migraine Headaches Slideshow Headache and Migraine Triggers Slideshow Take the Headaches Quiz What should I discuss with my healthcare provider before taking this medication (Ascomp with Codeine, Fiorinal with Codeine)?

You should not use this medication if you are allergic to aspirin, butalbital, caffeine, or codeine, or if you have:porphyria;stomach ulcer;a bleeding or blood clotting disorder; oran allergy to an NSAID (non-steroidal anti-inflammatory drug) such as Advil, Motrin, Aleve, Celebrex, Orudis, Indocin, Lodine, Voltaren, Toradol, Mobic, Relafen, Feldene, and others.

To make sure you can safely take aspirin, butalbital, caffeine, and codeine, tell your doctor if you have any of these other conditions:liver or kidney disease;asthma or other breathing disorders;a history of head injury or brain tumor;a history of heart attack, stroke, blood clot, or stomach ulcers;low blood pressure;a stomach or intestinal disorder;curvature of the spine; ormental illness, or a history of drug or alcohol addiction. Codeine and butalbital may be habit forming and should be used only by the person for whom it was prescribed. Never share this medication with another person, especially someone with a history of drug abuse or addiction.

Keep the medication in a place where others cannot get to it. FDA pregnancy category C. Codeine and butalbital may cause addiction or withdrawal symptoms in a newborn if the mother takes the medication during pregnancy. Taking aspirin during late pregnancy may cause bleeding in the mother or the baby during delivery.

Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Codeine can pass into breast milk and may harm a nursing baby. The use of codeine by some nursing mothers may lead to life-threatening side effects in the baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Aspirin should not be given to a child or teenager who has a fever, especially if the child also has flu symptoms or chicken pox.

Aspirin can cause a serious and sometimes fatal condition called Reye's syndrome in children. How should I take this medication (Ascomp with Codeine, Fiorinal with Codeine)? Take exactly as prescribed. Never take this medication in larger amounts, or for longer than recommended by your doctor.

Follow the directions on your prescription label. Tell your doctor if the medicine seems to stop working as well in relieving your pain. Do not stop using this medication suddenly after long-term use, or you could have unpleasant withdrawal symptoms.

Ask your doctor how to avoid withdrawal symptoms when you stop using aspirin, butalbital, caffeine, and codeine. If you need surgery, tell the surgeon ahead of time that you are using this medication. You may need to stop using the medicine for a short time.

Store at room temperature away from moisture and heat. Keep track of the amount of medicine used from each new bottle. Codeine is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Fiorinal with Codeine Patient Information including If I Miss a Dose A Visual Guide to Migraine Headaches Slideshow Headache and Migraine Triggers Slideshow Take the Headaches Quiz What happens if I miss a dose (Ascomp with Codeine, Fiorinal with Codeine)?

Since this medication is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose (Ascomp with Codeine, Fiorinal with Codeine)? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

An overdose of codeine can be fatal. Overdose symptoms may include extreme drowsiness or insomnia, restless feeling, tremors, fast heart rate, pinpoint pupils, nausea, vomiting, dark urine, jaundice (yellowing of the skin or eyes), confusion, ringing in your ears, fainting, weak pulse, seizure (convulsions), blue lips, shallow breathing, or no breathing.

What should I avoid while taking this medication (Ascomp with Codeine, Fiorinal with Codeine)? This medication may impair your thinking or reactions. Avoid driving or operating machinery until you know how the medicine will affect you. Ask a doctor or pharmacist before using any cough, cold, allergy, or pain medication.

Aspirin and caffeine are contained in many combination medicines. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains aspirin or caffeine. Avoid drinking alcohol. It may increase your risk of stomach bleeding. What other drugs will affect aspirin, butalbital, caffeine, and codeine (Ascomp with Codeine, Fiorinal with Codeine)?

Before using this medication, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety).

They can add to sleepiness caused by butalbital or codeine. Tell your doctor about all other medicines you use, especially:bupropion (Wellbutrin, Zyban);ciprofloxacin (Cipro);insulin or oral diabetes medication;naloxone (Narcan, Suboxone);atropine (Atreza, Sal-Tropine), belladonna (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), or scopolamine (Transderm Scop);another salicylate such as Nuprin Backache Caplet, Kaopectate, Knee Relief, Pamprin Cramp Formula, Pepto-Bismol, Tricosal, Trilisate, and others;bladder or urinary medicines such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare);a blood thinner such as rivaroxaban (Xarelto), warfarin (Coumadin, Jantoven);bowel cleansing preparations (Half Lytely, Fleet Prep Kit, Evac-Q-Kwik, Go Lytely, Supraprep, and others);bronchodilators such as ipratropium (Atrovent) or tiotropium (Spiriva);diet pills, caffeine pills, or other stimulants (such as ADHD medications);irritable bowel medicines such as dicyclomine (Bentyl), hyoscyamine (Hyomax), or propantheline (Pro Banthine);an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate);an NSAID such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others;steroids (such as prednisone); orulcer medications such as glycopyrrolate (Robinul) or mepenzolate (Cantil).

This list is not complete and other drugs may interact with aspirin, butalbital, caffeine, and codeine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Where can I get more information? Your pharmacist can provide more information about aspirin, butalbital, caffeine, and codeine.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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This combination medication is used to treat tension headaches. Aspirin helps to decrease the pain from the headache. Caffeine helps increase the effects of aspirin. Butalbital is a sedative that helps to decrease anxiety and cause sleepiness and relaxation.

Fiorinal

Drugs & Medications Fiorinal GENERIC NAME (S): Butalbital-Aspirin-Caffeine Read Reviews (84)Uses Uses

How to use Fiorinal Take this medication by mouth, usually every 4 hours as needed or as directed by your doctor. Do not take more than 6 capsules/tablets in a 24-hour period. Take with a full glass of water (8 ounces or 240 milliliters) unless your doctor directs you otherwise.

Do not lie down for at least 10 minutes after taking this medication. To help prevent stomach upset, take it with food or milk. The dosage is based on your medical condition and response to therapy. This medication works best if it is used as the first signs of a headache occur. If you wait until the headache has worsened, the medication may not work as well. This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses.

In such cases, withdrawal symptoms (such as nausea / vomiting, mental/mood changes, seizures) may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details, and report any withdrawal reactions right away.

Though it helps many people, this medication may sometimes cause addiction. This risk may be higher if you have a substance use disorder (such as overuse of or addiction to drugs/alcohol). Do not increase your dose, take it more often, or use it for a longer time than prescribed. Use the smallest effective dose.

Properly stop the medication when so directed. Inform your doctor if you notice increased use of this medication, a worsening of headaches, an increase in the number of headaches, the medication not working as well, or use of this medication for more than 2 headache episodes a week.

Your doctor may need to change your medication and/or add a separate medication to prevent the headaches. Related Links What conditions does Fiorinal treat? Side Effects Precautions Interactions Overdose Images More Resources for Fiorinal oral Check Interactions Read Reviews (84)

Butalbital addiction treatment is necessary when a person shows signs and symptoms of a dependency on butalbital. Butalbital is the generic name given to certain medications that combine butalbital with acetaminophen or aspirin and caffeine to treat chronic pain and migraine headaches.

Butalbital Addiction Treatment

Butalbital Addiction Treatment Article Summary Detox Treatment: Methods of Detoxification and Options for Help Rehab and Recovery One-on-One Counseling Behavioral and Cognitive-Behavioral Therapy Family and Group Therapy

When used for short-term treatment of pain, withdrawal symptoms are often minor and short lived, but barbiturates can be habit forming; with long-term use, patients may build a tolerance to the drug, as well as a psychological and physical dependence.

This means that more butalbital is needed to have the same effect, and the withdrawal symptoms become more severe as use continues. Did You Know? Butalbital is a barbiturate that is FDA approved and is often prescribed by physicians, but the active ingredients are addictive. Butalbital is a highly addictive barbiturate, both physically and psychologically. The necessity of butalbital addiction treatment is determined by medical professionals, based on the presence of a number warning signs.

These red flags may appear in several forms, but butalbital addiction symptoms typically will include at least one of the following: Lying to doctors about pain or headache severity to convince them to prescribe a higher dose of butalbital Mixing butalbital with alcohol or other drugs to achieve a better “high”Taking more butalbital than prescribed or using the drug more frequently than is recommended by your physician While the above signs are key indicators that butalbital addiction treatment may be needed, they are often visible only to the user.

There are other symptoms caused by the psychological addiction to butalbital that are often visible to those around the user as well. These are primarily behavioral in nature and are similar to symptoms of addiction to other drugs, gambling, sex or alcohol.

Psychological signs of butalbital addiction may include one or more of the following: Isolation Mood swings Inexplicable hostility or aggression Secretive behavior or lying Stealing or borrowing money or medication from other butalbital users Detox Abruptly stopping the use of butalbital-containing medications results in a variety of withdrawal symptoms.

These withdrawal symptoms typically occur within eight to 36 hours of the last dose of medication, and last up to seven days.

They typically include at least one of the following: Elevated body temperature Increased blood pressure Increased heart and respiratory rates Delirium Nausea and/or vomiting Tremors Ringing in the ears Difficulty breathing Fatigue Raised consciousness Anxiety or nervousness Disorientation Severe headache Although rare, more serious withdrawal symptoms can include abnormal vital signs and seizures. Withdrawal symptoms and signs typically decrease in severity within about two weeks. Butalbital addiction treatment in a medically-supervised setting is often necessary during detoxification to manage symptoms and prevent medical complications.

Did you know? Butalbital is the generic name for a drug called Fiorinal, and it has been around since the 1920s, when it was discovered that combining aspirin, caffeine and butalbital produced a short-acting, effective sedative. Treatment: Methods of Detoxification and Options for Help Withdrawing from butalbital is a necessary part of the detoxification process. Symptoms can be intense, because many detoxification treatment methods require that the patient stop using butalbital drugs entirely to rid the body of its effects as rapidly as possible.

Successful detoxification is vital to long-term recovery from butalbital addiction and is best achieved in a medically supervised environment.

There are several butalbital addiction treatment options available for safely and comfortably withdrawing from butalbital, but these can be narrowed down to three basic methods. Gradual Detox Inpatient/Residential Rapid Drug Detox Gradual Detox In some programs, the withdrawal and detoxification process is careful and gradual.

For example, the patient is given the regular dosage of the drug for a brief amount of time, and then this dosage is decreased daily to minimize the withdrawal symptoms.

Withdrawal symptoms can be treated in an outpatient program with the use of benzodiazepines or phenobarbital, but regular medical supervision by your physician or a treatment facility is critical to success. Sponsor Crestview Recovery6025 SE Belmont St Portland, Oregon 97215Sponsor Summit Detox3330 N Federal Hwy Boynton Beach, Florida 33435Sponsor Sabino Recovery8505 E. Ocotillo Drive Tucson, Arizona 85750Sponsor Oxford Treatment Center297 CR 244Etta, Mississippi 38627Rehab and Recovery As with many addiction treatment programs, rehab and recovery are recommended after detoxing.

Rehab and recovery can begin in many different settings, including a medical outpatient clinic with counseling services and group support or a private or public-funded inpatient rehab facility. The benefit of an inpatient facility is that the patient receives around-the-clock care and support to ensure a successful recovery from butalbital addiction. This treatment option depends largely on the patient’s situation and whether other commitments, such as a job, allow for inpatient care. Did you know? Butalbital is a short-acting drug that is related to the longer-acting phenobarbital. Both medications are prescribed to treat migraine and tension headaches, but when used daily, they are habit forming.

Following detox, an effective butalbital addiction treatment program will shift the focus from the physical withdrawal symptoms to the psychological issues faced by the patient. A butalbital rehab program that is carried out in an inpatient drug rehab center often has the best success rate.

Typically, these programs should last at least 90 days and help the patient develop healthier ways of dealing with life and the pressures that accompany it.

Often, the combination of an inpatient “sober living” facility, followed by an inpatient or outpatient butalbital addiction recovery program, is necessary to making a successful transition back into regular life.

Depending on your location, you may have several different options for butalbital addiction rehab and recovery, but most of these programs can be separated into two categories: inpatient and outpatient care in a private or publicly funded facility. Inpatient butalbital addiction treatment is highly effective because patients are given constant medical care and treatment for both their psychological and physical addictions. Outpatient butalbital addiction treatment provides care in a rehab facility, but the patient does not remain there around the clock.

In most cases, patients visit the facility daily or weekly but reside at home for the duration of treatment. This may be an effective butalbital addiction treatment option in later stages of butalbital rehab, but it may not be effective in the early days of recovery. An effective butalbital rehabilitation program removes butalbital from your body and from your surroundings.

It should also provide treatment for the patterns of behavior and the emotional issues surrounding the addiction. In most butalbital addiction treatment facilities, various forms of counseling are provided to achieve this treatment. One-on-One Counseling Individual or one-on-one counseling focuses on the emotional issues that may have contributed to the butalbital addiction. This is done in a private and secure environment, with only a therapist or counselor and the patient present.

Individual therapy is most helpful when there is a co-occurring mental disorder such as anxiety or depression. This type of counseling also provides the patient a chance to privately voice concerns he or she may not be comfortable sharing with anyone other than a trained counselor or psychiatrist.

In an inpatient butalbital addiction treatment facility, patients often have daily access to a counselor, if necessary. This may be scaled back as the patient moves through the butalbital addiction treatment program and becomes less dependent on the support given by individual counseling.

Behavioral and Cognitive-Behavioral Therapy In many inpatient butalbital addiction treatment programs, successful rehab includes behavioral therapy that focuses on eliminating unhealthy behaviors by replacing them with better, healthier ones. This type of therapy utilizes rewards like positive reinforcement, along with rehearsals that help the patient achieve long-term recovery outside of the treatment facility.

Cognitive-behavioral therapy teaches new behavioral patterns as well, but the focus targets the motivations and emotions behind the addiction rather than the physical actions.

This type of butalbital addiction treatment therapy attempts to change or modify the thought processes that led to the addiction or abuse. Family and Group Therapy Butalbital addiction treatment often requires that family and/or friends undergo therapy along with the patient to ensure a successful recovery from butalbital addiction. Family members commonly form habits that enable the butalbital abuse in order to cope with the patient’s addiction. Family counseling sessions help family members rebuild relationships and focus on healthy behaviors and interactions that do not include enabling.

Group therapy provides patients a safe and private setting where they are able to discuss and then work on their personal addiction issues with peers who share an understanding of what they are going through.

Group therapy sessions are usually supervised by a qualified counselor or therapist, which helps patients realize they are not alone. Group counseling provides each patient the opportunity to share experiences and worries with other patients who are also undergoing butalbital addiction treatment.

Group counseling typically occurs at least once a week in the initial stages of butalbital rehab, and the frequency may be scaled back to monthly meetings later in the butalbital addiction treatment program.

Drug Rehab Centers Drug rehab centers offer individuals suffering from a drug- or alcohol-related dependency and withdrawal symptoms a place to get help and regain control of their lives. There are many types of rehabilitation centers, each offering specialized treatment and different rehabilitation programs.

Read More No matter which type of butalbital addiction rehab facility you choose, it is vital to long-term recovery that some form of counseling is provided. In most butalbital addiction treatment programs, it is recommended that the patient utilize a combination of group therapy and one-on-one counseling. Both group counseling and one-on-one counseling programs encourage honesty from the patient and provide a solid support system for the patient.

They also share the goal of ensuring long-term recovery from butalbital addiction. Group and one-on-one counseling are often combined in butalbital addiction treatment programs to provide the patient with the most support possible during rehab. The type of butalbital addiction treatment program required will depend on the severity and duration of the addiction.

The facility will typically evaluate the individual’s situation and then determine the best butalbital addiction treatment for the patient’s unique circumstances. The most effective butalbital rehab option may involve seeking a private inpatient facility. Private rehab centers are not free, but they offer a high quality of care, just as you’ll find with a public medical facility; however, private rehab facilities can often offer a more private, secluded setting.

Both public and private butalbital addiction treatment programs offer qualified medical supervision and support during the rehab process, but the additional privacy offered by a private facility can be beneficial for patients who wish to keep knowledge of their rehab and recovery limited to their immediate family and friends.

The first step to long-term recovery is contacting someone for information on how to begin rehabilitation. If you or someone you know is addicted to or has developed a dependency on butalbital, call us toll free at 1-888-287-0471 Who Answers? to discuss available butalbital addiction treatment options. Calls are confidential, and the lines are open 24 hours a day, seven days a week. You can also click here to contact us by email for more information. Return to Top

I know that both drugs have the same dose of active barbiturate; butalbital, both my mother and my father have one or the other. My mother is given Fioricet for migrains, and my dad is given Fiorinal because he has a blood platelet issue and aspirin would not be advisable for him to take due to increased bleeding risk.

Thread: Butalbital (the barbiturate in Fioricet) Information

"Butalbital (the barbiturate in Fioricet) Information#1tablehead Bluelighter Join Date Sep 2007Posts 62210-08-2009 13:17I always wondered what fioricet is like at recreational doses. I have a friend who is prescribed them for headaches and would willingly give me some to munch on. Soo i was wondering what the high is like and if its even worth it?? Ive heard they are like benzos but i have also heard they give wayy more euphoria.

But then again that person might have been talkin bout the big gun barbituates... I dont remember.

I searched and found no answer. So gimme loads of input#2pallidamors Bluelighter Join Date Sep 2008Location Bankailorado Posts 7,23410-08-2009 15:04I'm not really sure what a recreational dose of butalbital is considered...i've always considered it one of the less fun barbs (versus sodium barbital and secobarbital, the other ones i've tried ya know?)

but I've definitely popped a few fioricet on occasion. Zero euphoria, some lethargy, but all in all I was kind of bored most of the time I was on them.

Not even watching CNN and thinking about the liberal run media cheered me up. Maybe I always popped them in the wrong state of mind (as in, during opiate withdrawal with the hopes of getting some sleep), but I was underwhelmed at worst, and just moderately whelmed at best with fioricet.#3Eagleman Bluelighter Join Date Mar 2009Location Midwest USAPosts 65810-08-2009 15:37You have to take a lot of butalbital to catch a barb buzz.

When you do it just impairs you like alcohol, no ""incredible euphoria"" like you are hoping for. Be careful as it contains APAP, so don't take too much of a drug that's not really worth it.#4Too many doses Bluelight Crew Join Date Jul 2008Location Gainesville, Florida Posts 4,49610-08-2009 15:46It ain't a good high I'll tell you that#5|>R ()|)!G/-\|_Bluelighter Join Date Jun 2007Posts 1,20410-08-2009 16:37They gave it to my daughter when she had her tonsils out.

She lost a fair amount of coordination, looked pretty relaxed, and generally ""out of it"".#6purple_cloud Bluelight Crew Join Date Jul 2009Location NYCPosts 3,68310-08-2009 16:46Fioricet is useless if you ask me...

I was prescribed them for headaches. They make me feel really...strange, I can't explain it. But it's far from pleasant...and when I took over the recommended dose, in an attempt to get high off of them... I had the same ""I feel relaxed and tired but thanks to the caffeine my legs keep moving everytime I try to fall asleep"" thing going on.

I tried to give them away and none of my druggie friends even wanted them --- so IMO, fioricet = total crap, and really don't help out migraines too much at all either.#7Opiate Fiend OCGreenlighter Join Date Aug 2009Location Where the hills roll and the pills flow Posts 3914-03-2010 21:51I know this is an old thread but I happened across it and the misinformation, or should I say, incomplete information bothered me.

So this is my understanding, FTR (for the record). From what I understand about Butalbital (contained in fioricet, fiorinal, etc.)

and my experiences with it ... I find it pretty enjoyable. This is coming from a guy who was taking multiple Oxy Contin 20s and oxycodone 10/325s a day before I got clean using Suboxone (suboxone/naloxone). The two highs are nothing alike, because butalbital is sort of like an older-generation benzodiazepine (think alprazolam, lorazepam, clonazepam).

Butalbital (from hereon called butal) is part of a class of drugs known as barbiturates, which were popular in the 60s and early 70s but are rarely prescribed anymore except by older docs and for special purposes (mainly tension headaches in the case of Fioricet) because they've been replaced by the newer-class benzos and z-class (zaleplon, zolpidem, and zopiclone) drugs (z-class drugs are actually in different class than bezos). Oxy Contin (time-released oxycodone without the APAP (search APAP if you don't know what I'm talking about)) is an opiate analgesic.

For a new-b, about 3 butalbitals is the place to start for recreation. Be aware, though, that butal is often paired with either acetaminophen or aspirin (and sometimes even codeine) so the common cautions with APAP (paracetamol) apply and an extraction method is needed if your getting above the 1.3 gram (at once) range (unless you're doing these daily and then 1.3 grams (at once) daily isn't even really safe when it comes to APAP (again search APAP for more info)).

One Fioricet, for example, contains 50 mg butalbital, 325 mgs of APAP in the form of acetaminophen and 40 mgs of caffiene. If you do take opiates, be aware a synergistic effect exists between drugs in the opiate class and barbiturates. That's not necessarily a bad thing, but be aware because the combination can cause respiratory depression. Anywho. For me (in my subjective opinion) butal can cause intense body highs and benzo-type feeling. I often hear people say it's like being drunk but that is not entirely correct. The term ""wallbangers"" were applied to barbiturates by older barb-users ""back in the day"" for this reason.

Unlike benzos, however, my memory isn't affected as badly by butal and I always remember my entire care-free experiences. I experience an intense body-buzz. Because of the caffeine I am often energized throughout the experience and can complete a number of tasks like cleaning, etc.

IMO butal is certainly worth trying at least once or twice and should not be written off entirely just because a few people don't get anything out of it (who knows if they even took enough or if they didn't have high tolerances to stronger barbs).

As an interesting aside I would note that while butalbital is listed as a Schedule III drug under the United States Controlled Substances Act, when it is compounded with APAP and caffeine that status is eliminated. Fioricet, for example, is not considered a controlled substance. Fiorinal (which traditionally in the U. S. contains aspirin in place of acetaminophen) is, however, scheduled.

Some formulations in the U. S. contain codeine as an additional ingredient in the butalbital, acetaminophen and caffeine mix or butalbital, aspirin and caffeine mix. For those worried about caffeine making them jittery I will say that I had the same worry applied to me (for some reason I'm extremely sensitive to caffeine but could handle a barrage of narcotics).

The butalbital canceled it out of me. To ease your worry, if you start with three Fioricets as I noted then you shouldn't really have to worry, as the caffeine is equivalent to the amount in a cup of coffee. Anywho, that is my spiel on the subject of butalbital-containing products. As always, practice safety and become informed about any substance you're planning to put into your body. p.s. My apologies to the mods, again, for digging up this old post. Last edited by Opiate Fiend OC; 15-03-2010 at 00:10 .#8Captain.

Heroin Senior Moderator Sober Living Words Join Date Nov 2008Location My hopes are blighted, my heart is broken, my life a burden, everything around me is sad and mournful; earth has become distasteful to me, and human voices distract me.

It is mercy to let me die, for if I live I shall lose my reason and become mad. Posts 63,42915-03-2010 01:23""What's this drug like"" threads go to BDD.| Sober Living |#9shmeglyn Bluelighter Join Date May 2008Posts 17715-03-2010 22:12imo worthless and at even slightly higher doses for me make me sick.... it can come with and without codiene.

works for headaches but recreationally crap#10oldman51Greenlighter Join Date Feb 2009Location mo. Posts 1416-03-2010 20:11Take it with soma and it's a good high#11cmeloni81Bluelighter Join Date Mar 2010Posts 4816-03-2010 21:46Shit is no fun at all#12Pillthrill Bluelighter Join Date Dec 2007Location USAPosts 11,20416-03-2010 21:48You can take up to 6 pills and still be safe.

I found the high a LITTLE like Tramadol. Speedy from the caffeine and sedating from the downers. Although recreationally it isn't much.#13Cloud_9Bluelighter Join Date Dec 2006Location Ganymede orbitting Jupiter Posts 57516-03-2010 22:07Originally Posted by Eagleman You have to take a lot of butalbital to catch a barb buzz.

When you do it just impairs you like alcohol, no ""incredible euphoria"" like you are hoping for. Be careful as it contains APAP, so don't take too much of a drug that's not really worth it. This is pretty much correct, and with barbiturates having a much slimmer safety index than benzodiazepines do. You could take 5 one day and be able to catch a nice nap and the next day you take 6 and you take a permanent nap! In my experience a butalbital ""high"" is more or less similar to being drunk except you don't inherit the inebriated frame of mind which alcohol is loved for.

Butalbital, the three or four times I have seriously tried to use it for something more than just zapping a headache was not anything distinctly pleasurable.

Sure, it could make you trip all over yourself and struggle to walk the line, but not being able to control your body without much in the way of mental inebriation sounds more like something I would avoid if at all possible, and these couple of times I used butalbital compounds in anything more than a therapeutic amount was either to knock myself out during a particularly difficult methadone withdrawal, and the first time more as an experiment.

Needless to say, I was thoroughly underwhelmed.#14K'd-OUT-in-AZBluelighter Join Date Jul 2008Location Somewhere between Eden and North Utopia. Somewhere beneath the astral plain Posts 5,95917-03-2010 00:14No incredible euphoria but 6 capsules will produce a nice but subtle light headed, floaty, relaxed feeling. I wouldn't pin it as a ""recreational drug"" but when your just looking to chill out its a worth while drug to take. It goes nicely with Soma.#15Cloud_9Bluelighter Join Date Dec 2006Location Ganymede orbitting Jupiter Posts 57517-03-2010 00:50Originally Posted by K'd-OUT-in-AZNo incredible euphoria but 6 capsules will produce a nice but subtle light headed, floaty, relaxed feeling.

I wouldn't pin it as a ""recreational drug"" but when your just looking to chill out its a worth while drug to take. It goes nicely with Soma. I'd be careful about stating a dosage in the ever ambiguous unit of ""capsules"" as there are a couple different preparations that I know of that contain butalbital: there is Fioricet, and there is Fiorinal.

I am not sure whether or not they have a different amount of butalbital per tablet/capsule but I would still recommend if a user is going to abuse these that he find out exactly what dosages he is using and what an acceptable dosing window is.#16K'd-OUT-in-AZBluelighter Join Date Jul 2008Location Somewhere between Eden and North Utopia.

Somewhere beneath the astral plain Posts 5,95917-03-2010 16:08Originally Posted by Cloud_9I'd be careful about stating a dosage in the ever ambiguous unit of ""capsules"" as there are a couple different preparations that I know of that contain butalbital: there is Fioricet, and there is Fiorinal.

I am not sure whether or not they have a different amount of butalbital per tablet/capsule but I would still recommend if a user is going to abuse these that he find out exactly what dosages he is using and what an acceptable dosing window is.

Fiorinal and Fioricet both contain the same dosage; 50mg of butalbital. Only difference is Fiorinal contains aspirin while Fioricet contains acetaminophen. Both of which shouldn't exceed 6 capsules/tablets. I wouldn't recommend dosages unless I knew the correct knowledge. I've been prescribed both drugs plenty of times in the past.#17Cloud_9Bluelighter Join Date Dec 2006Location Ganymede orbitting Jupiter Posts 57502-04-2010 01:04Originally Posted by K'd-OUT-in-AZFiorinal and Fioricet both contain the same dosage; 50mg of butalbital.

Only difference is Fiorinal contains aspirin while Fioricet contains acetaminophen. Both of which shouldn't exceed 6 capsules/tablets. I wouldn't recommend dosages unless I knew the correct knowledge. I've been prescribed both drugs plenty of times in the past.

I know that both drugs have the same dose of active barbiturate; butalbital, both my mother and my father have one or the other. My mother is given Fioricet for migrains, and my dad is given Fiorinal because he has a blood platelet issue and aspirin would not be advisable for him to take due to increased bleeding risk.

I just wished to advise any person who might read this thread to exercise caution and look up what a recommended ""recreational"" dose would be and if in doubt to venture on the low end. I usually take about 4-8 tablets of Fioricet and will filter the acetaminophen out of a preparation of 20 tablets if I get a refill and keep the solution on hand because I mainly like to use the active ingredient when I have a migraine when I wish nothing more to curl up into a ball in a dark place and pass the fuck out.

Also, exercise caution when combining with alcohol! Barbiturates and other sedatives mixed with even a couple drinks could possibly be a fatal mistake and at very least make one hell of a raging black-out a distinct possibility.

I had no idea...#18angelinaz Greenlighter Join Date Oct 2010Location USAPosts 228-10-2010 09:08Ok...call me an idiot, but I had no idea that the medicine I use for my head aches are used to get high...and that my favorite way of using them is actually really dangerous!

I started taking generic fioricet like 3 yrs ago when my migraines started. But since then I've found that they are great for making a hang-over never happen!!!

Here's a little history... I take 40mg of Adderall XR each morning and 20-30mg of Dextroamphetamine 2x's a day for my narcolepsy. Well, when I'm gonna be going out for a night of partying, I always take a 30mg dose of my Dex before heading out and drinking so I don't get sleepy, and never get sloppy drunk...then around 2AM, (after drinking quite a lot) and the night is coming to an end, I take 2 of my fioricets with whatever is left of the vodka and cranberry in my hand during last call,lol...

I always eat after drinking because I have a really fast metabolism, and end up feeling like shit if I dont!!! Is taking the fioricet while drinking that harmful, even if it's only 2, and I eat a lot after???? I really hate to lose my morning after head ache prevention pill!lol#19vacathizzle Bluelighter Join Date Feb 2008Location California Posts 27528-10-2010 16:09Don't mix fioricet with alcohol.

I did and I ended up in the hospital for 3 days with a tube coming out of my dick. I threw up the charcoal they pumped my stomach with, and it got underneath all the tape they used to secure all my tubes, and the charcoal stained my skin for weeks.

Not to mention it tastes fucking gross. I had been out drinking, probably had 5 beers total, then took 4 fioricet which was normal for me before bedtime if i really needed sleep... woke up in an ambulence 2 days later, was hospitalized for another day after that, then let go.

I was off balance and uncoordinated for several days after. Fioricet is NOT worth it.#20Stay Sedated Bluelighter Join Date Aug 2010Location In the future Posts 2,63828-10-2010 19:09barb highs are similar to alcohol and benzos, although butalbital isn't a ""good"" barb and not as fun as secobarbital or phentobarbital (which is hard to find these days).

butalbital is better than phenobarbital though.#21Psychedelic Jay Bluelighter Join Date Jun 2009Location Houston, Texas Posts 5,99228-10-2010 21:51It takes a gram of butalbital to be lethal. It is o.k. to only surpass 2000mg of acetaminophen. You can get fucked up on these. You can do a CWE and there will be nothing left but acetaminophen and butalbital. This will let you enjoy butalbital for what it is worth. It's o.k. not the best high IMO. 200 mg of butalbital is a good dose to be high.#22lasthurrah19Bluelighter Join Date Apr 2009Location South FLPosts 57628-10-2010 22:00Yeah, these will fuck you up.

A few years ago my friend would get random scripts for back pain, the obv didn't want to give him anything heavy... this is when I first tried out fioricet and tramadol, stuff like that. I got the spins real bad the first time I took these. I probably took 4-6, honestly I have no clue anymore. After that, no spins. It was similar to benzos + some kind of body high, somewhat similar to hydrocodone but not nearly as strong.

It's a different high for sure, but I didn't have to wonder if they were recreational or not. I also met a girl at a half way house I lived at whose DOC was butalbital.

I don't know how you can keep that habit up with the tolerance I'm sure you get, but nevertheless.#23Psychedelic Jay Bluelighter Join Date Jun 2009Location Houston, Texas Posts 5,99228-10-2010 22:05Originally Posted by lasthurrah19...

I also met a girl at a half way house I lived at whose DOC was butalbital. I don't know how you can keep that habit up with the tolerance I'm sure you get, but nevertheless.

You will run into trouble eventually with the acetaminophen.#24T. Calderone Moderator Basic Drug Discussion Homeless & Anonymous Join Date Aug 2010Posts 8,08928-10-2010 22:06My doctor used to prescribe them for my cluster headaches back in the early 90's.

I never took more than 2 in one day and they were relaxing. Never got really buzzed from them though.#25Stay Sedated Bluelighter Join Date Aug 2010Location In the future Posts 2,63828-10-2010 22:14Originally Posted by lasthurrah19. It was similar to benzos + some kind of body high, somewhat similar to hydrocodone but not nearly as strong.

It's a different high for sure, but I didn't have to wonder if they were recreational or not. really? i'd compare butalbital more to alcohol intoxication than an opiate like hydrocodone. but it does feel like a ""hypnotic"" benzo like flunitrazepam or temazepam, just with less euphoria and slightly more clumbsiness. idk about a ""body high"" though. i find barbs like butalbital and phenobarbital less ""fun"" than strong benzos, but a godsend for stimulant comedowns or periods of bad insomnia. "

The caffeine doesn't necessarily make the analgesic effects of aspirin more powerful, but it does speed up the relief; caffeine speeds up the heart rate and blood flow, which serves to ferry aspirin throughout the system at a faster rate. Aspirin and caffeine are also combined for use as a weight loss supplement.

What are the Effects of Taking Aspirin and Caffeine Together?

When combined, aspirin and caffeine can act as an enhanced pain reliever.

Ephedrine, caffeine and aspirin (ECA) stacks have long been used in exercise routines. ECA stacks are sometimes packaged and marketed for sale by nutrition companies, although that practice has declined as ECA stacks have come under suspicion for causing heart attacks, strokes and other health problems. Aspirin and caffeine have long been used together as a method for relieving pain. In fact, some companies that manufacture analgesics use caffeine in their products.

For example, acetaminophen, a medication use for pain relief and fever reduction, is often combined with caffeine to form an even more effective analgesic. Many medications marketed as headache remedies have both caffeine and aspirin as ingredients as well. Although it's generally safe to take aspirin and caffeine for pain relief, caution should be exercised. Consuming alcohol while ingesting pain relievers, for example, can be severely damaging to the liver, and may result in other adverse reactions.

Overconsumption can cause stomach ulcers as well. Pregnant women also are often advised to steer clear of taking such substances, both for the mother's and the baby's health.

Aspirin has also been linked to the development of Reyes Syndrome in children and teens; individuals in those age brackets should seek out other options for pain management. Consuming aspirin and caffeine together also may result in weight loss. For example, ECA stacks, which often are used for weight loss and weight lifting exercises, contain both ingredients and can help burn fat and increase athletic stamina, but at a serious risk; nutrition products containing ephedrine have been linked to heart problems, strokes and other life-threatening conditions.

For public safety, many places throughout the world have banned the sale of ECA products — in the U. S., Canada and Europe, sales of such products have been limited or curtailed altogether.

Many people experience allergic reactions to aspirin or caffeine, or both. The severity of allergic reactions can vary.

The most severe reactions can result in difficult breathing, hives, swelling and loss of consciousness. Caffeine and aspirin also can have negative interactions with other medications and even herbal supplements and vitamins. For such reasons, it's advised to consult a personal doctor before taking any product containing these substances.

Ad You might also Like Recommended Related wise GEEK Articles What Are the Different Types of Aspirin Products? What Is Involved in the Metabolism of Aspirin? What Are the Effects of Combining Ephedrine and Caffeine? What Are the Risks of Mixing Alcohol and Aspirin? What is the Connection Between Caffeine and Pain? What are Prostaglandin Inhibitors? What is Salicylamide? Ad Discuss this Articleanon953457Post 4Caffeine increases blood flow, not decrease.

Aspirin does thin the blood, and when combined with caffeine it flows at a pretty good rate! I work a incredibly physical job in a warehouse (walking 25 miles daily, loading thousands of cases weighing 1lb-85lbs each onto pallets all day) and caffeine and aspirin are almost mandatory for us!candyquilt Post 3Caffeine and aspirin is a great alternative to more expensive OTC pain relievers. I take them together for migraines.bear78Post 2@ysmina-- That might be the effect of caffeine alone, but when taken with aspirin, the effects are different.

Caffeine makes our heart beat faster which means that blood flows throughout the body at a faster rate. Aspirin is not just a pain reliever, but also a blood thinner. So when someone takes aspirin with caffeine, the pain reliever circulates through the body very quickly.

This is why many people take an aspirin followed by a cup of coffee after a hangover. It relieves headaches very quickly.

The downside is that caffeine is diuretic and will expel water from the body through urine. So if you take aspirin and caffeine together, you need to drink plenty of water toview entire post Related Topics Career Opportunities In Human Resource Management Human Resource Management Human Resource Manager Job Description Human Resource Management Jobs Human Resources Management Consultingysmina Post 1I'm confused about aspirin and caffeine.

I did not know that caffeine increases blood flow. As far as I know, caffeine makes blood vessels shrink and reduces blood flow. This is why caffeine is suggested for migraines, because it reduces blood flow to the brain and reduce the pain that is felt. Caffeine is even included in some migraine medications for this reason. So I'm doubtful about caffeine making aspiring effective faster. Post your comments Post Anonymously Loginusernamepasswordforgot password? Registerusernamepasswordconfirmemail

Fioricet is acetaminophen (hence the cet at the end), caffiene and butalbital which is a mild barbiturate. They are used for tension and migraine headaches. Some do have codeine in them-it would be a fioricet with codeine or fioricet #3. They do not have percocet in them! If they screen for barbiturates it might show or if they are the kind with codeine they may show. If you have a script you shouldnt have to worry.

Will fioricet show up on a urine drug screen?

Home › Q & A › Questions › Will fioricet show up on a... Will fioricet show up on a urine drug screen?

Asked 5 Apr 2011 by ltdsbaby Updated 6 Jun 2013Topics fioricet, drug test, urine test Answer this Question Report Favorite Responses (4)Sort NE New York Guy44 5 Apr 2011. It is used to relieve tension headaches and ids prescribed for other ting, It Contains Acetaminophen, Butalbital, and Caffeine.

I was told that some drugs like Fioricet have opiates in them, so if they do show up on a Drug test it would mean it does have some sort of an opiate, And I remember my aunt used to take them along with my Mother for her migraines, and I remember her telling me that Fioricet contained a little bit of Percocet, and Barbiturate's in it.

And as far as I know, they don't check for barbiturates on a state drug test, they are really only looking for Cocaine, Heroin, PCP, MDMA, and Crystal Meth.

I am not really sure about the Phenobarbital coming up in a regular state drug test, so you shouldn't have anything to worry about.

So Good Luck and I Hope I was Helpful. New Yorkguy44, Hope I was Helpful. Votes: +0 Comment Vote up Report NE New York Guy44 6 Apr 2011Hey , I'm Sorry I was confusing the drug called Fiorinal, with Fiorocet. Usually Fiorinal has Codeine in it, not Percocet. And Same thing as Fiorocet, unless you were taking it without the Codeine.

If that's the case the yeah, Codeine will ome uo in your drug test as an opiate/ But I have taken many State Drug tests, when I was on Probation, and like I said they only look for hard Drugs, like Dope, Coke, PCP, or Meth, or Pot.

But you should be good as far as the Barbiturates go. Good Luck. New York Guy44. DZ Dzoo Baby 6 Apr 2011Fiorinal and Fioricet are basically the same thing except fiorinal has aspirin and fioricet has acetaminophen!View all 3 comments Add your Comment DZ Dzoo Baby 5 Apr 2011New york Guy is partially right.

Otherwise it will depend on what they are looking for in the screen. Votes: +0 Comment Vote up Report CH Chucks_Angel 13 Jan 2012Yes.

I know first hand. I am prescribed Fioricet and have taken tests and I had to have my Dr fax my script to the screening place to verify. It's because of the butalbital. It will cause you to fail. Most doctors warn patients of this when prescribed to them.

At least nine did. If its not your script, I wouldn't take them. Votes: +0 Comment Vote up Report IN Infolady 1 Feb 2013YES, YES, YES.

Regular Fioracet WILL show up on a urine drug test. My friend was fired from his job for testing positive THREE days after taking 2 capsules one time without a prescription!Votes: +0 Comment Vote up Report Add your Answer Find similar questions Further Information Fioricet Information for Consumers Fioricet Information for Healthcare Professionals (includes dosage details)Side Effects of Fioricet (detailed)Search for questions Still looking for answers?

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Acetaminophen, butalbital, and caffeine, are used together in an oral preparation to treat pain, specifically headaches. Acetaminophen is a non-narcotic analgesic for pain and headache relief. Butalbital is a barbiturate used for its sedative effects.

"Description

Caffeine is found in many analgesic formulations and may be beneficial in Migraine and vascular headaches. Fioricet is also available with codeine. The combination of acetaminophen and codeine produces a greater analgesic effect than that produced by acetaminophen alone or by higher doses of opiate. Also, this combination might cause fewer adverse reactions than do equianalgesic doses of either agent alone. Before Using This Medicine In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do.

This is a decision you and your doctor will make. For frovatriptan, the following should be considered: Allergies- Be certain to tell your doctor if you have ever had any unusual or allergic reaction to butalbital or other barbiturates, or to acetaminophen, aspirin, or caffeine. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy- FDA pregnancy category C. This means that its effects on an unborn baby are not known. Do not take this medication without first talking to your doctor if you are pregnant. Breast-feeding- This drug combination passes into breast milk and may harm a nursing infant. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

Children-For butalbital: Although barbiturates such as butalbital often cause drowsiness, some children become excited after taking them. For acetaminophen: Acetaminophen has been tested in children and, in effective doses, has not been shown to cause different side effects or problems than it does in adults.

For caffeine: There is no specific information comparing use of caffeine in children up to 12 years of age with use in other age groups.

However, caffeine is not expected to cause different side effects or problems in children than it does in adults. Older adults-For butalbital: Certain side effects, such as confusion, excitement, or mental depression, may be especially likely to occur in elderly patients, who are usually more sensitive than younger adults to the effects of the butalbital in this combination medicine.

For acetaminophen: Acetaminophen has been tested and has not been shown to cause different side effects or problems in older people than it does in younger adults. For caffeine: Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people.

There is no specific information comparing use of caffeine in the elderly with use in other age groups. Other medicines-Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur.

In these cases, your doctor may want to change the dose, or other precautions may be necessary. It is especially important to tell your doctor if you are taking: Anticoagulants (blood thinners)Carbamazepine (Tegretol)Contraceptives containing estrogen Corticosteroids (cortisone-like medicines)Corticotropin (ACTH)Tricyclic Antidepressants Central nervous system (CNS) depressants (medicines that often cause drowsiness)Divalproex (Depakote) or Valproic acid (Depakene)Drugs other than those listed here may also interact with Acetaminophen/butalbital/caffeine.

Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines. Other medical problems-The presence of other medical problems may affect the use of frovatriptan. Make sure you tell your doctor if you have any other medical problems, especially:alcohol abuse (or history of)drug abuse or dependence (or history of)Asthma, emphysema, or other chronic lung diseasehepatitis or other liver diseasetyperactivity (in children)kidney diseasediabetes mellitusmental depressionoveractive thyroidporphyria (or history of)heart disease (severe)Proper Use of This Medicine Take Acetaminophen/butalbital/caffeine exactly as directed by your doctor.

If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water. Take Acetaminophen/butalbital/caffeine with food or milk if it upsets your stomach. Never take more of this medication than is prescribed for you. Too much Acetaminophen/butalbital/caffeine could be very harmful. Never take more than six tablets or capsules per day. Do not share this medication with anyone else. Avoid alcohol. Alcohol taken during therapy with acetaminophen and butalbital can be very damaging to your liver and can increase drowsiness and dizziness.

This medicine will relieve a head pain best if you take it as soon as the pain begins. If you get warning signs of a migraine, take this medicine as soon as you are sure that the migraine is coming.

This may even stop the head pain from occurring. Lying down in a quiet, dark room for a while after taking the medicine also helps to relieve head pain.

People who who have frequent head pain episodes may need to take a different medicine to help prevent headaches or Migraines. It is important that you follow your doctor's directions about taking the other medicine, even if your headaches or Migraines continue to occur. Preventive medicines may take several weeks to start working. Even after they do start working, your headaches or Migraines may not go away completely. However, they should occur less often, and should be less severe and easier to relieve than before.

Dosing-The dose of Fioricet will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses. If your dose is different, do not change it unless your doctor tells you to do so.

Adults—One or 2 capsules or tablets every four hours as needed. If your medicine contains 325 or 500 milligrams (mg) of acetaminophen in each capsule or tablet, you should not take more than six capsules or tablets a day. If your medicine contains 650 mg of acetaminophen in each capsule or tablet, you should not take more than four capsules or tablets a day.

Children—Dose must be determined by your doctor. Storage-To store this medicine: Keep out of the reach of children since overdose is especially dangerous in children. Store away from heat and direct light. Do not store in the bathroom, near the kitchen sink, or in other damp places.

Heat or moisture may cause the medicine to break down. Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children. Precautions While Using This Medicine Check with your doctor if the medicine stops working as well as it did when you first started using it.

This may mean that you are in danger of becoming dependent on the medicine. Do not try to get better pain relief by increasing the dose. Check with your doctor if you are having headaches or Migraines more often than you did before you started using this medicine.

This is especially important if a new episode occurs within 1 day after you took your last dose of medicine, episodes begin to occur every day, or an episode continues for several days in a row. This may mean that you are dependent on the headache medicine. Continuing to take this medicine will cause even more headaches later on.

Your doctor can give you advice on relief. Check the acetaminophen content of other over-the-counter and prescription products while taking this medication.

You should not exceed 4 grams (4000 mg) of acetaminophen per day. The butalbital in this medicine will add to the effects of alcohol and other CNS depressants (medicines that slow down the nervous system, possibly causing drowsiness). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; other prescription pain medicine or narcotics; other barbiturates; medicine for seizures; muscle relaxants; or anesthetics, including some dental anesthetics.

Also, stomach problems may be more likely to occur if you drink alcoholic beverages while you are taking Acetaminophen. Therefore, do not drink alcoholic beverages, and check with your doctor before taking any of the medicines listed above, while you are using this medicine.

This medicine may cause some people to become drowsy, dizzy, or lightheaded. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert and clearheaded.

Before having any kind of surgery (including dental surgery) or emergency treatment, tell the medical doctor or dentist in charge that you are taking this medicine. Serious side effects may occur if your medical doctor or dentist gives you certain other medicines without knowing that you have taken butalbital.

Before you have any medical tests, tell the person in charge that you are taking this medicine. Caffeine (present in some butalbital and Acetaminophen combinations) interferes with the results of certain tests that use dipyridamole (e.g., Persantine) to help show how well blood is flowing to your heart. Caffeine should not be taken for 8 to 12 hours before the test. The results of some other tests may also be affected by butalbital and Acetaminophen combinations.

If you have been taking large amounts of this medicine, or if you have been taking it regularly for several weeks or more, do not suddenly stop using it without first checking with your doctor.

Your doctor may want you to reduce gradually the amount you are taking before stopping completely, to lessen the chance of withdrawal side effects.

If you think you or anyone else may have taken an overdose of this medicine, get emergency help at once. Side Effects of This Medicine Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur, especially if several of them occur together: Rare: Bleeding or crusting sores on lips; chest pain; fever with or without chills; hive-like swellings (large) on eyelids, face, lips, and/or tongue; muscle cramps or pain; red, thickened, or scaly skin; shortness of breath, troubled breathing, tightness in chest, or wheezing; skin rash, itching, or hives; sores, ulcers, or white spots in mouth (painful); sore throat Also, check with your doctor as soon as possible if any of the following side effects occur: Less comon: confusion (mild); mental depression; unusual excitement (mild)Rare: bloody or black, tarry stools; bloody urine; pinpoint red spots on skin; swollen or painful glands; unusual bleeding or bruising ; unusual tiredness or weakness (mild)Other side effects may occur that usually do not need medical attention.

These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome: More common: Bloated or ""gassy'"" feeling; dizziness or lightheadedness (mild); drowsiness (mild); nausea, vomiting, or stomach pain Some commonly used brand names are: In the U. S.-Amaphen Anolor-300Anoquan Arcet Butace Dolmar Endolor Esgic Esgic-Plus Ezol Femcet Fioricet Isocet Medigesic Pacaps Pharmagesic Repan Tencet Triad Two-Dyne In Canada- not commercially available "

Butalbital is a short- to intermediate-acting barbiturate. It is commonly used in combination with other drugs such as acetaminophen and caffeine to treat mild to moderate pain, migraines and tension headaches.

Butalbital

This information is disseminated under the sponsorship of the U. S. Department of Transportation in the interest of information exchange. The United States Government assumes no Liability for the contents or use thereof. Butalbital Description

Specimen/blood ratio: muscle (0.66 +/- 0.09), liver (2.22 +/- 0.04), liver fluid (0.89 +/- 0.23), kidney (0.98 +/- 0.09), lung (0.87 +/- 0.06), spleen (0.75 +/- 0.03), brain (0.96 +/- 0.07), bile (0.94 +/- 0.22), heart (0.91 +/- 0.17), and urine (0.73 +/- 0.16).

Therapeutic Low 1.0000Therapeutic High 10.0000Units ug/m LSpecimen BHalf Life Low 30.00Half Life High 40.00VOD Low 0.00VOD High 1.00Toxic Level 7.000Lethal Level 13.000Plasma to Whole Blood ratio 0.00Warnings Warnings - may impair mental and/or physical ability required for the performance of potentially hazardous tasks (e.g., driving, operating heavy machinery).

2016It's confusing because both Fioricet and Fiorinal contain the same amount of butalbital (50 mg), but it all boils down to the ratio of non-narcotic to butalbital decided by the FDA to meet controlled substance exemption in 1980. Fiorinal® is required to have >188 mg of aspirin for every 15 mg of butalbital (188:15), but has 97.5 mg to 15 mg.

Why is Fiorinal (butalbital-aspirin-caffeine) a controlled substance (CIII), while Fioricet (butalbital-acetaminophen-caffeine) is not controlled when they both contain a barbiturate?

Anonymous Answered Mar 18,

For the old formulation of Fioricet, the ratio is 70 mg of acetaminophen for every 15 mg of butalbital (70:15), and has 97.5 mg per 15 mg. The FDA established these cutoffs based on what they believed were adequate amounts of aspirin or acetaminophen to reduce the abuse potential of butalbital.

It should be noted that a few states have Fioricet classified as a controlled substance (Georgia, Maryland, New Mexico, Utah, Illinois, and Rhode Island) even though Federal law doesn't. In pharmacy when presented with conflicting state and federal laws, always go with the stricter of the two. Also, the FDA national code directory lists some new formulations of Fioricet as CIII (see National Drug Code Directory ); the new formulation has 300 mg of acetaminophen instead of 325 mg, which would still fall within the original ratio established by FDA.

(see Fiorinal is a Schedule III controlled drug but Fioricet is not! )4.7k Views · View Upvoters Your response is private. Is this answer still relevant and up to date?

What are the possible side effects of aspirin, butalbital, and caffeine (Butalbital Compound, Fiorinal)? Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

aspirin, butalbital, and caffeine (Butalbital Compound, Fiorinal)

Brand Names: Butalbital Compound, Fiorinal Generic Name: aspirin, butalbital, and caffeine (Pronunciation: AS pir in, byoo TAL bi tal, KAF een)What is aspirin, butalbital, and caffeine (Butalbital Compound, Fiorinal)?

What are the possible side effects of aspirin, butalbital, and caffeine (Butalbital Compound, Fiorinal)? What is the most important information I should know about aspirin, butalbital, and caffeine (Butalbital Compound, Fiorinal)? What should I discuss with my healthcare provider before taking aspirin, butalbital, and caffeine (Butalbital Compound, Fiorinal)? How should I take aspirin, butalbital, and caffeine (Butalbital Compound, Fiorinal)? What happens if I miss a dose (Butalbital Compound, Fiorinal)?

What happens if I overdose (Butalbital Compound, Fiorinal)? What should I avoid while taking aspirin, butalbital, and caffeine (Butalbital Compound, Fiorinal)? What other drugs will affect aspirin, butalbital, and caffeine (Butalbital Compound, Fiorinal)? Where can I get more information? What is aspirin, butalbital, and caffeine (Butalbital Compound, Fiorinal)? Aspirin is a pain reliever, as well as an anti-inflammatory and a fever reducer.

Butalbital is a barbiturate. It relaxes muscle contractions involved in a tension headache. Caffeine is a central nervous system stimulant. It relaxes muscle contractions in blood vessels to improve blood flow. The combination of aspirin, butalbital, and caffeine is used to treat tension headaches.

This medicine is not for treating headaches that come and go. Aspirin, butalbital, and caffeine may also be used for purposes other than those listed in this medication guide. ASA-Butalbital-Caffeine Tab-WESround, white, imprinted with West-ward 785Prev12 3 4 Next

Stop using this medication and call your doctor at once if you have a serious side effect such as:shallow breathing, slow heart rate;fast or pounding heart rate, muscle twitching;confusion, unusual thoughts or behavior;bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;problems with urination; oreasy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin.

Less serious side effects include:drowsiness, dizziness;mild nausea, gas, upset stomach, stomach pain; orsleep problems ( insomnia ). This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

You may report side effects to FDA at 1-800-FDA-1088. What is the most important information I should know about aspirin, butalbital, and caffeine (Butalbital Compound, Fiorinal)?

Do not use this medication if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

15Fiorinal with Codeine ( butalbital, aspirin, caffeine, and codeine phosphate) is a combination of a pain reliever/anti-inflammatory/fever reducer, a barbiturate, a vasoconstrictor, and a narcotic pain reliever ( opiate -type) used to relieve complex tension headaches. Fiorinal with Codeine is available in generic form.

Fiorinal with Codeine

Fiorinal with Codeine Side Effects Center Medical Editor: John P. Cunha, DO, FACOEPLast reviewed on Rx List 9/8/20

Common side effects of Fiorinal with Codeine include nausea, vomiting, stomach upset, heartburn, gas, constipation, diarrhea, shaking ( tremor ), lightheadedness, dizziness, anxiety, agitation, drowsiness, mood changes, sleep problems (insomnia), sweating, urinating more than usual, ringing in your ears, blurred vision, or dry mouth . Dose of Fiorinal with Codeine is 1 or 2 capsules every 4 hours. Total daily dosage should not exceed 6 capsules.

Fiorinal with Codeine may interact with monoamine oxidase inhibitors (MAOIs), antidepressants, alcohol, antihistamines, sedatives, pain relievers, anxiety medicines, muscle relaxants, anticoagulants, probenecid or sulfinpyrazone, non-steroidal anti-inflammatory drugs ( NSAIDs ), aspirin and other salicylates (forms of aspirin), steroids, or insulin and oral anti-diabetic drugs.

Tell your doctor all medications you are taking. Fiorinal with Codeine is not recommended for use during pregnancy. This drug passes into breast milk and could have undesirable effects on a nursing infant. Breast-feeding is not recommended while using this drug. Butalbital and codeine are both habit-forming and potentially abusable. Withdrawal symptoms may occur when you stop taking this medication.

Our Fiorinal with Codeine (butalbital, aspirin, caffeine, and codeine phosphate) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. A Visual Guide to Migraine Headaches Slideshow Headache and Migraine Triggers Slideshow Take the Headaches Quiz Fiorinal with Codeine Consumer Information Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have a serious side effect such as:shallow breathing, slow heart rate;fast or pounding heart rate, muscle twitching;confusion, unusual thoughts or behavior;bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;problems with urination; ornausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects include:feeling dizzy, shaky, anxious, or agitated;heartburn, mild nausea, vomiting, upset stomach, constipation, diarrhea;mood changes, sleep problems (insomnia);sweating, urinating more than usual; orringing in your ears, blurred vision, or dry mouth. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Fiorinal with Codeine (Butalbital Compound With Codeine)Learn More »A Visual Guide to Migraine Headaches Slideshow Headache and Migraine Triggers Slideshow Take the Headaches Quiz Fiorinal with Codeine Professional Information SIDE EFFECTSCommonly Observed The most commonly reported adverse events associated with the use of Fiorinal with Codeine and not reported at an equivalent incidence by placebo-treated patients were nausea and/or abdominal pain, drowsiness, and dizziness.

Associated with Treatment Discontinuation Of the 382 patients treated with Fiorinal with Codeine in controlled clinical trials, three (0.8%) discontinued treatment with Fiorinal with Codeine because of adverse events.

One patient each discontinued treatment for the following reasons: gastrointestinal upset; lightheadedness and heavy eyelids; and drowsiness and generalized tingling. Incidence in Controlled Clinical Trials The following table summarizes the incidence rates of the adverse events reported by at least 1% of the Fiorinal with Codeine treated patients in controlled clinical trials comparing Fiorinal with Codeine to placebo, and provides a comparison to the incidence rates reported by the placebo-treated patients.

The prescriber should be aware that these figures cannot be used to predict the incidence of side effects in the course of usual medical practice where patient characteristics and other factors differ from those that prevailed in the clinical trials.

Similarly, the cited frequencies cannot be compared with figures obtained from other clinical investigations involving different treatments, uses, and investigators. Adverse Events Reported by at Least 1% of Fiorinal with Codeine Treated Patients During Placebo Controlled Clinical Trials Incidence Rate of Adverse Events Body System/ Adverse Event Fiorinal with Codeine (N = 382) Placebo (N = 377)Central Nervous Drowsiness 2.4% 0.5%Dizziness/Lightheadedness 2.6% 0.5%Intoxicated Feeling 1.0% 0%Gastrointestinal Nausea/Abdominal Pain 3.7% 0.8%Other Adverse Events Reported During Controlled Clinical Trials The listing that follows represents the proportion of the 382 patients exposed to Fiorinal with Codeine while participating in the controlled clinical trials who reported, on at least one occasion, an adverse event of the type cited.

All reported adverse events, except those already presented in the previous table, are included. It is important to emphasize that, although the adverse events reported did occur while the patient was receiving Fiorinal with Codeine, the adverse events were not necessarily caused by Fiorinal with Codeine.

Adverse events are classified by body system and frequency. “Frequent” is defined as an adverse event which occurred in at least 1/100 (1%) of the patients; all adverse events listed in the previous table are frequent.

“Infrequent” is defined as an adverse event that occurred in less than 1/100 patients but at least 1/1000 patients. All adverse events tabulated below are classified as infrequent. Central Nervous: headache, shaky feeling, tingling, agitation, fainting, fatigue, heavy eyelids, high energy, hot spells, numbness, and sluggishness.

Autonomic Nervous: dry mouth and hyperhidrosis. Gastrointestinal: vomiting, difficulty swallowing, and heartburn. Cardiovascular: tachycardia. Musculoskeletal: leg pain and muscle fatigue. Genitourinary: diuresis. Miscellaneous: pruritus, fever, earache , nasal congestion, and tinnitus. Voluntary reports of adverse drug events, temporally associated with Fiorinal with Codeine, that have been received since market introduction and that were not reported in clinical trials by the patients treated with Fiorinal with Codeine, are listed below.

Many or most of these events may have no causal relationship with the drug and are listed according to body system. Central Nervous: abuse, addiction, anxiety, depression, disorientation, hallucination, hyperactivity, insomnia, libido decrease, nervousness, neuropathy, psychosis, sedation, sexual activity increase, slurred speech, twitching, unconsciousness, vertigo. Autonomic Nervous: epistaxis, flushing, miosis , salivation. Gastrointestinal: anorexia, appetite increased, constipation, diarrhea, esophagitis, gastroenteritis, gastrointestinal spasm, hiccup, mouth burning, pyloric ulcer. Cardiovascular: chest pain, hypotensive reaction, palpitations, syncope. Skin: erythema, erythema multiforme, exfoliative dermatitis, hives, rash, toxic epidermal necrolysis. Urinary: kidney impairment, urinary difficulty. Miscellaneous: allergic reaction, anaphylactic shock, cholangiocarcinoma, drug interaction with erythromycin (stomach upset), edema.

The following adverse drug events may be borne in mind as potential effects of the components of Fiorinal with Codeine. Potential effects of high dosage are listed in the OVERDOSAGE section of this insert. Aspirin: occult blood loss, hemolytic anemia, iron deficiency anemia, gastric distress, heartburn, nausea, peptic ulcer, prolonged bleeding time, acute airway obstruction, renal toxicity when taken in high doses for prolonged periods, impaired urate excretion, hepatitis.

Caffeine: cardiac stimulation, irritability, tremor, dependence, nephrotoxicity, hyperglycemia. Codeine: nausea, vomiting, drowsiness, lightheadedness, constipation, pruritus. Drug Abuse And Dependence Controlled Substance Fiorinal with Codeine is controlled by the Drug Enforcement Administration and is classified under Schedule III. Abuse and Dependence Codeine Codeine can produce drug dependence of the morphine type and, therefore, has the potential for being abused.

Psychological dependence, physical dependence, and tolerance may develop upon repeated administration and it should be prescribed and administered with the same degree of caution appropriate to the use of other oral narcotic medications. Butalbital Barbiturates may be habit-forming: Tolerance, psychological dependence, and physical dependence may occur especially following prolonged use of high doses of barbiturates.

The average daily dose for the barbiturate addict is usually about 1,500 mg. As tolerance to barbiturates develops, the amount needed to maintain the same level of intoxication increases; tolerance to a fatal dosage, however, does not increase more than twofold.

As this occurs, the margin between an intoxication dosage and fatal dosage becomes smaller. The lethal dose of a barbiturate is far less if alcohol is also ingested. Major withdrawal symptoms (convulsions and delirium) may occur within 16 hours and last up to 5 days after abrupt cessation of these drugs. Intensity of withdrawal symptoms gradually declines over a period of approximately 15 days. Treatment of barbiturate dependence consists of cautious and gradual withdrawal of the drug. Barbiturate-dependent patients can be withdrawn by using a number of different withdrawal regimens.

One method involves initiating treatment at the patient's regular dosage level and gradually decreasing the daily dosage as tolerated by the patient. Read the entire FDA prescribing information for Fiorinal with Codeine (Butalbital Compound With Codeine)Read More »A Visual Guide to Migraine Headaches Slideshow Headache and Migraine Triggers Slideshow Take the Headaches Quiz Related Resources for Fiorinal with Codeine Related Health Tension Headache (Symptoms, Relief, Causes, Treatment)© Fiorinal with Codeine Patient Information is supplied by Cerner Multum, Inc. and Fiorinal with Codeine Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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Charts & graphs: Reviews Summary for BUTALBITAL, ACETAMINOPHEN AND CAFFEINE | Top 10 Adverse Effects (reported to FDA)

Drug Ratings for BUTALBITAL, ACETAMINOPHEN AND CAFFEINE

"Drug Ratings for BUTALBITAL, ACETAMINOPHEN AND CAFFEINERate BUTALBITAL, ACETAMINOPHEN AND CAFFEINEAverage Rating: 4.3 (20 Ratings)Compare BUTALBITAL, ACETAMINOPHEN AND CAFFEINE with similar: ANALGESICS-NON-NARCOTIC DEA Schedule IIIResults are sorted by Date added .

Key to Ratings: 1=LOW (I would not recommend taking this medicine.) 5=HIGH (this medicine cured me or helped me a great deal. )Page: 1Filter Results

RATING REASON SIDE EFFECTS FOR BUTALBITAL, ACE COMMENTS SEX AGE DURATION/ DOSAGE DATE ADDEDF M3 Migraine headaches It made me nauseous. It helped the headaches but really made me nauseous. M 10 1 days 4/4/20185 Migraines Occasional drowsiness, possible rebound headaches. If I take 2 at the start of a headache it goes away within 15 minutes. If taken while headache is full blown, I'll take 3 and it still works wonders.

I do think I get rebound headaches but I have a headache everyday anyways so it's hard to tell. F 23 1 years 2/2/2016 Email5 migranes very mild relaxed feeling, nothing else.

This has been a great drug for my occasional migranes triggered by food/ drink, or stress. I take 3 pills one time to wipe out a headache that would otherwise ruin my entire day.

For bad headaches, can add aspirin or advil to boost effect. M 59 10 years 1X D 5/22/20154 Chronic tension headaches This is a very ""clean"" drug fro me. I have experienced minimal side effects. Sometimes it makes me drowsy, if my headache is pretty bad. It is the only drug that will decrease the intensity of my headaches. Although this drug has been associated with rebound headaches, I have not had this problem.

Neither have I had a tolerance problem. I pretty much take the same dosage as I have been taking for the past nine years. However, I do not have what I call an ""addictive"" personality. I have never been drunk before; the only time that I tried I got sick and vomited.

I never experimented with illegal recreational drugs, thus I have never been ""high"". Maybe this is why I have not had problems with drug tolerance or rebound headaches. M 58 9 years 2 x 50 mg 3X D 1/9/2014 Email1 Migraine No side effects... it just didn't have any effect on my type of migraine.

F 47 3 days 7/1/20125 Stress and pre-migraine headaches Initially just mildly spacey but now I am very used to them and can take them and drive and work.

I often feel they make more alert and clear headed and able to think once I got used to them. This is a very effective drug for alot of different kinds of headaches. Stress headaches and great for heading off a migraine but, I find only Imitrex works for completely nailing a migraine. F 56 15 years 7/18/2009 Email5 migraines maybe a jolt of energy...if i take two def works wonders!

saves me trips to the ER. i take on the onset of any tension headache or migraine and it's gone! nice... F 37 7 years 6/14/2009 Email5 migraines Some hyperness, insomnia. Sandoz brand had less side effects and 30 to 50% more effective than generic; Watson brand name and generic is lousy, more stomach pain and constipation.

Also take the fioricet and fiorinal with codeine which always works. Been taking fiorinal 3 for 23 yearss, 30 to 50 per month the first 13 years.

I have migraines that last 10 days/24 hours, used to have to stay in bed in pain with aspirin poisoning on top of the migraine nausea. Ulcers now require Fioricet instead of Fiorinal (aspirin) - unfortunately tylenol doesn't work for me for pain or fever, so I need the codeine in Fioricet #3.

Some rebound headache, but if taking lots of vicodin or percocet for my ruptured discs I can go 10 days without needing a fioricet without dependency or withdrawal syptoms. Vicodin, Fentynl, dilaudin and oxycontin do NOT work for migraines, only Fiorinal/Fioricet #3. Degerateive discs in my neck cause constant headaches, 24/7 for last 10 years, the worst pain upon waking up.

Fioricet #3 usually works for this also, neck pain headaches in last 10 years will respond to large doses of the other opiates, but migraines do not.

Migraines from weather fronts, smells, some foods, flourescent lighting flicker, computer moni F 56 23 years 2/19/20095 Headaches The only medication that kills my headaches every time I use it, about once a week. Even strong opiates do not eliminate my headaches, but butalbital is very effective. Excellent medication with no side effects for me.

M 68 900 days 1/16/20095 headaches no negative side effects. Although I've had bad headaches (tension, migraines, etc...) most of my life, I started taking this drug following a severe closed head injury.

I have always believed that self medicating should be avoided if possible. I don't want to feel like I need to be ""medicated"" to deal with life.

That being said, I also think if you find something that works as well as this medication does for otherwise debilitating headaches, you should take advantage of it and stop suffering. This is by far the most effective headache medicine I've ever taken (I've tried too many others to list).

I take one or two tablets when I feel the headache increasing and can tell it's about take control and there would be nothing I could do to stop it.

Before this drug, my headaches would take me out of commission for days at a time. Now I can nip them in the bud before they get the best of me. Washing them down with a caffeinated beverage helps even more (and I'm not normally a caffeine drinker). F 33 9 years 6/6/20085 The pill sleepy, relaxed I have been suffering from severe headeaches for about a year due to Yazmin. Like clockwork I experience a headache 3 days after I end a pack and the day I start a new one. My doctor says its due to the drop/change in hormones. (This month I am switching to Yaz which has a lower dosage.) I am unable to take ibuprophin anymore due to an ulcer.

He advised me I could get addicted and I need to only take when the headache won't go away after trying other things. (Drinking water, hot shower, shoulder massage, etc) I woke up with a headache and came home today in absolute agony and after 2 showers decided I couldn't handle it anymore.

I took 1 pill and within 10 minutes I was experiencing a huge relief. Within 30 minutes the headache was gone. This stuff is great! F 36 2 days 2/28/20085 Migraines Dry mouth and euphoric fealing Ive tried every migrane med you can pronounce...this is by far the most effective at treating my pain.

Careful...this drug makes you feel good and you want to take more. Can be habit forming. I take as needed and works wonders for my pain and makes me feel good at the same time M 35 2 years 1/1/20084 years of severe migraine constipation, dizziness, drowsiness Acetaminophen doesn't do anything for me, in any form, nor did Imitrex (despite hideous side effects). This works well enough that if I use half a pill within a few hours of a migraine starting it can knock it back to a mere headache. However, nothing works after the aura starts. Like all painkillers used for migraine (including OTC remedies), use sparingly to avoid the vicious cycle of rebound headaches. The only way to cure those is to use NOTHING AT ALL for a full month, then start with very small and sparing dosages of OTC remedies.

I've used this for a few years, limiting monthly use to 2-3 at most no matter how bad or frequent my migraines because I don't want to have to do the above detox ever again!! F 41 3 years 10/1/20075 migraine headaches Rarely, if I haven't eaten, heartburn. This is the only painkiller that has been effective for my migraines, and I haven't found it habit-forming, but then I *only* take it when I have a migraine.

Works better, of course, the sooner you take it. Migraine preventatives, such as Wygrain (sp?) worked a for a while for me (say, two or three months), but usually resulted in a more severe migraine when it finally arrived, so I have found this to be a better fit for me.

The time refers to how long I have been taking it, but NOT continuously, only as needed. F 56 43 years 7/19/20065 severe tension headaches No side effects Love this drug!

Have tension headaches that proceed to migraines if not stopped. This med stops my headaches and has helped me stay at work and functional. I do not notice any sleepiness or ""buzz"" from it at all. I am completely functional, which is so much better than the other meds which made me incapable of working.

F 44 1 years 1/17/20062 migraines sleepyness, vomiting, dizzyness I started taking for migraines (which I have suffered from for 12 years) The first 4 worked well but the 5th didn't work and I had to go through a lot of paper work b/c I failed a drug test for work b/c of butalbital.

On the 6th pill I took for instant migrain, it did not work it made me even worse, I vomitted for hours before my boyfriend finally took me to the E. R. where the doctor treated me and told me never to take it again! F 20 4 months 5/26/20054 F 1/11/20054 migraines sleepiness does not work when migraine exceeds early stages.

M 42 1 years 11/29/20045 migraines I havn't experienced any side affects that were noticable after taking 43 pills over the course of about a year. However now that I know they are addictive I will be taking them fewer and farther between. Great migraine stopper. Cured the worst migraine I have ever had in 15 minutes flat. M 15 1 years 1/2/20035 migraines was not told and did not realize it was addictive. Because of this, I got rebound headaches EVERY DAY. I would be totally out of commission day after day. Use only if headache gets ahead of you before you can take something else that works at the onset of headache. If possible, use something else. F 60 years 3/16/2001BACK TO TOPPage: 1 "

Butalbital is a barbiturate drug classified as a depressant, more commonly known under the name Fioricet. It is often prepared in combination with acetaminophen, butalbital, and caffeine and is prescribed for the treatment of tension headaches, facial pain, migraines, insomnia, anxiety issues and general pain. Occasionally, the drug is also combined with the narcotic Codeine to enhance pain-relieving properties.

Butalbital

By binding with receptors in the body, Butalbital acts as a sedative by reducing muscle tension and alleviating anxiety, causing the patient to relax. Falling under the barbiturate category, Butalbital is a sleep-inducing drug that acts as a strong central nervous system depressant.

The medication has the ability to depress the user’s senses, decrease motor activity, alter brain function and produce sedation, hypnosis and dose-dependent respiratory depression. It can also cause nightmares and hallucinations. Butalbital has the potential to be abused or to cause addiction because of the strong barbiturate medication contained in it. When the drug is taken for more than one month’s time, brain chemistry is altered and the brain develops a need for the drug in order to function.

Severe symptoms can occur if the drug is then suddenly withheld from the user. Butalbital: How it Works in The Body Butalbital, or Fioricet, contains numerous substances that all serve their own purpose when taken.

Let’s take a closer look at all of the ingredients in this prescription medication and what their effects are on the body: Acetaminophen Acetaminophen is considered a mild painkiller, and is the main ingredient in Tylenol. It can help block pain from headaches or relieve general body pain. Butalbital This central nervous system depressant causes drowsiness, sedation and can impair the user’s senses.

It is one of two potentially addictive substances in Fioricet. Caffeine Caffeine is considered a mild stimulant that helps increase users awareness and to be more alert. It can also ease headache pain. Codeine This is an opioid pain medication used to treat mild to moderately severe pain. This would be considered the second potentially addictive substance in Fioricet, though not all types of Fioricet have Codeine added.

Butalbital Abuse and Street Usage Butalbital can become habit forming with prolonged use or by abusing the dosage.

Many abusers are people suffering from tension headaches, sleep disorders and migraines. The average daily dosage for someone addicted to Butalbital is about 1,500 mg per day, although this amount varies greatly among addicts. As the body’s tolerance for the drug increases, the need to increase the dosage of the drug is necessary to maintain the desired level of intoxication and feeling of euphoria.

The person abusing the drug can ingest too much Butalbital because of this tolerance, which can lead to the possibility of a fatal overdose. When Butalbital is paired with alcohol, it becomes even more dangerous and places the user at severe risk for adverse or life threatening reactions. For some drug addicts, Butalbital is more than a mood relaxer or pain medication. The pills are often considered secondary drugs, as they act like a downer or stabilizer for those also taking stimulants such as cocaine or methamphetamines.

Street names for Butalbital or Fioricet include yellow jackets, downers, goof balls, red devils, or double trouble. Butalbital is considered to have a small therapeutic-to-toxic window, meaning there is a fine line between a dosage that would lead to drowsiness or euphoria in a user or one that can lead to coma or death. Usage and Side Effects of Butalbital Butalbital is most often taken orally and comes in solid tablet form, capsule or solution, and can also be crushed up into a powder.

Some forms of the drug have a very long half-life that enable it to accumulate in the body, with repeat doses causing more side effects.

Common side effects of Butalbital may include: Dizziness Drowsinesslight-headedness,Feelings of intoxication Nausea Sedation Euphoric feelings Severe impairment of judgment Side effects that are more serious can include: Seizures Coma Respiratory depression Fast or irregular heartbeat Shortness of breath Shock Addiction to Butalbital: The Signs The need to satisfy the increasing physical and psychological drug dependence of Butalbital puts the user at great risk.

Addicts will sometimes engage in dangerous behavior in order to obtain drugs. His or her appearance can also change dramatically over time and he or she may gain or lose weight. They may also lose interest in activities they once enjoyed and will often seek seclusion and withdraw from loved ones. A Butalbital addict may start to lose performance skills and can exhibit memory loss, depression, confusion, anxiety, hostility, aggression, and increased heart rate.

They run the risk of losing important relationships like family and friends and can also experience the loss of their health and employment. Butalbital Withdrawal and Detoxification Because of the intense physical and psychological dependence effects Butalbital can have on the body, withdrawing from the drug suddenly can cause severe symptoms.

The user may experience sweating, muscle pain, agitation, insomnia, hallucinations and even seizures. These withdrawal symptoms can last up to sixteen days after the final barbiturate dose. Since Butalbital withdrawal symptoms can be moderate to severe, it is not suggested that a user stop taking the drug or attempt to detox on his or her own without medical support or the help of a rehabilitation treatment center.← A to Z Addictive Substances

Fioricet is a combination drug that includes butalbital, acetaminophen and caffeine. Butalbital is a barbiturate and acetaminophen is the active ingredient in Tylenol. It is approved for the treatment of tension headaches and muscle contraction headaches.

Qualitest Generic Vicodin and Fioricet Recall: Label Mix Up

Qualitest Generic Vicodin and Fioricet Recall: Label Mix Up June 28, 2011 Written by: Staff Writers 2 Comments Federal drug regulators are warning that some bottles of Qualitest generic Vicodin and Fioricet may have had their labels swapped due to a manufacturing problem, meaning that some patients could be taking the wrong drugs.

A Qualitest generic drug recall was announced on June 27 after at least one bottle of generic Fioricet was found with a generic Vicodin label. The FDA and Qualitest warn that unintentional Fioricet consumption by people with an allergy to butalbital, one of its active ingredients, could result in a hypersensitivity reaction.

They also warn that those who were already on Vicodin could experience increased pain and withdrawal symptoms. There were no reports of anyone having suffered adverse events due to the labeling mix-up.

Vicodin (hydrocodone and acetaminophen) is a powerful opioid painkiller approved to relieve moderate to severe pain. It and generics that use the same active ingredients are prescribed more than 100 million times a year in the United States.

The recall affects four lots of 500-count bottles of Butalbital, Acetaminophen, and Caffeine Tablets, USP, 50mg/325mg/40mg, by Qualitest. The lot numbers are C0390909A, C0400909A, C0410909A, and C0590909B, and the bottles have NDC 0603-2544-28. It also affects four lots of 1,000-count bottles of Hydrocodone Bitartrate and Acetaminophen Tablets, USP 7.5mg / 500mg, by Qualitest, with lot numbers C0390909A, C0400909A, C0410909A, and C0590909B, and NDC 0603-3882-32.

The lots were distributed between November 13, 2009 and April 9, 2010. The FDA recommends that any consumers who received a prescription from either affected medications check to visually ensure they have the right pills. The generic Fioricet pills are white, have 2544 stamped into them on one side and a “V” on the other and are 11 mm in diameter.

The generic Vicodin pills are 16.5 mm in length and are white with green specks, capsule shaped with 3594 stamped on one side, as well as a “V” on the other side. This is the second time this year Qualitest has had to recall generic Vicodin and a barbiturate due to a label mix-up. On February 5, 2011, three lots of generic Vicodin and Phenobarbital were recalled after a bottle of Vicodin was found with a Phenobarbital label.

In January, the FDA announced that it was placing limits on the amount of acetaminophen in Vicodin, Percocet and similar painkillers.

The agency is also requiring stronger label warnings regarding the risks of liver injury. Tags: Acetaminophen, Fioricet, Phenobarbital, Qualitest, Vicodin2 comments Peter October 15, 2011 at 8:11 pm Reply Had stroke in 2001. I have written medication documentation list that was given to me after I was release from this hospital.

St Francis Medical Center, Tacoma Washington. Also on that medicatio list is Simvastin which I had taken for more than 5 years.. Cheryl January 25, 2013 at 4:17 pm Reply I have been taking Fioricet for years, since 1977 to be exact. This medication has helped in some cases but mostly has caused many financial, mental trauma, suicide attempts, seizures and many other problems in this now 35 years of use.

Other medications do not provide the relieve from my cluster tension headaches like Fioricet w/o Codeine does but the other side effects far out way the benefit and therefore I have been on a long path of recovery from detoxing from this medication.

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Fiorinal contains a combination of aspirin, butalbital, and caffeine. Aspirin is a pain reliever, as well as an anti-inflammatory and a fever reducer. Butalbital is a barbiturate. It relaxes muscle contractions involved in a tension headache. Caffeine is a central nervous system stimulant. It relaxes muscle contractions in blood vessels to improve blood flow. Fiorinal is used to treat tension headaches.

Fiorinal

Fiorinal Generic Name: aspirin, butalbital, and caffeine (AS pir in, byoo TAL bi tal, KAF een) Brand Names: Butalbital Compound, Fiorinal Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Drug Images Support Group Q & APricing & Coupons What is Fiorinal?

This medicine is not for treating headaches that come and go. Fiorinal may also be used for purposes not those listed in this medication guide. Slideshow Chronic Pain Management: A Healthcare Professional's Guide Important information You should not use Fiorinal if you have a stomach ulcer, severe liver disease, porphyria, a bleeding or blood clotting disorder, or if you are allergic to any NSAID. Aspirin may cause stomach or intestinal bleeding, which can be fatal. Stop using Fiorinal and call your doctor at once if you have: black, bloody, or tarry stools, and coughing up blood or vomit that looks like coffee grounds.

Aspirin should not be given to a child or teenager who has a fever. Butalbital may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death. Before taking this medicine Aspirin may cause stomach or intestinal bleeding, which can be fatal.

This can occur without warning while you are taking this medicine. You should not use Fiorinal if you are allergic to aspirin, butalbital, or caffeine, or if you have:stomach ulcer;severe liver disease;porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system);a bleeding or blood clotting disorder (such as hemophilia); orasthma, or a history of severe allergic reaction (sneezing, runny or stuffy nose, wheezing, shortness of breath) after taking aspirin or another NSAID (nonsteroidal anti-inflammatory drug) such as Advil, Motrin, Aleve, Celebrex, Orudis, Indocin, Lodine, Voltaren, Toradol, Mobic, Relafen, Feldene, and others.

To make sure Fiorinal is safe for you, tell your doctor if you have:liver or kidney disease;asthma or another respiratory disease;fluid retention;heart disease, congestive heart failure, high blood pressure;a history of head injury or brain tumor;a stomach or intestinal disorder;a thyroid disorder;enlarged prostate or urination problems; or Addison's disease (an adrenal gland disorder).

It is not known whether Fiorinal will harm an unborn baby. If you use butalbital while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.

Taking aspirin during late pregnancy may cause bleeding in the mother or the baby during delivery. Tell your doctor if you are pregnant or plan to become pregnant. Aspirin, butalbital, and caffeine can pass into breast milk and may harm a nursing baby. Aspirin use while breast-feeding could cause bleeding in the infant. You should not breast-feed while using Fiorinal. Do not give this medicine to a child or teenager with a fever, flu symptoms, or chicken pox. Aspirin can cause Reye's syndrome, a serious and sometimes fatal condition in children.

How should I take Fiorinal? Take Fiorinal exactly as prescribed. Follow all directions on your prescription label. Never use Fiorinal in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in relieving your headache.

Butalbital may be habit-forming. Never share Fiorinal with another person, especially someone with a history of drug abuse or addiction. Keep Fiorinal in a place where others cannot get to it. Misuse of habit-forming medicine can cause addiction, overdose, or death.

Selling or giving away this medicine is against the law. If you need surgery, tell the surgeon ahead of time that you are using Fiorinal. You may need to stop using the medicine for a short time. Do not stop using this medicine suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using Fiorinal. Store at room temperature away from moisture and heat.

Keep track of the amount of medicine used from each new bottle. Fiorinal is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription. Fiorinal dosing information Usual Adult Dose of Fiorinal for Pain:1 to 2 tablets or capsules orally every 4 hours as needed. Maximum of 6 tablets or capsules daily. See also: Dosage Information (in more detail)What happens if I miss a dose?

Since this medicine is used when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of butalbital can be fatal. Overdose symptoms may include extreme drowsiness, confusion, restless feeling, insomnia, tremors, fast heart rate, vomiting, stomach pain, rapid breathing, feeling hot, ringing in your ears, weak or shallow breathing, seizure (convulsions), or fainting.

What should I avoid while taking Fiorinal? This medication may impair your thinking or reactions. Avoid driving or operating machinery until you know how the medicine will affect you. Ask a doctor or pharmacist before using any cough, cold, allergy, or pain medication.

Aspirin and caffeine are contained in many combination medicines. Taking certain products together can cause you to get too much of a certain drug.

Check the label to see if a medicine contains aspirin or caffeine. Do not drink alcohol. Dangerous side effects, overdose, or death can occur when alcohol is combined with butalbital. Alcohol may increase your risk of stomach bleeding while you are taking aspirin. Fiorinal side effects Get emergency medical help if you have signs of an allergic reaction to Fiorinal: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:shallow breathing, slow heart rate;fast or pounding heart rate, muscle twitching;confusion, unusual thoughts or behavior;symptoms of stomach bleeding - bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;problems with urination; oreasy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin.

Serious side effects may be more likely in older adults and those who are ill or debilitated. Common Fiorinal side effects include:drowsiness, dizziness;nausea, gas, upset stomach, stomach pain; orsleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. See also: Side effects (in more detail)What other drugs will affect Fiorinal?

Taking this medicine with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before taking a sleeping pill, narcotic pain medicine, prescription cough medicine, a muscle relaxer, or medicine for anxiety, depression, or seizures.

You should not use Fiorinal if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Tell your doctor about all your current medicines and any you start or stop using, especially:mercaptopurine;methotrexate;probenecid;insulin or oral diabetes medicine;a blood thinner - warfarin, Coumadin, Jantoven; orsteroid medicine - prednisone, dexamethasone, and others.

This list is not complete. Other drugs may interact with aspirin, butalbital, and caffeine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Next → Side Effects Add to My Med List More about Fiorinal (aspirin / butalbital / caffeine)Side Effects During Pregnancy Dosage Information Drug Images Drug Interactions Support Group Pricing & Coupons En Español63 Reviews – Add your own review/rating Generic Availability Drug class: analgesic combinations Consumer resources Fiorinal Professional resources Fiorinal (FDA)Other Formulations Fiorinal with Codeine Related treatment guides Migraine Headache Pain Where can I get more information?

Your pharmacist can provide more information about Fiorinal. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Fiorinal only for the indication prescribed.

Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect.

Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise.

Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient.

Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Copyright 1996-2018 Cerner Multum, Inc. Version: 2.03. Revision Date: 2016-11-28, 8:11:05 PM.

Fioricet contains a combination of acetaminophen, butalbital, and caffeine Acetaminophen is a pain reliever and fever reducer. Butalbital is in a group of drugs called barbiturates. It relaxes muscle contractions involved in a tension headache. Caffeine is a central nervous system stimulant.

Fioricet

Fioricet Generic Name: acetaminophen, butalbital, and caffeine (a SEET a MIN oh fen, bue TAL bi tal, and KAF een) Brand Names: Capacet, Esgic, Fioricet, Margesic, Medigesic, Orbivan, Repan, Vanatol LQ, Zebutal Medically reviewed: January 25, 2018Overview Side Effects Dosage Professional Tips Interactions Pregnancy Warnings User Reviews More Drug Images Support Group Q & ACompare Alternatives Pricing & Coupons What is Fioricet?

It relaxes muscle contractions in blood vessels to improve blood flow. Fioricet is used to treat tension headaches that are caused by muscle contractions. Fioricet may also be used for purposes not listed in this medication guide. Slideshow10 Common Symptoms That Should Never Be Ignored Important information You should not use Fioricet if you have porphyria, or if you have recently used alcohol, sedatives, tranquilizers, or other narcotic medications.

Do not use Fioricet if you have taken a MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine. Do not take more Fioricet than is recommended. An overdose of acetaminophen can damage your liver or cause death.

Call your doctor at once if you have nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of your skin or eyes). In rare cases, acetaminophen may cause a severe skin reaction. Stop taking Fioricet and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.

Before taking this medicine Do not use Fioricet if you have taken an MAO inhibitor in the past 14 days.

A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine. You should not use Fioricet if you are allergic to acetaminophen, butalbital, or caffeine, if you have porphyria, or if you have recently used alcohol, sedatives, tranquilizers, or other narcotic medications.

To make sure Fioricet is safe for you, tell your doctor if you have:liver disease, cirrhosis, a history of alcoholism or drug addiction, or if you drink more than 3 alcoholic beverages per day;kidney disease;asthma, sleep apnea, or other breathing disorder;stomach ulcer or bleeding;a history of skin rash caused by any medication;a history of mental illness or suicidal thoughts; orif you use medicine to prevent blood clots.

It is not known whether Fioricet will harm an unborn baby. If you use butalbital while you are pregnant, your baby could become dependent on the drug.

This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant. This medicine can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby. How should I take Fioricet? Take Fioricet exactly as prescribed.

Follow all directions on your prescription label. Do not take more of this medication than recommended. An overdose can damage your liver or cause death. Tell your doctor if the medicine seems to stop working as well in relieving your pain.

Butalbital may be habit-forming. Never share Fioricet with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it. Selling or giving away Fioricet is against the law. Take Fioricet with food or milk if it upsets your stomach. Store Fioricet at room temperature away from moisture and heat. Keep track of the amount of medicine used from each new bottle. Butalbital is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Fioricet dosing information Usual Adult Dose of Fioricet for Headache: Acetaminophen 300 mg, butalbital 50 mg, and caffeine 40 mg: 1 or 2 capsule (s) orally every 4 hours as needed. Maximum daily dose: 6 doses. Acetaminophen 325 mg, butalbital 50 mg, and caffeine 40 mg: 1 or 2 tablet (s), capsule (s), or tablespoonful (s) orally every 4 hours.

Maximum daily dose: 6 doses Acetaminophen 500 mg, butalbital 50 mg, and caffeine 40 mg: 1 tablet or capsule orally every 4 hours. Maximum daily dose: 6 doses Acetaminophen 750 mg, butalbital 50 mg, and caffeine 40 mg: 1 tablet orally every 4 hours.

Maximum daily dose: 5 tablets Usual Pediatric Dose of Fioricet for Headache:12 years and older: Acetaminophen 300 mg, butalbital 50 mg, and caffeine 40 mg: 1 or 2 capsule (s) orally every 4 hours as needed. Maximum daily dose: 6 doses. See also: Dosage Information (in more detail)What happens if I miss a dose?

Since this medicine is used when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember.

Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Fioricet can be fatal. The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness.

Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes. Overdose symptoms may also include insomnia, restlessness, tremor, diarrhea, increased shallow breathing, uneven heartbeats, seizure (convulsions), or fainting.

What should I avoid while taking Fioricet? This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It may increase your risk of liver damage while taking acetaminophen. Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose.

Check the label to see if a medicine contains acetaminophen or APAP. While you are taking this medication, avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor's advice.

Fioricet side effects Get emergency medical help if you have signs of an allergic reaction to Fioricet: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. In rare cases, acetaminophen may cause a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen in the past and had no reaction.

Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.

If you have this type of reaction, you should never again take any medicine that contains acetaminophen. Stop using this medicine and call your doctor at once if you have:confusion, seizure (convulsions);shortness of breath;a light-headed feeling, like you might pass out; ornausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). Common Fioricet side effects may include:drowsiness, dizziness;feeling anxious or restless;drunk feeling; orsleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. See also: Side effects (in more detail)What other drugs will affect Fioricet?

Taking this medicine with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before taking Fioricet with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.

Other drugs may interact with acetaminophen, butalbital, and caffeine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using. Next → Side Effects Add to My Med List More about Fioricet (acetaminophen / butalbital / caffeine)Side Effects During Pregnancy Dosage Information Drug Images Drug Interactions Compare Alternatives Support Group Pricing & Coupons En Español125 Reviews – Add your own review/rating Drug class: analgesic combinations Consumer resources Fioricet Fioricet Oral (Advanced Reading)Other brands: Esgic, Esgic-Plus, Ezol, Geone, ... +9 more Professional resources Fioricet (FDA)Fioricet Capsules (FDA)Other Formulations Fioricet with Codeine Related treatment guides Headache Where can I get more information?

Your pharmacist can provide more information about Fioricet. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Fioricet only for the indication prescribed.

Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect.

Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise.

Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Copyright 1996-2018 Cerner Multum, Inc. Version: 6.02.

I was also prescribed Floricet by my doctor who is not a neurologist. I noticed that it helped with lesser, tension-type headaches but not full blown migraines. It’s my belief that it is because it has almost the same ingredients as OTC Exedrin (ie. caffeine and tylenol) with the exception of the Butalbital.

Fioricet

Fioricet SHARE RATE ★ ★ ★ ★ ★Home › Forums › Medications & Prescription Treatment › Fioricet Author Posts October 25, 2010 at 8:22 pm #40348admin Participant Welcome to the Fioricet Forum April 21, 2011 at 6:48 pm #41587lizzie Participant Looks like I’m the only one out there still taking Fioricet!

I tried everything available 25 years ago, including preventive meds. Since menopause, my headaches aren’t as severe and the Fioricet usually works, but sometimes I have to take two or three of them in a day. July 18, 2011 at 8:33 pm #41588sashamcinnis Participant

So in other words, I felt loopy and caffeinated at the same time. This med didn’t work for me. Hope my post was helpful. July 19, 2011 at 3:23 am #41589Kym Participant Fioricet doesn’t work for me but Fiorinal with codeine is the only thing that I can tolerate that does work for me.

I’ve tried and tried and tried and tired what feels like a million other meds from abortive to rescue but the Fiorinal #3 is the only one that I can consistently take that works, that I can tolerate and that still allows me to be somewhat functioning. August 15, 2011 at 1:32 pm #41590britany Participant I take fioricet and find it to work but my doctor says not to take more than like 2 pills in a month or i will get rebound headaches… =/ so i try not to take more than that if i can help it.

February 29, 2012 at 6:45 am #41591jillybean Participant I was prescribed fioricet and I never noticed a difference except like one user said, feeling dopey but caffeinated.

I have found Inderal to help control my migraines and when I do have a break through migraine percocet 5mg normally help. I hope this is helpful. March 1, 2012 at 4:14 pm #41592Anonymous Butalbital compounds (Fioricet, Fiorinal, Esgic, for example) have never been shown to help any headache in any scientific studies and cause more problems than they should. They are not recommended by most headache specialists. And they are still commonly prescribed so no you are not alone.

April 5, 2015 at 10:42 pm #62121st0rky Participanthmmm well they work no matter what the studies say. I have suffered from migraines since I was young girl and hormonal time of the month WOW did I suffer (of course no help from doctors).

I only ever took Tylenol and/or migraine w/excederin until my mid 30’s I suffered a ruptured brain aneurysm. now I suffer daily combination of cluster, tension and down and out migraines w/numbness and aura @ hormonal time of the month and ONLY fioricet w/codeine works. also, Dr Whyte, after reading your comments below about rebound, etc. etc. I think you should be more specific. I have read and read for years, talked to docs and nobody has the answers. for ME, I cant take NSAIDS as I take aspirin for blood thinner. narcotics are not the only drug causing rebound, so do nsaids Tylenol immitrex on and on, so I find your comments misleading.

not to mention, my awesome surgeon has advised that ONLY those who have migraine syndrome will get rebound headaches meaning they truly do suffer even if some stigmatize their pain as not real. priorto taking the fioricet w/codeine, I took soooo many Tylenol i’m surprised my liver still functioned so I decided to take the narcotic as prescribed and it has been a lifesaver.

sure I still struggle but w/out them i would never leave my couch and quite frankly it’s a choice of living or not, at least for me. rebound/addiction is scary but a migraine is even scarier sooo… you should read the article written by a doc @ Jefferson hospital about migraine sufferers being more stigmatized than those suffering from mental illness.

sad, as I waited for the helicopter to take me to top hospital for surgery, I felt vindicated when I had a brain aneurysm rupture like now everyone will believe my pain. March 2, 2012 at 3:42 am #41593Shelley Participant I was also prescribed Fioricet by my doctor, but not my neurologist. I have been taking them now for a few years,not daily, but 2-3 times a week in the last 4-5 months when my headaches are very bad. My neurologist gave me Lortab but I don’t like how that makes me feel and I don’t want to take it while i’m working during the day. I have found that nothing much works lately. I have been having headaches daily. My doctor didn’t mention rebound headaches, but after reading info on this site, I’m beginning to think that may be what I am having.

March 13, 2012 at 11:21 pm #41594shaneandnikkiredding Participant I have intercystial cystitis and Recently started having severe migraines again. My neurologist recommended my urologist take me off elmiron because he feels its part of the problem but they said its not a medication I can stop. That being said I went in to my medical doctor this morning and she prescribed Fioricet. When my neuro doctor finally called me back this afternoon and I told him what she prescribed he told me NOT to take it and if I choose to he will no longer treat me.

So now I’m back to square ! and feel like i basically have a choice live with the migraines or stop the elmiron and live with the pain of my IC.

What do u do? March 14, 2012 at 3:35 am #41595Ellen Schnakenberg Participantshaneandnikkiredding – Don’t give up yet! It is likely that a reason your doctor doesn’t want you taking Fioricet is because of the very real chance you could end up with MOH (medication overuse headache).

Once you get in MOH you are in a really super tough spot. Patients in MOH are often noncompliant with treatment and continue to get worse and worse with time.

The doctor may want to help, but without a compliant patient they are left basically helpless to help you. This is very frustrating for the doctor and they tend to feel like hamsters running on a wheel in a cage. I know how vitally important the Elmiron is to your IC. I am first of all glad that it is helping.

I can’t help but wonder though, has your doctor ever given you bladder infusions to help with the IC and its associated pain? As bad as it sounds, I know a couple women who have had it done routinely with excellent results. Should something like that be effective, you may not have to take the Elmiron anymore.

There are many preventives that your doctor could try with you. Have you been on any in the past?

Have you ever tried a triptan or DHE? April 14, 2012 at 8:20 pm #41596Karen Participant I am on Fioricet (w/out codeine), and have found that while it does not help the pain itself…it does allow me to sleep when I am otherwise unable to do so because of the pain.

The pain is masked just enough…I do try to be cautious when using Fioricet, but have found that not only does it help me at night sleep with severe migraine pain, but if I am also having issues with my fibromyalgia and cannot sleep, I am able to find sweet relief in sleep after taking a Fioricet. It is far from being my first line of defense…but when nothing else is working, and I am despirate for sleep…well…April 26, 2012 at 5:16 pm #41597carladul Participant I must be in the minority.

I was first prescirbed fioricet 4 yrs ago and it was the only thing I had tried to date that helped with my migraines. I had to quit taking it 2 yrs ago due to insurance no longer covering it but was recently put back on it due the fact that all of the other meds I had tried in that time either didnt help at all or had very little effect on my full blown migraines.

I am also on Amerge which I find does help if I take it early enough. The problem there is I get 9 pills per month. You have to take the Amerge early on in the migraine and it is sometimes hard to tell what is the start of a migraine or just a really bad headache.

If I dont take the Amerge ealry enough it is nice to know that I have something to use as a backup if I need it. I dont find that fioricet makes me sleepy or unable to function. And as the mother of 4 that is a HUGE thing with me. April 27, 2012 at 4:46 pm #41598Teri Robert Participant Carladul,One way some of us can tell the difference between a Migraine and a headache is to hold on to something and bend over.

If bending over makes it worse, it’s most likely a Migraine. They’re exacerbated by physical activity. Sometimes, insurance companies will approve more doses of your triptan is your doctor sends them a litter and gets the prescription preapproved.

Have you checked into that? Teri April 28, 2012 at 9:18 pm #41599Anonymous Actually, it seems that though people may have migraine and tension type, the tension type is probably part of the migraine spectrum and it may be hard to tell what the difference is.

I tell my migraine patients to use migraine meds like Amerge even for a mild headache. But of course with good preventatives, etc one shouldn’t be worried about 9 per month limit.

Again, I think butalbital compounds like Fioricet should be pulled from the market. July 11, 2012 at 1:52 pm #41600zeenac Participant I have recently been taking Phrenilin, which I believe is Acetaminophen and Butalbital- no caffeine like Fioricet. So far it’s working pretty well with few side-effects. I’ve taken it about once a week for the past four weeks.

July 12, 2012 at 4:20 pm #41601Tiffanie Participant I take Fioricet with codeine and I find that it relieves the otherwise excruciating pain. To avoid MOH I only use it as a last resort medication. Which means I am at the point where nothing could be worse so it is worth the any risks. July 25, 2012 at 3:36 am #41602Achinghead Participant I was prescribed Fioricet with and without codeine by my pcp. Over time, I was getting more and more migraines, eventually getting migraines every day. I ended up having to go to a Headache Specialist who advised that my increasing use of Fioricet was indeed causing medication overuse headaches.

I had to go through a very long and painful 4 month period during which the only pain medication I could take for my daily migraines was Amerg no more than twice weekly. It was a difficult period, but I got through it and I learned my lesson. I destroyed my remaining Fioricet. I still take pain mediation only 2 and occasionally 3 days a week. I don’t ever want to experience medication overuse headaches again.

July 26, 2012 at 2:57 pm #41603Ellen Schnakenberg Participant ACHINGHEAD – I am SO terribly sorry you experienced this. I still cannot comprehend why physicians don’t educate their patients about MOH. This is one reason however, why as advocates, we try to really harp on patients to educate themselves about their conditions and their medications.

Doctors do not tell us everything we need to know. We can’t depend on them for that. That part must be our responsibility as patients.

February 27, 2013 at 5:18 pm #41605med1311Participant I have had migraines for over thirthy years. Have had every test imaginable and the only meds I now take is Fioricet, it is the only thing that lessens the attack and don’t know what I would do without it. Caution: Fiorinal actually gave me a bleeding ulcer! !February 28, 2013 at 1:41 am #41606Ellen Schnakenberg Participantmed1311 – I am glad that you have one thing that seems to help you.

However, your bleeding ulcer comment did concern me just a little. How often do you take your Fioricet? August 9, 2013 at 11:26 pm #44434Heidi Participant Besides MOH, why does everyone feel that Fioricet is so harmful?

Please educate me as I have to take it a few times a week due to chronic migraines. Nothing else has worked for me. I have chronic migraines and due to being sensitive to many drugs my neurologist stated that there wasn’t anything else I could take.

I’ve tried many different medications. And just to clarify, my neurologist did ask me to back off of Fioricet due to MOH but she also agreed that I didn’t have many other options. I would just like to know if there are any other reasons that Fioricet should not be taken. Thanks!August 10, 2013 at 7:48 pm #44439merrie Participant Hi, I am in a similar situation regarding meds, but unfortunately fioricet does not work for me anymore (never was that great). So I have stopped taking it unless I am desperate and feel like if I don’t at least try something I won’t make it.

(In other words, it more that I need to do something psychologically even if it doesn’t work). The biggest issue with fioricet other than MOH is that it just covers up the symptoms of a migraine, doesn’t make it go away. I have found that when I do that, whether with fioricet or some other pain reliever, the headache comes back as soon as the meds wear off more often than not.

Also, I have read of several people who have become addicted addicted to or dependant on fioricet, so it has those risks like any other pain med. Merrie August 11, 2013 at 12:10 pm #44450Nancy Harris Bonk Moderator Hi neugrey,Fioricet and other pain medications like it simply mask migraine pain – they do not abort it.

Stopping the migraine process is tops on the list of a good migraine treatment plan, covering up migraine pain is not. Now having said that fioricet and other pain medications can be used sparingly (no more than two to three times a week due to increased moh risk) as a rescue medication when our abortives fail.

The first line of treatment in migraine plan is prevention. The general rule of thumb is that if we have three or more severe migraine attacks a month we need to discuss migraine prevention medication with our doctor.

When we get an attack we use abortives such as the triptans (Imitrex, Maxalt and so on) or ergotamines like Migranal Nasal spray. If the abortives fail, then we use rescue medications like fioricet or others. Do you take a migraine preventive medication?

Let me share some information with you on the 7 Essentials of Migraine Management if you haven’t seen it yet. It is very helpful; https://migraine.com/blog/migraine-management-essentials/. Let me know what you think, Nancy August 11, 2013 at 12:15 pm #44453Nancy Harris Bonk Moderator You got it Merrie!Nancy August 13, 2013 at 4:20 am #44503Chris Hicks Participant Hello Everyone,After years with neurologists that specialize in treating migraine I have fully embraced the concept of rebound from overuse of abortive medications.

I don’t know how many people keep a migraine diary, but I do. In fact, I have built a spreadsheet in which I track not only my migraines but also, among other things, the abortive medications I take.

I have, in this spreadsheet, built in a some simple formulas that color code cells to let me know when I am approaching rebound territory. This visual cue helps me manage the balancing act of treating with abortives versus settling in to let the migraine run its course. With migraine as frequent as I have them there really is very little option other than letting some of these go untreated.

I would also say that, beyond rebound, it is a good idea to be very mindful and thoughtful about what you put into your body to treat the migraine. I know for me there was a time when I would simply grab some (or a handful) pills in an attempt to stop the pain.

It can be dangerous to mindlessly take pills. Thinking about rebound, tracking my abortive use in a spreadsheet or simply being mindful, these are some helpful techniques in this ongoing war against (chronic) migraine.

Take Care, Chris August 13, 2013 at 2:30 pm #44526Amy Babee Participant Butalbital didn’t work for me either. If it works for some people, Hurray! Anything to kill the throbbing brain-eating pain in the head. August 13, 2013 at 2:35 pm #44528Chris Hicks Participant Brain-eating pain… that’s where I am living today!!!!! !August 14, 2013 at 4:17 pm #44550Ellen Schnakenberg Participant Chris, congratulations on your uber management skills.

We also did the spreadsheet thing, complete with color coding. Added in triggers like weather/pressure levels etc. Ended up abandoning it as with time we got very good at managing without having to deal with sitting at the computer 10 times a day to enter things. There is a point at which journaling etc can get intrusive. If it’s helping you, at the very least it is also telling your doctor that you are serious about getting these things under control. At the worst it can make him/her think you’re obsessively compulsive about your Migraines, and even hysterically afraid of them. I’ve seen it go both ways, and there’s never a really good way to figure out which doc is going to react which way.

Keeping track of how you’re taking your meds is vitally important though. We don’t have a lot of control over our Migraines, but this is one part where we DO have some control!~Ellen August 28, 2013 at 12:52 pm #44825yaiyai789Participant No YOU ARE NOT THE ONLY ONE TAKING FIORICET, SOME DAYS I HAVE TO TAKE 6, ON THE DAYS OF 6 PILLS I HAVE TO TAKE 2 AT A TIME.

IT WORKS MOST OF THE TIME BUT I ALSO HAVE TO USE A TENS UNIT. HERE OF LATE I CAN’T GET RID OF MR. MIGRAINE.

I JUST WISH HE WOULD TAKE A VACATION. August 28, 2013 at 8:08 pm #44839Nancy Harris Bonk Moderator Hi yaiyai789,It’s unfortunate, but Fioricet is still being prescribed for migraines. The problem is taking migraine abortive medications and/or pain relievers (like Fioricet) whether they are over-the-counter or by prescription, more than two to three days a week, can increase our risk of a condition called medication overuse headache, or moh formerly called rebound.

If we have moh, we will continue to have unending daily head pain in a cycle that won’t end. And it makes our migraine attacks more difficult to treat. Please take a look at this information on moh to see how to end this vicious cycle; https://migraine.com/blog/help-how-can-i-not-overuse-migraine-medications/. Nancy August 29, 2013 at 11:25 am #44869yaiyai789Participant Hi Nancy Thanks for your answer on Fioricet.

I have always been afraid of taking to many of these along with other meds I have had to take or try to help with my migraines. After two days of having back to back BAD mirgaines and using my TENS unit instead of taking more pills I ended up taking sumatriptan 100mg.

At bed time. I don’t like taking these pills but I was beyond my point of pain. It takes a lot of pain for me to take them. I try everything like working outside, reading or doing something I really like to do . Taking special care of my therapy dog who will not leave my side during these days.

I will talk to my neurologist when I go in for my Botox injections about over use of the Fioricet. Thanks for the Heads Up on the use of the meds. P. S. I live a stressed life as a care giver for my husband. I feel sometimes this trigers my migraines along with the weather. But I keep on smilling. May 25, 2014 at 10:57 am #51205couldbeworse Participant The thing about Fioricet, for me, is that it makes my migraine days less miserable.

Not just becuase it relieves some of the muscle and joint pain, but because it makes me feel more positive and perky and energetic despite bottomed out serotonin levels.

I suppose some would judge me for enjoying the little bit of euphoria that comes from the barbituates. But my god, I’ve suffered from chronic migraines, and the negative mental state that comes with them, for almost 30 years. I don’t drink or smoke pot or do any other drugs (except for Imitrex). And I only take Fioricet during my 1-2 weeks of pms/menstruation/postms hell.

I’m a mom of 2 kids and own my own business and sometimes I just HAVE to function, despite the stupid migraines, muscle/joint pain and fatigue. Fioricet helps me stay (temporarily) functional. I had migraines for over 20 years before I was prescribed Fioricet (about 8 years ago).

And I occasionally go months without it to give my liver a break and reboot my system. I also like to try new, healthy things to eradicate my migraines, like avoid gluten and dairy or take magnesium or whatever (I never give up hope of curing this awful disease!). My pattern of head and muscle aches and fatigue are exactly the same with or without Fioricet – I just don’t have that little 4 hour boost to get some things done.

I recently had a new nurse at my doctor’s office give me a lecture about refilling my Fioricet every couple months (40 pills). She told me about new studies that had come out about the dependency risks and rebound headache potential. I said I’ve never had these problems, but is there something they could replace it with? She recommended I take ibuprofen instead.

Seriously. I have an ulcer from all the ibuprofen I’ve taken over the years, despite the fact that it barely does anything. I don’t have a drug problem. I have a chronic migraine problem. I’m not trying to diminish the issues some people have had with this drug. It’s really not one to trifle with. The benefits outweigh the risks for me personally, though. And until something better comes along, I don’t think it should be withheld from responsible migraine sufferers. June 12, 2014 at 5:14 pm #52138mygrainetoo Participant Carladul & Neugrey –I also found immediate & total relief with Fioricet.

As for my test for the ‘real migraine’: two aspirins with a cup of coffee, the move around (bend over, walk, hop, etc) & smell test (open containers in the fridge) & get into bright light & try to read – all for about 30 minutes before I take the Fioricet. I am taking a 50 mg Topamax at night & am supposed to add a 2nd pill next week to try to minimize use of Fioricet. I am so elated to have some life control back I can hardly stand it. A month ago I was having 2 -3 day migraines 4 – 8 times a month.

When they started I would try to think of everything I had planned for the next 3 days & quickly prioritize what I could do before I was bedridden & projectile vomiting.

July 21, 2014 at 10:27 pm #53133suzanneeileen Participant When it comes to treating chronic migraine, my first preference would be for my preventatives to work (currently, Amitriptyline and Botox). But since so far they aren’t helping all that much, my second preference is triptans (Maxalt and Relpax). My problem, however, is that the triptans make me a bit fuzzy. If it’s a work day, I try to work from home if possible so I can take the Maxalt.

But if I have to come into the office and look alert, I need an alternative. That’s where the fioricet comes in.

It doesn’t work as well as the triptans, but it can take the edge off and enable me to suck it up and fake being okay for whatever essential meeting dragged me into the office. My neurologist was reluctant to prescribe it, but we had a heart to heart chat about MOH, and I promised to try my best to keep my fioricet/triptan intake to as close to 3 days a week as I could.

As a result, I take fioricet at most once a week, and keep the triptans down to 3 days out of 7. No-drug days really suck, but I’ve had rebound headaches before, and they are truly awful. I think the main downside of my approach is that I’m hesitant to use my abortive drugs at the onset of a migraine, because I don’t want to waste a drug day if the migraine won’t be that bad.

Thus the triptans are never quite as effective as they could be. Haven’t figured that one out yet. July 22, 2014 at 10:58 pm #53153Anonymous Has your neurologist tried DHE and other formulations of NSAIDS?

July 23, 2014 at 3:06 pm #53182suzanneeileen Participant Haven’t tried DHE. A few years ago, I went a little overboard on Excedrin and my stomach revolted (severe bouts of acute gastritis) so my gut doctor said no more NSAIDs.

That’s when I started on fioricet. July 24, 2014 at 5:46 pm #53230Anonymous Technically you are in medication overuse with triptans more than 10 days a week as what you described above. Fioricet can contribute at 5 days a month July 25, 2014 at 1:52 pm #53234Anonymous I meant ten days a month above August 9, 2014 at 4:14 pm #54403Lindy Loo Participant I am so thankful for the insights of everyone here.

I feel blanket statements such as the Dr saying “Fioricet should be pulled from the market” is typical of Drs who do not see the patient as an individual. I have had migraines since the 1960s. Through the decades I have been a compliant (guinea pig) patient to 7 neurologists and countless Physicians.

(Including Dr J Saper and team). None of them, or the “next new thing” meds, ever helped, and most treatments I had severe negative reactions to. At 35-40 years old, my migraines became chronic and complicated. Still compliant and miserable. Then, when given (get ready to fall off your seats) a daily combination of Fioricet and Cafergot, I have a life!

I feel alive, I feel as if I am in control and I am not on my couch or bathroom floor every day. Why is my quality of life at risk of being pulled out from under me, because of MOH?

Take away these meds, and I am violently ill, in severe pain and incapable of living an enjoyable active life.

I just do not understand. We found what does work for me. I have not been to an ER in a decade and I don’t need MORE or run out. 3 Fioricet each day and 1/2 cafergot suppository. When not on these, I go right back to chronic daily HA/migraine.

Aren’t some uses unique? August 9, 2014 at 4:53 pm #54404Lindy Loo Participant Another question. When I was off from (and before I was taking) the Fioricet/Cafergot daily combo, I had 30 days of chronic Intractable Migraine per month. With all of the severe complications to treatments tried, and with other medical dxs, is MOH really a problem for me?

Because I am being helped and my quality of life is improved (greatly) while on the meds, and when off I was always severely sick.

I am in my 50s and don’t have any energy for going back to being a guinea pig again. I was near-suicidal when dealing with all of those side effects and no relief from the migraines. August 30, 2014 at 10:46 pm #55047Amy OTParticipant The discussion about Fioricet is very interesting, but also confusing.

I had to stop taking triptans recently due to a cardiac issue and my family practice dr. prescribed fioricet. If I have been taking 1 – 2 a day for about a week is there a danger of seizures/withdrawal if I stop “cold turkey” once this cycle of migraines stops?

August 30, 2014 at 11:03 pm #55049Amy OTParticipant Also, has anyone here had supraventricular tachycardia and a cardiac ablation?

I doubt if it’s related to migraines but who knows, maybe there is some connection. thanks~ and hope everyone is having a migraine-free/pain-free night September 1, 2014 at 8:44 pm #55066Katie M. Golden Moderator Amy OT, I just found a small study from 2014 that shows after a cardia ablation, patients with existing Migraines, showed less occurrences of Migraines after the procedure.http://content.onlinejacc.org/article.aspx?articleid=1856720-Katie September 1, 2014 at 8:50 pm #55067Amy OTParticipant Hi Katie, wow, thanks so much for finding and posting this.

It’s very interesting. Now I’m wondering if the slight reduction in migraines i’ve had is from the ablation or from going off the triptans, which might have been causing rebounds.

Thanks again! Amy September 2, 2014 at 1:45 pm #55092Anonymous To Lindy Loo:“I feel blanket statements such as the Dr saying ‘Fioricet should be pulled from the market’ is typical of Drs who do not see the patient as an individual.”—–I’m going to disagree with this statement as I say this all the time and I treat all my patients as individuals.“I just do not understand.

We found what does work for me. I have not been to an ER in a decade and I don’t need MORE or run out. 3 Fioricet each day and 1/2 cafergot suppository. When not on these, I go right back to chronic daily HA/migraine.

Aren’t some uses unique?”—–Yes, some cases are unique but in the majority there is a problem with MOH, especially Fioricet. Recent studies have shown that the changes that occur in the brain seen on functional MRIs in MOH patients can take MONTHS to clear.

I find that it can be WEEKS to clear MOH, especially with being on Fioricet for years. Clinically, it could take a long time for MOH to clear. It’s getting through the withdrawal phase that can drive patients (and myself) insane as often treatments will not work.

The problem would be if headaches increase AND/OR your Fioricet intake increases. That means it’s not working. I’m not saying what Dr. Saper is doing wrong as there are unique cases in some individuals; I just chose the path of no butalbital mixtures.

That’s how I was trained September 2, 2014 at 9:45 pm #55111Mary Butler Groom Participant I was recently at Mayo Clinic in MN. I was told to stop the Fioricet as it cause Medication Overuse and rebound headaches. September 3, 2014 at 8:51 pm #55168mygrainetoo Participant To Mary Butler Groom –What are you currently using in place of Fioricet and is it working as well, better, or not as well?

I hope you are a lot better after your visit to Mayo!November 14, 2014 at 3:36 pm #57427Emily Participant Hello Everyone,I am SO SO SO glad I found this forum on Fioricet.

I have been suffering from chronic, daily migraines for 4 months due to Depo-Provera injections. My neurologist put me on Depakote, 125mg (3x daily); Fioricet w/Codeine (2 pills every 4 hours as needed for migraine); Imitrex 100mg (1 pill at the beginning of a migraine or if my Fioricet doesn’t work).

I also take Promethazine, 12.5mg (1-2 pills every 6 hours for nausea during my migraines). I have to say.. the Fioricet w/Codeine has been a god send and my neurologist said I would more then likely get withdraw headaches or rebound headaches once I stop when the Depo runs out my system in about 2 months.

I have been taking Fioricet w/Codeine for about a month now. I usually take 2 a day because my migraines happen daily.

I saw a handful of people had great success taking Fioricet w/Codeine. Are the rebound headaches tolerable or is there another medication someone with daily migraines could suggest? I understand not having medical training, etc. But this is solely to get a better perspective on the treatments that are out there and to see how Fioricet w/Codeine has worked for others.

Thanks for reading!April 29, 2016 at 2:15 pm #74674j Participant I have been taking fiorinal with codeine for about 3 years. I’ve tried every abortive and preventative under the sun, and the fiorinal is the only thing that works for me. It gets rid of the pain, makes me functional, and prevents the 24 hour cyclic vomiting. I am very careful about my usage of it and only use it if absolutely necessary.

I was originally prescribed it by my first neurologist and then my pcp. I went to see a new neurologist because my headaches have become worse, and he pushed Botox on me and said he would not prescribe me the fiorinal anymore unless it was for “short periods of time.” He told me no headache specialist would prescribe fiorinal with codeine to me which I know is not true.

I also went to see my pcp because I didn’t like the neurologist and how he didn’t listen to me. She also refused to prescribe me fiorinal with codeine (after doing so for 1.5 years) and said we should try abortives I’ve already tried and failed with again.

I am at a loss for what to do and am having major anxiety about how to deal with an attack a. while I’m waiting for the Botox to be approved and b. if I get an attack while I am being treated with the Botox.

I understand the “dangers” of this type of drug but it truly is the only thing that has helped my chronic migraines after 20+ years of searching. Without it, I’m completely unable to function as I am bedridden – sometimes for days. April 29, 2016 at 2:59 pm #74680Katie M. Golden Moderator J, I can imagine how frustrating this is.

My headache specialists allows me to use percocet in small doses and it really helps me to be more functional. However it is not my first go-to abortive. Besides worrying about addiction, doctors are also concerned that using it too often can cause medication overuse headache.

Both of these make doctors skittish to prescribe these types of drugs. You mentioned that you’ve tried a lot of abortives and failed. Were they all Triptans like Maxalt, Imitrex, Treximet, etc? Have you ever tried DHE? Triptans stopped working for me and DHE has been helpful.

It is available in a shot form or as a nasal spray. Here’s some basic info on it. It’s a very old school medicine that’s being used more and more.

Ergotamines Clinical Efficacy and Safety Ergotamine and dihydroergotamine (DHE) are migraine-specific drugs that achieve their effect by binding to serotonergic receptors. [1, 2] Because of poor absorption and harsh side effects, oral ergotamine is generally not used. Ergotamine … Continue reading Migraine.com Word Press Embed HTML Embed Copy and paste this URL into your Word Press site to embed-Katie Migraine.com Moderator April 29, 2016 at 3:22 pm #74683j Participant I have tried DHE in the form of the nasal spray.

It is some help and sometimes prevents me from having to use the fiorinal. However sometimes it works for an hour and the migraine comes back. I’ve also reassured my doctor that I don’t use fiorinal as a first solution and I am cognizant of how many days a month I do use it.

April 29, 2016 at 3:54 pm #74698Jillian SModerator J, It is good to hear back from you. I am very sorry about your current situation and completely understand how anxious you must feel. You have found something that worked well for you and now you are unable to get it. That is very stressful!

At the same time, you have to believe that your doctors are looking out for your best interest. I know sometimes it can feel like you have tried EVERYTHING. I have felt that way many times. But there are hundreds of treatments out there and more coming out each year.

Personally, I have found Cambia to be an extremely effective abortive- I am unsure if you have tried that. When I am in too deep & cambia does not work I used nabumetone. As a last resort I will use a steroid which generally breaks a bad cycle. If you haven’t already, express your concerns to your doctors about what to do if you experience an attack while waiting or during botox.

If you find you are left empty handed, it might be worth getting another opinion. In the meantime, I wanted to share an article that I think you might be able to relate to: I’ve Tried Everything“I’ve tried everything.” These words get used often by Migraineurs.

I absolutely use this phrase as a defense mechanism. As soon as I share with someone that I suffer from Chronic Migraines, … Continue reading Migraine.com 16Word Press Embed HTML Embed Copy and paste this URL into your Word Press site to embed Here is another article regarding migraine research which I hope makes you feel a bit more hopeful: https://migraine.com/blog/finding-hope-in-migraine-research/Warmly, Jillian (Migraine.com Team)May 6, 2016 at 3:08 pm #75025leedyklaiber Participant I am currently receiving Botox injections every 2 months bc they did not last 12 weeks for me.

I was surprised to find that they were supposed to. Mine were so chronic that I felt as though I went for days without being able to hold my head up. The botox has brought the severity of my migraines down to a manageable level, however, I still have more migraine days than not.

My PCP will now only prescribe Fioricet and vicuprofen for my migraines and not that many. Oddly, the very same PCP will give my mother 180 Fiorinal w codeine for 3mo at a time.

She is in her 70s and does not have nearly the severity of migraines that I do. I am still willing to do whatever it takes to lessen these migraines.

I have a 16yo and I feel that I have let her down over the last three years or so as my headaches have worsened. At least now I can drop her off and pick her up from school, something that I had to rely on other moms to do at my worst. I find that Fioricet will take the edge off, but never stops a migraine. It is still lurking there waiting for 4 hours to end.

I was recently prescribed Zecuity to use when the menstrual migraines still confine me to bed. You get 4 patches for the month but can only use 2 for the same migraine. I’m apprehensive abt using it but I did have some success w Imitrex years ago. I just do not like to take drugs w/o knowing how I will react when I have to be somewhere or drive.

Sorry, I’m rambling, but I have had a migraine for 3 days and am just frustrated that the best I can do is to lessen the pain, not to mention everything else that goes with it.

May 8, 2016 at 5:08 pm #75070Jillian SModerator Leedyklaiber, Thank you very much for sharing your story with us. I am sorry to hear that you are still experiencing frequent migraines. When I was getting botox, I also felt that I could not hold my head up for the life of me!

I discussed this side effect with my neurologist and he stopped injecting as much in my neck which really helped. I have also tried Zecuity! It was definitely much different than any other medication I have taken only because it is transdermal. The medication that is in zecuity, sumatriptan, has never really been my go-to abortive even in the pill or injectable form.

I find that Cambia works better for me when I have an attack. Anyhow, the Zecuity lessened my pain a little bit and I had no negative side effects.

The only thing that I noted was that my skin was a little irritated after taking the patch off. Nothing crazy, just red dry skin.

If your doctor has prescribed it, I think it is definitely worth giving it a shot. Perhaps you can take it at night or when you have no obligation to go anywhere. My heart breaks for you to hear about how you feel like you let your daughter down. I understand how hard it can be but you have to remind yourself that all you can do is your best. Unfortunately, migraine is an incredibly debilitating disease and whether they want to or not, our family has to accept where we are at.

I wanted to share a few articles with you about migraine and parenting. If you are interested in feedback from other community members, be sure to check out the comments under each article!

-Migraine Doesn’t Make You a Bad Parent: https://migraine.com/?s=parent&submit=Go-Talking to Your Children About Migraine; https://migraine.com/blog/how-can-i-talk-to-my-children-about-migraine-part-1-my-migraine/-How Can I Keep Parenting During a Migraine? : https://migraine.com/blog/how-can-i-keep-parenting-during-a-migraine/I hope you find this information helpful.

We are here for any follow up questions, comments or concerns you might have. Best, Jillian (Migraine.com Team)May 18, 2016 at 1:08 am #75487Autumn Sparrow Participant Fioricet has been the only thing that’s helped break the pain for me over 10 years.

I have to take 4-12 per day as it doesn’t kill it. But as far as functioning it beats dilaudid which turns me into an invinceble 5 year old (mentally) it also keeps me up ( they think my receptors are flipped). July 29, 2016 at 12:31 pm #77669hamana Participant After 20 years of taking one to one and a half Fioricets a day along with one regular Tylinol, my GP suggested I see a neurologist for my almost daily headaches.

I’ve had almost daily headaches for 40 years (dull frontal tension types) with occasional migraines. The neurologist gave me a prescription for Topamax and offered me a week of Prednisone to help going off the Fioricet. Sorry, I said, I don’t want to bloat up and ruin what’s left of my osteopenia bones for nothing, so turned down the Prenisone and went cold turkey on my own.

I held off taking the Topamax for two reasons: 1. I was terrified after reading the mediocre ratings given for it online and the long horrible list of side effects, including BLINDNESS.

I had just been through cataract surgery and am 69 years old, so felt no thanks on risking THAT. 2. I was going to visit a friend for two days this week, which involved a 2 hour drive and didn’t want to risk trying a new med while driving.

The first 3 days after stopping the Fioricet, I had a pressure in my forehead but no real headache. The 4th day, the one visiting the friend, I had a headache all day, but took nothing and managed to even take a long walk in the hot sun during it.

Not pleasant but I managed. The next day it was better, though still there a little bit. When I got back from the trip, I took my first Topamax just to try it, but only half a pill before bed.

In the morning, I took the other half. I felt like a zombie. Drove to town to run errands and while in the bank, I literally didn’t feel like myself. Had I been taken over by aliens? Who knows? Not good. Came home and popped open a Diet Pepsi and it tasted flat. Got online and guess what – some people reported that while taking Topamax, they couldn’t taste carbonation!

WTH? I thought, I hate this drug. NOT taking it. So it is now one week after visiting the neurologist. I have not taken a Fioricet since and do not really have a headache now, though there is some feeling of pressure. I think I tense my head muscles, though this is not always the case. I have different types of headaches, they don’t all feel the same.

They are: off and on daily tension, bad tension (spoils my fun, so to speak), real migraine (sickening – definitely need a Fioricet and to sit down quietly and do nothing at all till it kicks in), and ocular (very rare – the flashing lights and no pain, lasts 20 minutes, just wait it out.

)What I would like to do now, since I know I can go without the Fioricet on a daily basis, is to use it only for a sickening migraine.

Since those last several hours, this might involve taking 2 or 3 over the day. Then I would return to taking none. I need to mention here that I cannot take aspirin, Aleve or any NSAIDS. They turn my stomach into an acid pit and/or give me the runs.

Miserable. Tylinol alone does not take away the headache. Only Fioricet works. So, my question if any doctors are reading this, is: why, to a neurologist, is it perfectly okay to take a horrible drug that can cause kidney stones, make you go blind and turn you into a zombie every day for the rest of your life but it’s not okay to take one Fioricet a day?

(not that I want to take it everyday anymore, but just asking – when I did take it like that, I had yearly or twice yearly blood tests and my liver and kidney function are good). This makes no sense to me. I can understand if I were taking 3 or more a day, but I don’t get taking one a day.

I’m afraid that now if I decide to continue on as I am (NOT taking it daily and just using it for a full scale migraine) that doctors will refuse to prescribe it for me.

At the moment, no problem, I have enough, but what if I live to 90? July 30, 2016 at 2:31 pm #77675Katie M. Golden Moderator@hamana, Thanks for the detailed description of what you experienced.

I’m not a doctor, but will try to share with you a few things about your story: 1. I’m glad you were able to go off of Fioricet. Taking them on a daily basis can cause rebound headaches, which is why you are likely having fewer Migraines now that you are off of it daily.

It’s great to take when you have a monster migraine to get through the pain, but daily use can cause some issues. Here’s info on rebound or medication overuse headaches: https://migraine.com/blog/migraine-narcotic-drugs-rebound-headaches/ 2. Topamax can be a very helpful drug to many who have migraine. You’ve discovered the laundry list of side effects, some being quite scary.

Not everyone will experience these. And if you start taking it and find the side effects overwhelming- talk to your doctor. What dose did you start out on? It’s very important to start low and then work up to a higher dose. Typically increasing in increments of 25mg at a time. I believe there is an increased risk for some side effects when you reach higher doses.

The max I typically see is 200mg, sometimes 300mg a day. You mentioned the first time you tried it, you took half a pill at night and half during the day. Ask your doctor, but I recommend taking it any dose only at night. It can make you sleepy and it can make you very confused, like you experienced.

Also sometimes switching to an extended release can alleviate some side effects. 3. In the end, topamax is not for everyone.

Follow your gut, but discuss with your doctor. There are other preventative medications that have less side effects and are more gentle on your body. Let me know if I can help at all. -Katie Migraine.com Moderator July 29, 2016 at 4:44 pm #77672Autumn Sparrow Participant Unfortunately like you fioricet is the only thing that helps me.

Recently my Neuro started making me pick up the RX slip and no refills (like it was a schedule 2 drug). I asked my pharmacist and he said there’s a lot of confusion over the scheduling of fioricet recently. So that might be one reason you’re Neuro is hesitant. As you probably know it also has acetaminophen which is a NSAID- they are finding out that NSAIDs are much worse than originally thought. Also taking most headache meds daily puts you at risk for medication overuse headache, but if that’s not how you’re using them it shouldn’t be an issue. I’ve had to go on anticonvulsants in the past for my migraines but like you stopped due to the side effects. My understanding is the pathology of migraines is similar to epilepsy. During my 2nd week of topamax I stopped being able to do basic addition & subtraction; so my Neuro switched me to depakote and made me promise I didn’t want kids. Eventually I got off it, as the stuff is really horrid. I think they are trying to help, but there aren’t any simple answers. Sometimes a dr just isn’t a good match, if that’s how you feel I’d look for another. Ultimately up to us as patients to do our research and make the choices that are best for us. Author Posts You must be a member to reply to this topic. Register Now! Already a member? Log in now to reply to this topic. Recommended Reading Chronic Migraine: The Body’s Slow Leak The Differences Among Us: What I Wish Others With Migraine Knew Migraine Frequencies: Exactly How Different Are They? When Migraine Whispers Poison in Your Ear Reader favorites Migraine Meals: What I Eat When I Feel Like I Can't Eat Debating When to Take Abortive Medications Sleep, Migraine, and Insomnia Update on the Cefaly Device (The Migraine Girl's Perspective)

acetaminophen/butalbital/caffeine/codeine systemic Brand names: Fioricet with Codeine, Phrenilin with Caffeine and Codeine Drug class (es): narcotic analgesic combinations Acetaminophen/butalbital/caffeine/codeine systemic is used in the treatment of: Headachea

Caffeine

Caffeine Important: The information below refers to medicines available in the United States that contain caffeine.

Medications containing caffeine:caffeine systemic Brand names: Vivarin, Caffedrine, Cafcit, Molie Drug class (es): CNS stimulants Caffeine systemic is used in the treatment of: Apnea of Prematurity Asthma Hypersomnia Multi-ingredient medications containing caffeine:acetaminophen/aluminum hydroxide/aspirin/caffeine/magnesium hydroxide systemic Drug class (es): analgesic combinations Acetaminophen/aluminum hydroxide/aspirin/caffeine/magnesium hydroxide systemic is used in the treatment of: Painacetaminophen/aspirin/caffeine systemic Brand names: Excedrin, Excedrin Migraine, Migraine Relief, Vanquish Drug class (es): analgesic combinations Acetaminophen/aspirin/caffeine systemic is used in the treatment of: Migraine Osteoarthritis Pain/Feveracetaminophen/aspirin/caffeine/salicylamide systemic Brand names: Painaid, Saleto, Levacet, Exaprin Drug class (es): analgesic combinations Acetaminophen/aspirin/caffeine/salicylamide systemic is used in the treatment of: Migraine Painacetaminophen/butalbital/caffeine systemic Brand names: Fioricet, Esgic, Capacet, Fiorpap Drug class (es): analgesic combinations Acetaminophen/butalbital/caffeine systemic is used in the treatment of: Headache

cetaminophen/caffeine systemic Brand names: Headache Relief, Excedrin Tension Headache, Excedrin Mild Headache, Valorin Extra Drug class (es): analgesic combinations Acetaminophen/caffeine systemic is used in the treatment of: Cold Symptoms Headache Osteoarthritis Pain Period Pain Sinusitisacetaminophen/caffeine/chlorpheniramine/hydrocodone/phenylephrine systemic Brand names: Hycomine Compound Drug class (es): upper respiratory combinations Acetaminophen/caffeine/chlorpheniramine/hydrocodone/phenylephrine systemic is used in the treatment of: Cold Symptoms Cough and Nasal Congestionacetaminophen/caffeine/chlorpheniramine/phenylpropanolamine systemic Brand names: Sinapils Drug class (es): upper respiratory combinationsacetaminophen/caffeine/dihydrocodeine systemic Brand names: Trezix, DHC Plus, Panlor SS, Panlor Drug class (es): narcotic analgesic combinations Acetaminophen/caffeine/dihydrocodeine systemic is used in the treatment of: Painacetaminophen/caffeine/guaifenesin/phenylephrine systemic Brand names: Emagrin Forte (old formulation) Drug class (es): upper respiratory combinationsacetaminophen/caffeine/isometheptene mucate systemic Brand names: Prodrin, Migra Ten, Migralam Drug class (es): analgesic combinations Acetaminophen/caffeine/isometheptene mucate systemic is used in the treatment of: Headacheacetaminophen/caffeine/magnesium salicylate systemic Brand names: Knee Relief Drug class (es): analgesic combinations Acetaminophen/caffeine/magnesium salicylate systemic is used in the treatment of: Muscle Painacetaminophen/caffeine/magnesium salicylate/phenyltoloxamine systemic Brand names: Combiflex ES, Durabac Forte, Cafgesic Forte Drug class (es): analgesic combinations Acetaminophen/caffeine/magnesium salicylate/phenyltoloxamine systemic is used in the treatment of: Painacetaminophen/caffeine/phenylpropanolamine/salicylamide systemic Brand names: Saleto-D Drug class (es): upper respiratory combinationsacetaminophen/caffeine/phenyltoloxamine systemic Brand names: Flextra, Flextra Plus Drug class (es): analgesic combinations Acetaminophen/caffeine/phenyltoloxamine systemic is used in the treatment of: Cold Symptoms Headache Pain Sinusitisacetaminophen/caffeine/phenyltoloxamine/salicylamide systemic Brand names: Combiflex, Cafgesic, Durabac Drug class (es): analgesic combinations Acetaminophen/caffeine/phenyltoloxamine/salicylamide systemic is used in the treatment of: Painacetaminophen/caffeine/pyrilamine systemic Brand names: Menstrual Relief, Menstrual Relief Extra Strength, Menstrual Relief Maximum Strength, Midol Complete Drug class (es): analgesic combinations Acetaminophen/caffeine/pyrilamine systemic is used in the treatment of: Premenstrual Dysphoric Disorder Premenstrual Syndromeacetaminophen/caffeine/salicylamide systemic Brand names: Rid-A-Pain Compoundaspirin/butalbital/caffeine systemic Brand names: Butalbital Compound, Fiorinal, Fortabs, Fiormor Drug class (es): analgesic combinations Aspirin/butalbital/caffeine systemic is used in the treatment of: Headache Migraine Painaspirin/butalbital/caffeine/codeine systemic Brand names: Fiorinal with Codeine, Ascomp with Codeine, Fiorinal with Codeine III, Fiortal with Codeine Drug class (es): narcotic analgesic combinations Aspirin/butalbital/caffeine/codeine systemic is used in the treatment of: Headacheaspirin/caffeine systemic Brand names: Anacin, Bayer Back & Body, BC, Midol Traditional Drug class (es): analgesic combinations Aspirin/caffeine systemic is used in the treatment of: Fever Hangover Painaspirin/caffeine/dihydrocodeine systemic Brand names: Synalgos-DC Drug class (es): narcotic analgesic combinations Aspirin/caffeine/dihydrocodeine systemic is used in the treatment of: Painaspirin/caffeine/orphenadrine systemic Brand names: Norgesic, Orphengesic, Norgesic Forte, Orphengesic Forte Drug class (es): skeletal muscle relaxant combinations Aspirin/caffeine/orphenadrine systemic is used in the treatment of: Muscle Pain Muscle Spasmaspirin/caffeine/propoxyphene systemic Brand names: Propoxyphene Compound 65, PC-CAP, Darvon Compound 32, Darvon Compound-65 Drug class (es): narcotic analgesic combinations Aspirin/caffeine/propoxyphene systemic is used in the treatment of: Painaspirin/caffeine/salicylamide systemic Brand names: BC Fast Pain Relief, BC Headache, B C Powder, B C Powder Arthritis Strength Drug class (es): analgesic combinations Aspirin/caffeine/salicylamide systemic is used in the treatment of: Fever Headache Muscle Pain Painbelladonna/caffeine/ergotamine/pentobarbital systemic Brand names: Belcomp-PB, Cafatine PB, Micomp-PB, Ergocomp-PB Drug class (es): antimigraine agents Belladonna/caffeine/ergotamine/pentobarbital systemic is used in the treatment of: Migrainecaffeine/choline salicylate systemic Caffeine/choline salicylate systemic is used in the treatment of: Hangovercaffeine/ergotamine systemic Brand names: Cafergot, Cafatine, Cafetrate, Migergot Drug class (es): antimigraine agents Caffeine/ergotamine systemic is used in the treatment of: Cluster Headaches Migrainecaffeine/magnesium salicylate systemic Brand names: Diurex Drug class (es): analgesic combinations Caffeine/magnesium salicylate systemic is used in the treatment of: Period Paincaffeine/pheniramine/phenylephrine/sodium citrate/sodium salicylate systemic Brand names: Scot-Tussin Original (old formulation) Drug class (es): upper respiratory combinationscaffeine/sodium benzoate systemic Drug class (es): CNS stimulants Caffeine/sodium benzoate systemic is used in the treatment of: Respiratory Failure See Also→ Search the entire Drugs.com site for caffeine Disclaimer: The indications, uses and warnings for individual medications outside the USA are determined by local regulatory bodies in each country or region.

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ts. The aspirin to butalbital ratio in Fiorinal: 325 mg Aspirin / 50 mg Butalbital 97 mg Aspirin to 15 mg Butalbital (To be exempt, ration requires at least 188 mg or more Aspirin for every 15 mg Butalbital included in formulation. Therefore Fiorinal is classified as a Schedule III substance.

Fiorinal is a Schedule III controlled drug but Fioricet is not !

Fiorinal is a Schedule III controlled drug but Fioricet is not !Aug272013Tags: Fiorinal is a Schedule III controlled drug but Fioricet is not!Fioricet contains: 325 mg of acetaminophen (APAP), 50 mg of butalbital, and 40 mg of caffeine. New capsule reformulation of Fioricet contains: 300 mg of acetaminophen (APAP), 50 mg of butalbital, and 40 mg of caffeine.

Fiorinal contains: 325 mg of aspirin (ASA), 50 mg of butalbital, and 40 mg of caffeine. The only difference between these two is the aspirin in Fiorinal vs acetaminophen in Fioricet. The interesting thing is that Fiorinal is a scheduled class III substance, while Fioricet has a non-scheduled status.

It seems really strange because both combinations contain equal amount of the controlled substance butalbital. Exceptions from the scheduling have been made if the drug meets the requirements of section 811 (g) (3) (A) of the Controlled Substances Act. The exemption requires that one of the active ingredients be a non-narcotic controlled substance and one of the others be a non-scheduled compound.

The potential for abuse is decreased if a sufficient amount of a non-controlled substance (e.g., aspirin or acetaminophen) is added. According to the FDA, the issue boils down to a specific ratio of aspirin or acetaminophen to butalbital. Fiorinal® is required to have at least 188 mg of aspirin for every 15 mg of butalbital (188:15) to meet CSA exemption.

The ratio needed for Fioricet® is 70 mg of acetaminophen for every 15 mg of butalbital (70:15). These ratios were based on what the FDA believed were adequate amounts of nonnarcotic to reduce the abuse potential of butalbital. The acetaminophen to butalbital ratio in new and old formulation of Fioricet: Old formulation: 325 mg Acetaminophen / 50 mg Butalbital 97 mg Acetaminophen to 15 mg Butalbital (To be exempt, ration requires at least 70 mg or more Acetaminophen for every 15 mg Butalbital included in formulation.

New Formulation: 300 mg Acetaminophen / 50 mg Butalbital 90 mg Acetaminophen to 15 mg Butalbital (To be exempt, ration requires at least 70 mg or more Acetaminophen for every 15 mg Butalbital included in formulation. So both new and old formulation of Fioricet by law shall be exempt from controlled substance requiremen

Citation: 1. Section 811 (g) (3) (A) Controlled Substances Act 2. http://www.deadiversion.usdoj.gov/schedules/exempt/exempt_rx_list.pdf 3. http://www.communitymedical.org/sites/default/files/library/files/2014_04_physicians_edition.pdf **Please note: Under the following states law, Fioricet is classified as a Schedule III controlled drug. **Georgia Maryland New Mexico Utah Illinois Rhode Island West Virginiatop | previous page | | | | RSS | print

Caffeine can be good for headaches. The caffeine can help to open up and relax your muscles which can help relieve minor headaches. It's not much help for migraines though.

Is caffeine good for headaches?

"Health Other - Health Is caffeine good for headaches? I have heard yes and no. What do you think? I know that ""headache medicine""s such as Excedrin have caffeine in them, but then I heard that caffeine is bad for headaches and that it makes them worst...

I'm confused. :- (Follow 16 answers Answers Relevance Rating Newest Oldest Best Answer: It depends on the type of headache you have, what caused the headache, what kind of caffeine you're planning to drink to get rid of it (have sugar in it?) and also if you have a caffeine addiction to start with. Certain kind of headaches are helped in different ways.

Everyone is different also. Try to see what works for you; but caffeine won't (usually) have a huge positive or negative impact on a headache.schdor.list · 8 years ago0 0 Comment Asker's rating Is Caffeine Good For Headaches Source (s):https://shrinks.im/a80Dd?

· 1 year ago0 0 Commentyes people caffeine makes headaches worse.....thats why caffeine is in SO many pain relievers and it has nothing with do with relaxing the muscles whoever said that is wrong.

Also is works a treat for migraines also whoever said that was wrong. During a migraine headache your blood vessels are dilated (bigger) which makes your head ache a whole lot, caffeine works by constricting blood vessels (making them smaller) therefore pretty much eliminating a headache, i have a frequent migraines and i dont even use medicine anymore i just drink a coffee lol Kyle H · 8 years ago0 0 Comment Caffeine can help headaches but also can cause headaches, mainly in people who have a huge caffeine intake daily, when their body detects the caffeine levels drop they start to get a headache.

I can turn into a cycle but for the occasional headache relief it is a great help. Source (s):doctor visit B · 8 years ago0 0 Comment Is Caffeine Good For Migraines Source (s):https://shrink.im/ba G5e? · 2 years ago0 0 Comment

Anonymous · 8 years ago1 0 Comment Fast To Relieve Your Headache. Source (s):https://tinyurl.im/a HNox? · 2 years ago0 0 Comment Discover The Secret To Completely Eliminating Your Migraine Pain Forever In The Next 48 Hours & Never Spend Another Dime On Expensive, Dangerous Treatments - http://themigrainerelief.info/naturally-213.html You'll learn inside: +) The most common migraine triggers & how to avoid them, so that you can live a pain-free life.

+) Understand the root causes of a migraine headache which helps to prevent migraines forever. +) The most common food related triggers to help prevent migraines so that you can enjoy eating the foods you like.

+) Get rid of your migraine and cure your headache +) And much more useful information ... You can feel good again, no more depression or anxiety.

Start feeling good in just a few minutes. Overcome the pain of migraines with 3 simple but effective techniques to stop the migraine before it stops you from having fun. If you want to take control of my migraines and enjoy a pain-free life! Don't live another day with the pain and tortue of Migraines.

Act Now! - http://themigrainerelief.info/naturally-213.html You don't have to live another day with pain, discomfort or depression get rid of you're migraine headaches, remember that the problem CAN be prevented, controlled and treated, but ONLY if you take action today.

Source (s): The Migraine Relief System offering you everything you need to relieve, treat and prevent migraines - http://themigrainerelief.info/naturally-213.html Anonymous · 4 years ago0 0 Commenti drink a few mouthfuls of pepsi max for headaches.. it works wonders..

I never drink fizzy drinks as a rule and never have caffeine drinks.. but for a headache I always keep some handy.. some headaches can be caused through poor digestion and something in pepsi max helps that in me.. am looking for healthy alternatives, maybe digestive enzymes, but have yet to try..?

· 3 years ago0 0 Comment Yes, caffeine helps very good with headaches. buy some pepsi MAX (with extra caffeine) it always works for me.. a good'n'tasty medicine : D? · 8 years ago2 1 Comment1 2 next Maybe you would like to learn more about one of these? Time for a Caribbean cruise? Rheumatoid Arthritis Symptoms? Need an electronic signature? Interested in Life Alert? "

Combination or cocktail drugs that contain a combination of caffeine, acetaminophen, and aspirin (or alternatively, caffeine, acetaminophen, and ibuprofen) are often marketed as relief from migraines and tension headaches. Excedrin, one brand name of the type, is a combination of caffeine, acetaminophen, and aspirin.

What's the Difference Between Pain Relievers? Should I Buy Generic?

"What's the Difference Between Pain Relievers? Should I Buy Generic? Alan Henry6/12/13 11:00am Filed to: ask lifehacker 141 11Dear Lifehacker, Every time I go to the pharmacy, I'm confused. What's the difference between something like Tylenol and Advil? When should I use each one? What about sleep aids or cough medicines? Are generics okay, or should I spring for the brand name instead? Sincerely, Brand Skeptic Dear Brand Skeptic, The names and ingredients in common over-the-counter pain relievers and cold remedies can be confusing, so we don't blame you for asking.

To break down the language and figure out whether there are any real differences between brand names and generics, we sat down with Dr. Daniel Weiswasser, a board-certified internist and pediatrician who's been in outpatient practice in Western Massachusetts for nine years.

He's seen the brand names and the generics in action, and offered his expertise to the subject. Which Pain Reliever Should I Use, and When? Although many people have their own method of choosing what pain reliever to take when, there's no cheat sheet for ""use ibuprofen for x and y symptoms, and use acetaminophen or a and b symptoms.""

The real answer is that the most popular pain relievers are so similar that it doesn't matter, as long as you're using something that doesn't react badly with medication you're taking, affect a condition you already have (like high blood pressure or liver disease), and as long as you don't take too much. The most popular pain relievers boil down to two families: ibuprofen/naproxen and acetaminophen. We'll get into each one in a moment, but both have their own pros and cons.

In most cases, a doctor will tell you to try ibuprofen first (or naproxen if you want something longer lasting), and if there's an issue with it or there's a specific reason you should take acetaminophen, take that instead.

Here's why. Common Pain Medications and Their Brand Names When you hit the grocery store to pick up something to soothe a throbbing headache or pulled muscle, you have tons of options.

You might have a favorite, but if you're confused by terms like naproxen sodium or acetaminophen, here's a quick rundown of the most popular painkillers and their branded names. Obviously, these basics will help, but if you have any questions about which medication is right for you, don't hesitate to ask a medical professional who can assess your individual situation.

Aspirin Aspirin, also known as acetylsalicylic acid (ASA), is widely available as a generic (sometimes called ASA, other times just Aspirin), and the active ingredient in brand names like Bayer, Ecotrin, Fasprin, and Anacin (Aspirin with caffeine added).

It used to be popular for aches and pains, but as Dr. Weiswasser notes, Aspirin is rarely used for that at all anymore, in favor or more modern pain relievers: I would point out that aspirin is typically not used for pain relief anymore; it's used more typically for its platelet inhibition, which leads to thinning of the blood, which is thought to reduce the risk of heart attacks in those who have had heart attacks already in the past (also known as ""secondary prevention"").

While many use aspirin to prevent heart attacks in the first place (""primary prevention""), there is some new data that aspirin increases the risk of a certain eye disease, macular degeneration, so the use of it for primary prevention is being called into question. ( See this study in the Journal of the American Medical Association (JAMA) Internal Medicine) There's also some recent data suggesting that routine aspirin use reduces the risk of some solid cancers, like colon cancer.

( See this study in The Lancet. )Ibuprofen Ibuprofen is an NSAID (Non-Steroidal Anti-Inflammatory Drug) pain reliever, is generally considered the best and most accessible for most day-to-day aches and pains.

It's also used to bring down a fever. It's also an anti-inflammatory, meaning it reduces swelling. It too is widely sold as a generic just called ""ibuprofen,"" but it's also the active ingredient in Advil, Motrin, Midol, Nurofen, Nufren, Caldolor, Neo Profen, Ibu and the original, Brufen. Most doses usually last 4-6 hours. Ibuprofen (and really, any NSAID pain reliever) is not without side effects though.

Dr. Weiswasser explains: NSAID side effects include stomach upset and ulcers. Like their cousin, aspirin, they also inhibit platelet action, although to a lesser degree. They interfere with the cardioprotective effect of aspirin, may exacerbate heart failure, and may raise blood pressure. They can also worsen kidney disease. Naproxen Naproxen is, by comparison, new to the party. It's available as a generic (Naproxen Sodium), but depending on where you live, it might be prescription-only. You may know it as Aleve, Anaprox, Antalgin, Apranax, Feminax Ultra, Flanax, Inza, Midol Extended Relief, Nalgesin, Naposin, Naprelan, Naprogesic, or Naprosyn.

It's an NSAID, like ibuprofen, what means it offers the benefits (and risks) that ibuprofen does. The major difference though is that it lasts much longer. Dr. Weiswasser explains: Without getting too technical, the only real difference between ibuprofen and naproxen is that naproxen has a longer half-life, i.e. it lasts longer. Specifically, naproxen's analgesic effects last about 7 hours whereas ibuprofen's are about 4-6 hours.

The advice is typically that ibuprofen be taken no more than every 6 hours and naproxen no more than every 8-12 hours. So, if you need long-lasting pain relief, or don't want to pop ibuprofen every 6-8 hours, try naproxen. Acetaminophen (Paracetamol)Acetaminophen is a mild pain reliever, used for more minor aches and pains, and as a pain reliever in combination with other drugs.

It's available as a generic under its own name, and is the active ingredient in brand names like Tylenol, Panadol, Anacin-3 (or Anacin Aspirin Free), Acamol, Tempra, Datril, Feverall, and Ofirmev, among others. You'll also find it in cough and cold remedies, used to soothe aches and pains while you get over a bad cough or runny nose.

It's not an NSAID, so while it has similar pain relieving properties, it doesn't have anti-swelling properties, although it is often used to bring down a fever. However, Dr. Weiswasser reminded us that acetaminophen overuse is the most common cause of acute liver failure in the United States, and it's important never to exceed the recommended dose.

People who drink or have liver problems should avoid it entirely. In general, Acetaminophen is ideal for people who don't need anti-swelling, who want to avoid the side effects of NSAIDs, or for whom NSAIDs don't work as well. Combination Drugs (Like Excedrin)

Combination or cocktail drugs that contain a combination of caffeine, acetaminophen, and aspirin (or alternatively, caffeine, acetaminophen, and ibuprofen) are often marketed as relief from migraines and tension headaches. Excedrin, one brand name of the type, is a combination of caffeine, acetaminophen, and aspirin.

Generic ""migraine medications"" sold over the counter offer similar combinations, and when we asked Dr. Weiswasser about them, he noted that there's nothing about Excedrin or any other cocktail brand that's special that you couldn't make at home with the appropriate combination doses of their component pain relievers along with a strong cup of coffee.

That said, there's something to paying for the convenience of a pill, especially if you already have a headache and the last thing you want to do is the math to make sure you're not taking too much of any one component drug.

Keep in mind however that because these combination drugs contain acetaminophen, aspirin, and/or ibuprofen, they come with the side effects and risks of each when taken improperly.

Always follow the instructions on the label, and see a medical professional if you're tempted to do otherwise. Generic vs. Brand Name Drugs So now that you know what you want, which brand should you buy? That's pretty easy: Since all of these are available as generics, there's no reason to buy marketed brand names over their more affordable generics.

Some brand names offer different tablet styles, like liqui-gels or gel-capsules (which can be absorbed more rapidly than tablets), and others coat their pills with sugar, add caffeine, or add other inactive ingredients. You'll have to decide whether those features are worth your money. As for the active ingredients, there's no difference between brand name and generic. We'd say save your money. What About Other Over-the-Counter Medicines? Sleep Aids Sleep aids can be even more confusing than pain relievers, mostly because their active ingredients are harder to say, more mysterious, and the generic versions are rarely marketed with their actual pharmacological names.

The language barrier makes this a tricky issue, because people who would never buy brand name ibuprofen will make sure to pick up ZZZQuil over anything else, or swear by Unisom to help them fall asleep.

There are two major groups of over-the-counter sleep aids: Diphenhydramine, a strong sedating antihistamine, or in other words the ingredient in Benadryl or ZZZQuil that tends to make you so sleepy. It's still an antihistamine though, which also makes it an active ingredient in many allergy medications.

You'll find this marketed as a sleep medication as a generic (but you'll have to flip over the package to see it), and as the active ingredient in ZZZQuil, Unisom, and Sominex. Doxylamine is another antihistiamine. It's a short term sedative, and while diphenhydramine is the active ingredient in ZZZQuil, it's actually doxylamine that's in the original Ny Quil. It's also available as a generic, sometimes side by side with diphenhydramine. It's even more confusing because Unisom uses doxylamine as an active ingredient in one formulation, but not the other.

You could go to the pharmacy right now and find both, side by side on the same shelf, both labeled ""Unisom."" They may be different colors or in slightly different packages, but they'll be there. Both medications can help you get to sleep, but to say they ""treat insomnia"" is a stretch.

Dr. Weiswasser explains, and offers some alternatives: According to most research, diphenhydramine does not improve insomnia, and it may cause sedation the next day (due to its long half-life). It can also lead to delirium, dry mouth, blurred vision, urinary retention, and constipation. [Ed note: You can read more about these side effects here for diphenhydramine and here for doxylamine .]

Some people use the herbal product valerian, which also has virtually no better impact than placebo, and it can injure your liver. Melatonin can be helpful for some and is generally well tolerated, so that may be worth a try. Because, like all herbals, it's not under FDA regulation, however, you can never really be sure exactly what you're getting.

Finally, it's worth noting that many people try to treat their sleep problems with alcohol, but alcohol-induced sleep is of poor quality and increases the presence of sleep apnea.

Of course, you might also be hung-over the next day and can become dependent upon it. If you choose to take a sleep aid, sticking to the label is extremely important, and if you're taking them to alleviate chronic insomnia, stop and see a professional.

If your issue is poor sleep hygiene, we have some tips that can help. How to Get Better Sleep (and Need Less Every Night)Many of us struggle to get enough sleep every night, but is the sleep we get any good? While it’s…Read more Should buy the brand name, as in Unisom over the generic store-brand doxylamine succinate? No—like with pain relievers, there's little to no difference at all between them. There may be some inactive ingredients or formulations that make the sleep aid easier to absorb, but again, nothing that's really worth the extra money, especially not in this case.

Cough and Cold Medicines Much like sleep aids, many people will swear by Sudafed over the generic brand because they have anecdotal experience with the name. In reality, the difference is almost always perceived (for example, if the active ingredient in both is pseudoephedrine, there's no difference).

When we asked about other medications people may be confused about, like cough and cold remedies, Dr. Weiswasser reminds us that regardless of the the medication we're looking to take, it's critical to read the label: This is getting at a broader issue, which is that people should pay attention to ""active ingredients"" on labels and not brand names.

Although people will swear otherwise, there should be no difference between the guaifenesin (which loosens phlegm) in Robitussin Chest Congestion or in the non-name brand version. Same for pseudoephedrine / phenylephrine (decongestants) and dextromethorphan (cough suppressant). Some of these medications are, however, formulated for more extended release, which can be an advantage, especially when trying to sleep. Always Read the Label So the next time you're standing in the cough and cold aisle with a sniffly nose, wondering if Robitussin Chest Congestion or Mucinex is the better option, flip the labels over and read the active ingredients.

You'll find they're both guaifenesin, and should feel comfortable reaching for the generic. Robitussin (and many other brands) are well known for using different decongestants for different formulations, so always read the label for the type appropriate for your condition, make note of the active ingredient, then consider the generics.

This rule applies to cough and cold remedies, antacids and stomach relief medicines, laxatives, antidiarrheals, just about everything available over the counter.

Like Dr. Weiswasser noted, the only real reason you may want to consider one brand over another, or a brand name over a generic, is because one of them is available in a form or formula that's easier to absorb and offers quick relief, has an active ingredient that doesn't interact with a medication you're taking or a condition you have, or if your doctor suggests one over another.

Otherwise, save your money, buy generic, and read the label. Dr. Daniel Weiswasser is a board-certified internist and pediatrician who's been in outpatient practice in Western Massachusetts for nine years.

He offered his expertise with this feature, and we thank him. Photos by Robert Kneschke (Shutterstock), Iakov Filimonov (Shutterstock), Sage Ross, Matt Robinson, Quinn Dombrowski, Zack Mccarthy, Michelle Tribe, Eleanor Ryan, and Adam Hertz. "

), butalbital/acetaminophen/caffeine (Esgic, Fioricet), butalbital/aspirin/caffeine (Fiorinal Ascomp, Fortabs), butabarbital (Butisol), amobarbital (Amytal), pentobarbital (Nembutal), and secobarbital (Seconal). Side effects, drug interactions, dosage, storage, and pregnancy safety should be reviewed prior to taking this medication.

butalbital/acetaminophen/caffeine (Esgic, Fioricet)

"The display and use of drug information on this site is subject to express terms of use. By continuing to view the drug information, you agree to abide by such terms of use. GENERIC NAME: BUTALBITAL/ACETAMINOPHEN/CAFFEINE - ORAL (bue-TAL-bi-tal/a-SEET-a-MIN-oh-fen/KAF-een)BRAND NAME (S): Esgic, Fioricet Warning | Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage WARNING: One ingredient in this product is acetaminophen.

Taking too much acetaminophen may cause serious (possibly fatal) liver disease. Adults should not take more than 4000 milligrams (4 grams) of acetaminophen a day. If you have liver problems, consult your doctor or pharmacist for a safe dosage of this medication. Daily use of alcohol, especially when combined with acetaminophen, may increase your risk for liver damage.

Avoid alcohol. Check with your doctor or pharmacist for more information. Get medical help right away if you have any symptoms of liver damage, including: dark urine, persistent nausea / vomiting, stomach/ abdominal pain, extreme tiredness, or yellowing eyes/skin. Acetaminophen is an ingredient found in many nonprescription products and in some combination prescription medications (such as pain / fever drugs or cough -and- cold products). Carefully check the labels on all your medicines because they may also contain acetaminophen. Ask your pharmacist about using those products safely.

Get medical help right away if you have taken more than 4000 milligrams of acetaminophen a day, even if you feel well. Quick Guide Chronic Pain Syndrome: Treatment and Management for CPSUSES: This combination medication is used to treat tension headaches. Acetaminophen helps to decrease the pain from the headache. Caffeine helps increase the effects of acetaminophen.

Butalbital is a sedative that helps to decrease anxiety and cause sleepiness and relaxation. OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional.

Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. This medication may also be used to treat migraine headaches. HOW TO USE: See also Warning section.

Take this medication by mouth with or without food as directed by your doctor, usually every 4 hours as needed. If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon.

Do not use a household spoon because you may not get the correct dose. The dosage is based on your medical condition, age, and response to treatment. This medication works best if it is used as the first signs of a headache occur. If you wait until the headache has worsened, the medication may not work as well.

This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. In such cases, withdrawal symptoms (such as nausea / vomiting, mental/mood changes, seizures) may occur if you suddenly stop using this medication.

To prevent withdrawal reactions, your doctor may reduce your dose gradually. Report any withdrawal reactions immediately. Along with its benefits, this medication may rarely cause abnormal drug-seeking behavior ( addiction ). This risk may be increased if you have abused alcohol or drugs in the past. Take this medication exactly as prescribed to lessen the risk of addiction.

Tell your doctor if you notice increased use of this medication, a worsening of headaches, an increase in the number of headaches, the medication not working as well, or use of this medication for more than 2 headache episodes a week.

Do not take more than recommended. Your doctor may need to change your medication and/or add a separate medication to prevent the headaches. Surprising Reasons You're in Pain Slideshow Take the Pain Quiz Joint-Friendly Exercises to Reduce RA Pain Slideshow SIDE EFFECTS: See also Warning section.

Nausea, vomiting, abdominal pain, shaking (tremor), shortness of breath, increased urination, lightheadedness, dizziness, drowsiness, or trouble sleeping may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. To reduce your risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if any of these unlikely but serious side effects occur: mental/mood changes, fainting, seizures, fast/irregular heartbeat.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching /swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing . This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: See also Warning section. Before taking this medication, tell your doctor or pharmacist if you are allergic to acetaminophen, caffeine, or butalbital; or to other barbiturates (such as phenobarbital) or xanthine derivatives (such as theophylline ); or if you have any other allergies.

This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: severe breathing problems (such as bronchopneumonia), a certain enzyme disorder ( porphyria ), liver disease, kidney disease, personal or family history of regular use/abuse of drugs/alcohol, mental/mood disorders, abdominal/stomach problems (such as stomach ulcer ).

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages . Liquid products may contain alcohol, sugar and/or aspartame. Caution is advised if you have diabetes, alcohol dependence, liver disease, phenylketonuria (PKU), or any other condition that requires you to limit/avoid these substances in your diet.

Ask your doctor or pharmacist about using this product safely. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Older adults may be more sensitive to the side effects of this drug, especially drowsiness and trouble falling asleep. These side effects can increase the risk of falling. During pregnancy, this medication should be used only when clearly needed.

Using it for long periods or in high doses near the expected delivery date is not recommended because of possible harm to the unborn baby. Discuss the risks and benefits with your doctor. Infants born to mothers who have used this medication for an extended time may have withdrawal symptoms such as irritability, abnormal/persistent crying, vomiting, seizures, or diarrhea.

Tell your doctor immediately if you notice any of these symptoms in your newborn . This drug passes into breast milk and could have undesirable effects on a nursing infant. Consult your doctor before breast-feeding. From Tips to Better Manage Your Migraine Start Now DRUG INTERACTIONS: See also Warning section. Drug interactions may change how your medications work or increase your risk for serious side effects.

This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist.

Do not start, stop, or change the dosage of any medicines without your doctor's approval. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: sodium oxybate, drugs affecting liver enzymes that remove this medication from your body (such as macrolide antibiotics including erythromycin, cimetidine, disulfiram, valproic acid, fluvoxamine, MAO inhibitors including isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine), isoniazid, lithium, phenothiazines (such as chlorpromazine ). This drug can speed up the removal of other drugs from your body by affecting certain liver enzymes. These affected drugs include ""blood thinners"" (such as warfarin ), cyclosporine, doxycycline, estrogen, felodipine, metronidazole, quinidine, theophylline, certain beta blockers such as metoprolol, corticosteroids such as prednisone .

Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as certain antihistamines (such as diphenhydramine ), anti- seizure drugs (such as carbamazepine ), medicine for sleep or anxiety (such as alprazolam, diazepam, zolpidem ), muscle relaxants, narcotic pain relievers (such as codeine ), psychiatric medicines (such as risperidone, amitriptyline, trazodone ). Check the labels on all your medicines (such as cough -and-cold products) because they may contain caffeine or drowsiness-causing ingredients.

Also keep in mind that certain beverages (such as coffee, colas, tea, energy drinks) contain caffeine. Ask your pharmacist about using those products safely. This medication may decrease the effectiveness of hormonal birth control such as pills, patch, or ring. This could cause pregnancy. Discuss with your doctor or pharmacist if you should use additional reliable birth control methods while using this medication.

Also tell your doctor if you have any new spotting or breakthrough bleeding, because these may be signs that your birth control is not working well. This medication may interfere with certain medical/laboratory tests, possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug. Surprising Reasons You're in Pain Slideshow Take the Pain Quiz Joint-Friendly Exercises to Reduce RA Pain Slideshow OVERDOSE: If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Symptoms of overdose may include: severe drowsiness, slow breathing, severe dizziness, persistent nausea/vomiting, unusual sweating. NOTES: Do not share this medication with others. Massage, hot baths, and other relaxation methods can help with tension headaches.

Consult your doctor or pharmacist for more details. Laboratory and/or medical tests (such as liver and kidney function tests) may be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details. MISSED DOSE: Not applicable. STORAGE: Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so.

Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company. Information last revised March 2013. Copyright (c) 2013 First Databank, Inc. Quick Guide Chronic Pain Syndrome: Treatment and Management for CPSMultimedia: Slideshows, Images & Quizzes Headaches Quiz: Learn About Headache Pain If you're plagued with headaches, our Headaches Quiz may help you identify causes, triggers, symptoms, and treatments for... Related Disease Conditions Tension Headache (Symptoms, Relief, Causes, Treatment)A tension headache s one of the most common types of headaches, and the exact cause is not known.

Factors that may contribute to... Treatment & Diagnosis Symptoms & Signs FAQs & Doctor's Views Doctor: Checklist to Take To Your Doctor's Appointment Medications & Supplements Medications Barbiturates Acetaminophen vs. Ibuprofen for Pain (Differences in Side Effects and Dosage)Prevention & Wellness Health Features Drug Name Confusion: Preventing Medication Errors Surprising Reasons You're in Pain Slideshow Take the Pain Quiz Joint-Friendly Exercises to Reduce RA Pain Slideshow Daily Health News The 'Dirty Dozen' of Produce List PCOS and Mental Health Downside of Sugar-Craving Gene First Auto-Darken Contact Lenses Brain Injuries May Cause Dementia More Health News »Trending on Medicine Net Autism Spectrum Disorder (ASD)E. Coli Hepatitis ABurning Urination (Dysuria)Scabies From Pain Management Resources Personalized Tips for Managing Migraine Pain Relief from Head to Toe Exercises for Stronger Knees Featured Centers How Could You Live Better With Migraine?

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Report Problems to the Food and Drug Administration You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA Med Watch website or call 1-800-FDA-1088. See more info: butalbital/acetaminophen/caffeine-oral on Rx List Selected from data included with permission and copyrighted by First Databank, Inc.

This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of particular drug is safe, appropriate or effective for you or anyone else.

A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

References Related Article Pain Management: Surprising Causes of Pain What’s causing your pain? Learn the common causes of lower back pain, as well as pain in the knee, stomach, kidney, shoulder, chest, gallbladder, heel, sciatic nerve, neck, hip, foot and other parts of the body. Find pain management tips that work to help lower pain triggers, as well as other pain treatments. Read more: Pain Management: Surprising Causes of Pain Complete List Top butalbital/acetaminophen/caffeine-oral Related Articles Acetaminophen vs Ibuprofen Side Effects Acetaminophen (Tylenol and many other brand names is an pain reliever (analgesic) and fever reducer (antipyretic ).

Scientists do not know the exact mechanism of action of acetaminophen. Ibuprofen (Advil) is an NSAID (nonsteroidal inti-inflammatory drug) used for the treat inflammation, fever, and mild pain.

Ibuprofen works in relieving mild pain, inflammation, and fever by blocking an enzyme that makes chemicals released in the body that promote inflammation (prostaglandins). Prostaglandins promote inflammation in the body. Common side effects of both acetaminophen and ibuprofen include rash, nausea, and headache. Side effects specific to acetaminophen include kidney damage, anemia, thrombocytopenia, serious skin reactions, and liver failure. Side effects of specific to ibuprofen include tinnitus (ringing in the ears), dizziness, drowsiness, stomach pain, constipation, and heartburn. Dosage depends upon whether the person using acetaminophen or ibuprofen.barbiturates-oral Barbiturates are a class of drugs prescribed to treat headaches, insomnia, and seizures. Examples of barbiturates include:belladonna and phenobarbital (Donnatal

), butalbital/acetaminophen/caffeine (Esgic, Fioricet), butalbital/aspirin/caffeine (Fiorinal Ascomp, Fortabs), butabarbital (Butisol), amobarbital (Amytal), pentobarbital (Nembutal), and secobarbital (Seconal). Side effects, drug interactions, dosage, storage, and pregnancy safety should be reviewed prior to taking this medication.

Headaches Quiz If you're plagued with headaches, our Headaches Quiz may help you identify causes, triggers, symptoms, and treatments for headache pain caused by different types of headaches such as migraines, sinus, cluster, tension, or stress. Tension Headache A tension headache s one of the most common types of headaches, and the exact cause is not known. Factors that may contribute to tension or stress headaches are lack of sleep, increased stress (referred to as a stress headache), skipping meals, dehydration, medical diseases or conditions, anxiety, or changes at home, work, or school.

Treatment of tension headaches include prescription and OTC medications, stress management, and treating any underlying illness or condition.

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IONSEsgic® Capsules (butalbital, acetaminophen and caffeine capsules USP 50 mg/325 mg/40 mg) are indicated for the relief of the symptom complex of tension (or muscle contraction) headache. Evidence supporting the efficacy and safety of this combination product in the treatment of multiple recurrent headaches is unavailable.

Fioricet

Drug Description A Visual Guide to Migraine Headaches Slideshow Headache and Migraine Triggers Slideshow Take the Headaches Quiz Find Lowest Prices on (butalbital, acetaminophen and caffeine) Capsules WARNINGHEPATOTOXICITYACETAMINOPHEN HAS BEEN ASSOCIATED WITH CASES OF ACUTE LIVER FAILURE, AT TIMES RESULTING IN LIVER TRANSPLANT AND DEATH.

MOST OF THE CASES OF LIVER INJURY ARE ASSOCIATED WITH THE USE OF ACETAMINOPHEN AT DOSES THAT EXCEED 4000 MILLIGRAMS PER DAY, AND OFTEN INVOLVE MORE THAN ONE ACETAMINOPHEN-CONTAINING PRODUCT. DESCRIPTIONButalbital, acetaminophen and caffeine are supplied in capsule form for oral administration.

Each capsule contains: Butalbital .................... 50 mg Warning: May be habit-forming. Acetaminophen .......... 325 mg Caffeine ...................... 40 mg In addition, each capsule contains the following inactive ingredients: colloidal silicon dioxide, croscarmellose sodium, magnesium stearate, microcrystalline cellulose with capsule shell composed of gelatin (silicon dioxide and sodium lauryl sulfate added as manufacturing aides to the gelatin) and titanium dioxide. Impriting ink composed of n-butyl alcohol, pharmaceutical glaze modified in SD-45, propylene glycol, SDA-3A alcohol, titanium dioxide, D&C Yellow No.

10 Aluminum Lake and FD&C Blue No. 1 Aluminum Lake. Butalbital (5-allyl-5-isobutylbarbituric acid), a slightly bitter, white, odorless, crystalline powder, is a short to intermediate-acting barbiturate.

It has the following structural formula: C 11 H 16 N 2 O 3 MW = 224 .26Acetaminophen (4'-hydroxyacetanilide), a slightly bitter, white, odorless, crystalline powder, is a nonopiate, non-salicylate analgesic and antipyretic. It has the following structural formula: C 8 H 9 NO 2 MW = 151.16Caffeine (1,3,7-trimethylxanthine), a bitter, white powder or white-glistening needles, is a central nervous system stimulant.

It has the following structural formula: C 8 H 10 N 4 O 2 MW = 194 .19Indications & Dosage A Visual Guide to Migraine Headaches Slideshow Headache and Migraine Triggers Slideshow Take the Headaches Quiz INDICAT

Caution in this regard is required because butalbital is habit-forming and potentially abusable. DOSAGE AND ADMINISTRATIONOne or two capsules every four hours. Total daily dosage should not exceed 6 capsules. Extended and repeated use of this product is not recommended because of the potential for physical dependence. HOW SUPPLIEDEsgic® Capsules , containing butalbital 50 mg ( WARNING: May be habit-forming ), acetaminophen 325 mg and caffeine 40 mg, are opaque white, body and cap, and are imprinted with logo on one side and “535- 12” in kelly green ink.

They are supplied in bottles of 100 capsules, NDC 0535-0012-01. Storage Store at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature ].

Dispense in a tight, light-resistant container with a child-resistant closure. Manufactured by: MIKART, INC, Atlanta, GA 30318. For: GILBERT LABORATORIES, Affiliate of Forest Pharmaceuticals, Inc., St. Louis, Missouri 63045. Revised: Oct 2013Side Effects & Drug Interactions A Visual Guide to Migraine Headaches Slideshow Headache and Migraine Triggers Slideshow Take the Headaches Quiz SIDE EFFECTSFrequently Observed The most frequently reported adverse reactions are drowsiness, lightheadedness, dizziness, sedation, shortness of breath, nausea, vomiting, abdominal pain, and intoxicated feeling.

Infrequently Observed All adverse events tabulated below are classified as infrequent. Central Nervous System: headache, shaky feeling, tingling, agitation, fainting, fatigue, heavy eyelids, high energy, hot spells, numbness, sluggishness, seizure. Mental confusion, excitement or depression can also occur due to intolerance, particularly in elderly or debilitated patients, or due to overdosage of butalbital. Autonomic Nervous System: dry mouth , hyperhidrosis. Gastrointestinal: difficulty swallowing, heartburn, flatulence, constipation. Cardiovascular: tachycardia. Musculoskeletal: leg pain, muscle fatigue. Genitourinary: diuresis.

Miscellaneous: pruritus, fever, earache, nasal congestion, tinnitus, euphoria, allergic reactions. Several cases of dermatological reactions, including toxic epidermal necrolysis and erythema multiforme, have been reported. The following adverse drug events may be borne in mind as potential effects of the components of this product.

Potential effects of high dos age are listed in the OVERDOSAGE section. Acetaminophen: allergic reactions, rash, thrombocytopenia, agranulocytosis. Caffeine: cardiac stimulation, irritability, tremor, dependence, nephrotoxicity, hyperglycemia. Drug Abuse And Dependence Abuse And Dependee Butalbital Barbiturates may be habit-forming: Tolerance, psychological dependence, and physical dependence may occur especially following prolonged use of high doses of barbiturates.

The average daily dose for the barbiturate addict is usually about 1500 mg. As tolerance to barbiturates develops, the amount needed to maintain the same level of intoxication increases; tolerance to a fatal dosage, however, does not increase more than two-fold.

As this occurs, the margin between an intoxication dosage and fatal dosage becomes smaller. The lethal dose of a barbiturate is far less if alcohol is also ingested. Major withdrawal symptoms (convulsions and delirium) may occur within 16 hours and last up to 5 days after abrupt cessation of these drugs. Intensity of withdrawal symptoms gradually declines over a period of approximately 15 days. Treatment of barbiturate dependence consists of cautious and gradual withdrawal of the drug.

Barbiturate-dependent patients can be withdrawn by using a number of different withdrawal regimens. One method involves initiating treatment at the patient's regular dosage level and gradually decreasing the daily dosage as tolerated by the patient. DRUG INTERACTIONSThe CNS effects of butalbital may be enhanced by monoamine oxidase (MAO) inhibitors.

Butalbital, acetaminophen and caffeine may enhance the effects of: other narcotic analgesics, alcohol, general anesthetics, tranquilizers such as chlordiazepoxide, sedative -hypnotics, or other CNS depressants, causing increased CNS depression. Drug/Laboratory Test Interactions Acetaminophen may produce false-positive test results for urinary 5-hydroxy-indoleacetic acid.

Warnings & Precautions A Visual Guide to Migraine Headaches Slideshow Headache and Migraine Triggers Slideshow Take the Headaches Quiz WARNINGSButalbital is habit-forming and potentially abusable. Consequently, the extended use of this product is not recommended. Hepatotoxicity Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed 4000 milligrams per day, and often involve more than one acetaminophen-containing product.

The excessive intake of acetaminophen may be intentional to cause self-harm or unintentional as patients attempt to obtain more pain relief or unknowingly take other acetaminophen-containing products. The risk of acute liver failure is higher in individuals with underlying liver disease and in individuals who ingest alcohol while taking acetaminophen. Instruct patients to look for acetaminophen or APAP on package labels and not to use more than one product that contains acetaminophen.

Instruct patients to seek medical attention immediately upon ingestion of more than 4000 milligrams of acetaminophen per day, even if they feel well. Serious Skin Reactions Rarely, acetaminophen may cause serious skin reactions such as acute generalized exanthematous pustulosis (AGEP), Stevens-Johnson Syndrome ( SJS ), and toxic epidermal necrolysis (TEN), which can be fatal.

Patients should be informed about the signs of serious skin reactions, and use of the drug should be discontinued at the first appearance of skin rash or any other sign of hypersensitivity. Hypersensitivity/anaphylaxis There have been post-marketing reports of hypersensitivity and anaphylaxis associated with use of acetaminophen.

Clinical signs included swelling of the face, mouth, and throat, respiratory distress, urticaria , rash, pruritus, and vomiting. There were infrequent reports of life-threatening anaphylaxis requiring emergency medical attention. Instruct patients to discontinue Esgic® Capsules immediately and seek medical care if they experience these symptoms.

Do not prescribe Esgic® Capsules for patients with acetaminophen allergy. PRECAUTIONSGeneral Esgic® Capsules should be prescribed with caution in certain special-risk patients, such as the elderly or debilitated, and those with severe impairment of renal or hepatic function, or acute abdominal conditions.

Laboratory Tests In patients with severe hepatic or renal disease, effects of therapy should be monitored with serial liver and/or renal function tests. Carcinogenesis, Mutagenesis, Impairment Of Fertility No adequate studies have been conducted in animals to determine whether acetaminophen or butalbital have a potential for carcinogenesis, mutagenesis or impairment of fertility.

Pregnancy Teratogenic Effects Pregnancy Category CAnimal reproduction studies have not been conducted with this combination product. It is also not known whether butalbital, acetaminophen and caffeine can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity.

This product should be given to a pregnant woman only when clearly needed. Nonteratogenic Effects Withdrawal seizures were reported in a two-day-old male infant whose mother had taken a butalbitalcontaining drug during the last two months of pregnancy.

Butalbital was found in the infant's serum. The infant was given phenobarbital 5 mg/kg, which was tapered without further seizure or other withdrawal symptoms. Nursing Mothers Caffeine, barbiturates and acetaminophen are excreted in breast milk in small amounts, but the significance of their effects on nursing infants is not known.

Because of potential for serious adverse reactions in nursing infants from butalbital, acetaminophen and caffeine, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Pediatric Use Safety and effectiveness in pediatric patients below the age of 12 have not been established. Geriatric Use Clinical studies of butalbital, acetaminophen and caffeine capsules did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Other reported clinical experience has not identified differences in responses between the elderly and younger patients.

In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.

Butalbital is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function.

Overdosage & Contraindications A Visual Guide to Migraine Headaches Slideshow Headache and Migraine Triggers Slideshow Take the Headaches Quiz OVERDOSEFollowing an acute overdosage of butalbital, acetaminophen and caffeine, toxicity may result from the barbiturate or the acetaminophen.

Toxicity due to caffeine is less likely, due to the relatively small amounts in this formulation. Signs And Symptoms Toxicity from barbiturate poisoning includes drowsiness, confusion, and coma; respiratory depression; hypotension; and hypovolemic shock. In acetaminophen overdosage: dose-dependent, potentially fatal hepatic necrosis is the most serious adverse effect. Renal tubular necroses, hypoglycemic coma and coagulation defects may also occur. Early symptoms following a potentially hepatotoxic overdose may include: nausea, vomiting, diaphoresis and general malaise.

Clinical and laboratory evidence of hepatic toxicity may not be apparent until 48 to 72 hours post-ingestion. Acute caffeine poisoning may cause insomnia, restlessness, tremor, and delirium, tachycardia and extrasystoles. Treatment A single or multiple drug overdose with this combination product is a potentially lethal polydrug overdose, and consultation with a regional poison control center is recommended. Immediate treatment includes support of cardiorespiratory function and measures to reduce drug absorption.

Oxygen, intravenous fluids, vasopressors, and other supportive measures should be employed as indicated. Assisted or controlled ventilation should also be considered. Gastric decontamination with activated charcoal should be administered just prior to N-acetylcysteine (NAC) to decrease systemic absorption if acetaminophen ingestion is known or suspected to have occurred within a few hours of presentation. Serum acetaminophen levels should be obtained immediately if the patient presents 4 hours or more after ingestion to assess potential risk of hepatotoxicity; acetaminophen levels drawn less than 4 hours post-ingestion may be misleading.

To obtain the best possible outcome, NAC should be administered as soon as possible where impending or evolving liver injury is suspected. Intravenous NAC may be administered when circumstances preclude oral administration. Vigorous supportive therapy is required in severe intoxication. Procedures to limit the continuing absorption of the drug must be readily performed since the hepatic injury is dose dependent and occurs early in the course of intoxication.

CONTRAINDICATIONSThis product is contraindicated under the following conditions: Hypersensitivity or intolerance to any component of this product.

Patients with porphyria. Clinical Pharmacology A Visual Guide to Migraine Headaches Slideshow Headache and Migraine Triggers Slideshow Take the Headaches Quiz CLINICAL PHARMACOLOGYThis combination drug product is intended as a treatment for tension headache. It consists of a fixed combination of butalbital, acetaminophen and caffeine. The role each component plays in the relief of the complex of symptoms known as tension headache is incompletely understood.

Pharmacokinetics The behavior of the individual components is described below. Butalbital Butalbital is well absorbed from the gastrointestinal tract and is expected to distribute to most tissues in the body.

Barbiturates in general may appear in breast milk and readily cross the placental barrier. They are bound to plasma and tissue proteins to a varying degree and binding increases directly as a function of lipid solubility.

Elimination of butalbital is primarily via the kidney (59% to 88% of the dose) as unchanged drug or metabolites. The plasma half-life is about 35 hours. Urinary excretion products include parent drug (about 3.6% of the dose), 5-isobutyl-5- (2,3-dihydroxypropyl) barbituric acid (about 24% of the dose), 5-allyl-5 (3-hydroxy-2-methyl-1-propyl) barbituric acid (about 4.8% of the dose), products with the barbituric acid ring hydrolyzed with excretion of urea (about 14% of the dose), as well as unidentified materials.

Of the material excreted in the urine, 32% is conjugated. The in vitro plasma protein binding of butalbital is 45% over the concentration range of 0.5 to 20 mcg/m L. This falls within the range of plasma protein binding (20% to 45%) reported with other barbiturates such as phenobarbital, pentobarbital, and secobarbital sodium.

The plasma-to-blood concentration ratio was almost unity, indicating that there is no preferential distribution of butalbital into either plasma or blood cells (See OVERDOSAGE for toxicity information ). Acetaminophen Acetaminophen is rapidly absorbed from the gastrointestinal tract and is distributed throughout most body tissues. The plasma half-life is 1.25 to 3 hours, but may be increased by liver damage and following overdosage.

Elimination of acetaminophen is principally by liver metabolism (conjugation) and subsequent renal excretion of metabolites. Approximately 85% of an oral dose appears in the urine within 24 hours of administration, most as the glucuronide conjugate, with small amounts of other conjugates and unchanged drug. (See OVERDOSAGE for toxicity information ). Caffeine Like most xanthines, caffeine is rapidly absorbed and distributed in all body tissues and fluids, including the CNS, fetal tissues, and breast milk. Caffeine is cleared through metabolism and excretion in the urine. The plasma half-life is about 3 hours.

Hepatic biotransformation prior to excretion, results in about equal amounts of 1-methylxanthine and 1-methyluric acid. Of the 70% of the dose that is recovered in the urine, only 3% is unchanged drug. (See OVERDOSAGE for toxicity information ). Medication Guide A Visual Guide to Migraine Headaches Slideshow Headache and Migraine Triggers Slideshow Take the Headaches Quiz PATIENT INFORMATIONInformation For Patients /Caregivers Do not take Esgic® Capsules if you are allergic to any of its ingredients.

If you develop signs of allergy such as a rash or difficulty breathing, stop taking Esgic® Capsules and contact your healthcare provider immediately. Do not take more than 4000 milligrams of acetaminophen per day. Call your doctor if you took more than the recommended dose. This product may impair mental and/or physical abilities required for the performance of potentially hazardous tasks such as driving a car or operating machinery.

Such tasks should be avoided while taking this product. Alcohol and other CNS depressants may produce an additive CNS depression, when taken with this combination product, and should be avoided. Butalbital may be habit-forming. Patients should take the drug only for as long as it is prescribed, in the amounts prescribed, and no more frequently than prescribed.

Report Problems to the Food and Drug Administration You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA Med Watch website or call 1-800-FDA-1088. From Migraines and Headaches Resources Preventive Therapy for Migraine Personalized Tips for Managing Migraine A Visual Guide to Migraines Featured Centers How Could You Live Better With Migraine? Not Being Defined by Your Cancer Track Cold & Flu in Your Area Health Solutions From Our Sponsors Frequent Constipation? Greater Food Accessibility

IONSEsgic® Capsules (butalbital, acetaminophen and caffeine capsules USP 50 mg/325 mg/40 mg) are indicated for the relief of the symptom complex of tension (or muscle contraction) headache. Evidence supporting the efficacy and safety of this combination product in the treatment of multiple recurrent headaches is unavailable.

Fioricet

Drug Description A Visual Guide to Migraine Headaches Slideshow Headache and Migraine Triggers Slideshow Take the Headaches Quiz Find Lowest Prices on (butalbital, acetaminophen and caffeine) Capsules WARNINGHEPATOTOXICITYACETAMINOPHEN HAS BEEN ASSOCIATED WITH CASES OF ACUTE LIVER FAILURE, AT TIMES RESULTING IN LIVER TRANSPLANT AND DEATH.

MOST OF THE CASES OF LIVER INJURY ARE ASSOCIATED WITH THE USE OF ACETAMINOPHEN AT DOSES THAT EXCEED 4000 MILLIGRAMS PER DAY, AND OFTEN INVOLVE MORE THAN ONE ACETAMINOPHEN-CONTAINING PRODUCT. DESCRIPTIONButalbital, acetaminophen and caffeine are supplied in capsule form for oral administration.

10 Aluminum Lake and FD&C Blue No. 1 Aluminum Lake. Butalbital (5-allyl-5-isobutylbarbituric acid), a slightly bitter, white, odorless, crystalline powder, is a short to intermediate-acting barbiturate.

It has the following structural formula: C 11 H 16 N 2 O 3 MW = 224 .26Acetaminophen (4'-hydroxyacetanilide), a slightly bitter, white, odorless, crystalline powder, is a nonopiate, non-salicylate analgesic and antipyretic. It has the following structural formula: C 8 H 9 NO 2 MW = 151.16Caffeine (1,3,7-trimethylxanthine), a bitter, white powder or white-glistening needles, is a central nervous system stimulant.

It has the following structural formula: C 8 H 10 N 4 O 2 MW = 194 .19Indications & Dosage A Visual Guide to Migraine Headaches Slideshow Headache and Migraine Triggers Slideshow Take the Headaches Quiz INDICAT

Caution in this regard is required because butalbital is habit-forming and potentially abusable. DOSAGE AND ADMINISTRATIONOne or two capsules every four hours. Total daily dosage should not exceed 6 capsules. Extended and repeated use of this product is not recommended because of the potential for physical dependence. HOW SUPPLIEDEsgic® Capsules , containing butalbital 50 mg ( WARNING: May be habit-forming ), acetaminophen 325 mg and caffeine 40 mg, are opaque white, body and cap, and are imprinted with logo on one side and “535- 12” in kelly green ink.

They are supplied in bottles of 100 capsules, NDC 0535-0012-01. Storage Store at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature ].

Dispense in a tight, light-resistant container with a child-resistant closure. Manufactured by: MIKART, INC, Atlanta, GA 30318. For: GILBERT LABORATORIES, Affiliate of Forest Pharmaceuticals, Inc., St. Louis, Missouri 63045. Revised: Oct 2013Side Effects & Drug Interactions A Visual Guide to Migraine Headaches Slideshow Headache and Migraine Triggers Slideshow Take the Headaches Quiz SIDE EFFECTSFrequently Observed The most frequently reported adverse reactions are drowsiness, lightheadedness, dizziness, sedation, shortness of breath, nausea, vomiting, abdominal pain, and intoxicated feeling.

Miscellaneous: pruritus, fever, earache, nasal congestion, tinnitus, euphoria, allergic reactions. Several cases of dermatological reactions, including toxic epidermal necrolysis and erythema multiforme, have been reported. The following adverse drug events may be borne in mind as potential effects of the components of this product.

Potential effects of high dos age are listed in the OVERDOSAGE section. Acetaminophen: allergic reactions, rash, thrombocytopenia, agranulocytosis. Caffeine: cardiac stimulation, irritability, tremor, dependence, nephrotoxicity, hyperglycemia. Drug Abuse And Dependence Abuse And Dependee Butalbital Barbiturates may be habit-forming: Tolerance, psychological dependence, and physical dependence may occur especially following prolonged use of high doses of barbiturates.

The average daily dose for the barbiturate addict is usually about 1500 mg. As tolerance to barbiturates develops, the amount needed to maintain the same level of intoxication increases; tolerance to a fatal dosage, however, does not increase more than two-fold.

As this occurs, the margin between an intoxication dosage and fatal dosage becomes smaller. The lethal dose of a barbiturate is far less if alcohol is also ingested. Major withdrawal symptoms (convulsions and delirium) may occur within 16 hours and last up to 5 days after abrupt cessation of these drugs. Intensity of withdrawal symptoms gradually declines over a period of approximately 15 days. Treatment of barbiturate dependence consists of cautious and gradual withdrawal of the drug.

Barbiturate-dependent patients can be withdrawn by using a number of different withdrawal regimens. One method involves initiating treatment at the patient's regular dosage level and gradually decreasing the daily dosage as tolerated by the patient. DRUG INTERACTIONSThe CNS effects of butalbital may be enhanced by monoamine oxidase (MAO) inhibitors.

Butalbital, acetaminophen and caffeine may enhance the effects of: other narcotic analgesics, alcohol, general anesthetics, tranquilizers such as chlordiazepoxide, sedative -hypnotics, or other CNS depressants, causing increased CNS depression. Drug/Laboratory Test Interactions Acetaminophen may produce false-positive test results for urinary 5-hydroxy-indoleacetic acid.

Warnings & Precautions A Visual Guide to Migraine Headaches Slideshow Headache and Migraine Triggers Slideshow Take the Headaches Quiz WARNINGSButalbital is habit-forming and potentially abusable. Consequently, the extended use of this product is not recommended. Hepatotoxicity Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed 4000 milligrams per day, and often involve more than one acetaminophen-containing product.

The excessive intake of acetaminophen may be intentional to cause self-harm or unintentional as patients attempt to obtain more pain relief or unknowingly take other acetaminophen-containing products. The risk of acute liver failure is higher in individuals with underlying liver disease and in individuals who ingest alcohol while taking acetaminophen. Instruct patients to look for acetaminophen or APAP on package labels and not to use more than one product that contains acetaminophen.

Instruct patients to seek medical attention immediately upon ingestion of more than 4000 milligrams of acetaminophen per day, even if they feel well. Serious Skin Reactions Rarely, acetaminophen may cause serious skin reactions such as acute generalized exanthematous pustulosis (AGEP), Stevens-Johnson Syndrome ( SJS ), and toxic epidermal necrolysis (TEN), which can be fatal.

Patients should be informed about the signs of serious skin reactions, and use of the drug should be discontinued at the first appearance of skin rash or any other sign of hypersensitivity. Hypersensitivity/anaphylaxis There have been post-marketing reports of hypersensitivity and anaphylaxis associated with use of acetaminophen.

Clinical signs included swelling of the face, mouth, and throat, respiratory distress, urticaria , rash, pruritus, and vomiting. There were infrequent reports of life-threatening anaphylaxis requiring emergency medical attention. Instruct patients to discontinue Esgic® Capsules immediately and seek medical care if they experience these symptoms.

Do not prescribe Esgic® Capsules for patients with acetaminophen allergy. PRECAUTIONSGeneral Esgic® Capsules should be prescribed with caution in certain special-risk patients, such as the elderly or debilitated, and those with severe impairment of renal or hepatic function, or acute abdominal conditions.

Laboratory Tests In patients with severe hepatic or renal disease, effects of therapy should be monitored with serial liver and/or renal function tests. Carcinogenesis, Mutagenesis, Impairment Of Fertility No adequate studies have been conducted in animals to determine whether acetaminophen or butalbital have a potential for carcinogenesis, mutagenesis or impairment of fertility.

Pregnancy Teratogenic Effects Pregnancy Category CAnimal reproduction studies have not been conducted with this combination product. It is also not known whether butalbital, acetaminophen and caffeine can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity.

This product should be given to a pregnant woman only when clearly needed. Nonteratogenic Effects Withdrawal seizures were reported in a two-day-old male infant whose mother had taken a butalbitalcontaining drug during the last two months of pregnancy.

Butalbital was found in the infant's serum. The infant was given phenobarbital 5 mg/kg, which was tapered without further seizure or other withdrawal symptoms. Nursing Mothers Caffeine, barbiturates and acetaminophen are excreted in breast milk in small amounts, but the significance of their effects on nursing infants is not known.

In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.

Butalbital is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function.

Overdosage & Contraindications A Visual Guide to Migraine Headaches Slideshow Headache and Migraine Triggers Slideshow Take the Headaches Quiz OVERDOSEFollowing an acute overdosage of butalbital, acetaminophen and caffeine, toxicity may result from the barbiturate or the acetaminophen.

Toxicity due to caffeine is less likely, due to the relatively small amounts in this formulation. Signs And Symptoms Toxicity from barbiturate poisoning includes drowsiness, confusion, and coma; respiratory depression; hypotension; and hypovolemic shock. In acetaminophen overdosage: dose-dependent, potentially fatal hepatic necrosis is the most serious adverse effect. Renal tubular necroses, hypoglycemic coma and coagulation defects may also occur. Early symptoms following a potentially hepatotoxic overdose may include: nausea, vomiting, diaphoresis and general malaise.

Clinical and laboratory evidence of hepatic toxicity may not be apparent until 48 to 72 hours post-ingestion. Acute caffeine poisoning may cause insomnia, restlessness, tremor, and delirium, tachycardia and extrasystoles. Treatment A single or multiple drug overdose with this combination product is a potentially lethal polydrug overdose, and consultation with a regional poison control center is recommended. Immediate treatment includes support of cardiorespiratory function and measures to reduce drug absorption.

To obtain the best possible outcome, NAC should be administered as soon as possible where impending or evolving liver injury is suspected. Intravenous NAC may be administered when circumstances preclude oral administration. Vigorous supportive therapy is required in severe intoxication. Procedures to limit the continuing absorption of the drug must be readily performed since the hepatic injury is dose dependent and occurs early in the course of intoxication.

CONTRAINDICATIONSThis product is contraindicated under the following conditions: Hypersensitivity or intolerance to any component of this product.

Patients with porphyria. Clinical Pharmacology A Visual Guide to Migraine Headaches Slideshow Headache and Migraine Triggers Slideshow Take the Headaches Quiz CLINICAL PHARMACOLOGYThis combination drug product is intended as a treatment for tension headache. It consists of a fixed combination of butalbital, acetaminophen and caffeine. The role each component plays in the relief of the complex of symptoms known as tension headache is incompletely understood.

Pharmacokinetics The behavior of the individual components is described below. Butalbital Butalbital is well absorbed from the gastrointestinal tract and is expected to distribute to most tissues in the body.

Barbiturates in general may appear in breast milk and readily cross the placental barrier. They are bound to plasma and tissue proteins to a varying degree and binding increases directly as a function of lipid solubility.

Elimination of butalbital is primarily via the kidney (59% to 88% of the dose) as unchanged drug or metabolites. The plasma half-life is about 35 hours. Urinary excretion products include parent drug (about 3.6% of the dose), 5-isobutyl-5- (2,3-dihydroxypropyl) barbituric acid (about 24% of the dose), 5-allyl-5 (3-hydroxy-2-methyl-1-propyl) barbituric acid (about 4.8% of the dose), products with the barbituric acid ring hydrolyzed with excretion of urea (about 14% of the dose), as well as unidentified materials.

Of the material excreted in the urine, 32% is conjugated. The in vitro plasma protein binding of butalbital is 45% over the concentration range of 0.5 to 20 mcg/m L. This falls within the range of plasma protein binding (20% to 45%) reported with other barbiturates such as phenobarbital, pentobarbital, and secobarbital sodium.

The plasma-to-blood concentration ratio was almost unity, indicating that there is no preferential distribution of butalbital into either plasma or blood cells (See OVERDOSAGE for toxicity information ). Acetaminophen Acetaminophen is rapidly absorbed from the gastrointestinal tract and is distributed throughout most body tissues. The plasma half-life is 1.25 to 3 hours, but may be increased by liver damage and following overdosage.

Hepatic biotransformation prior to excretion, results in about equal amounts of 1-methylxanthine and 1-methyluric acid. Of the 70% of the dose that is recovered in the urine, only 3% is unchanged drug. (See OVERDOSAGE for toxicity information ). Medication Guide A Visual Guide to Migraine Headaches Slideshow Headache and Migraine Triggers Slideshow Take the Headaches Quiz PATIENT INFORMATIONInformation For Patients /Caregivers Do not take Esgic® Capsules if you are allergic to any of its ingredients.

If you develop signs of allergy such as a rash or difficulty breathing, stop taking Esgic® Capsules and contact your healthcare provider immediately. Do not take more than 4000 milligrams of acetaminophen per day. Call your doctor if you took more than the recommended dose. This product may impair mental and/or physical abilities required for the performance of potentially hazardous tasks such as driving a car or operating machinery.

Such tasks should be avoided while taking this product. Alcohol and other CNS depressants may produce an additive CNS depression, when taken with this combination product, and should be avoided. Butalbital may be habit-forming. Patients should take the drug only for as long as it is prescribed, in the amounts prescribed, and no more frequently than prescribed.

Report Problems to the Food and Drug Administration You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA Med Watch website or call 1-800-FDA-1088. From Migraines and Headaches Resources Preventive Therapy for Migraine Personalized Tips for Managing Migraine A Visual Guide to Migraines Featured Centers How Could You Live Better With Migraine? Not Being Defined by Your Cancer Track Cold & Flu in Your Area Health Solutions From Our Sponsors Frequent Constipation? Greater Food Accessibility

Butalbital withdrawal symptoms may be a sign of dependency or addiction to certain medications that combine butalbital with acetaminophen or aspirin and caffeine to treat chronic pain and migraine headaches. These drugs are FDA approved and often prescribed by physicians, but the active ingredients are highly addictive.

Butalbital Withdrawal Symptoms and Signs, and Detoxification

Butalbital Withdrawal Symptoms and Signs, and Detoxification Article Summary Withdrawing from Butalbital: Treatment Methods and Options for Help Gradual Detox Inpatient/Residential Detox Rapid Drug Detox Detoxing, Addiction Treatment Rehab and Recovery Questions and Answers (FAQ)View Resources

Butalbital specifically is a physically and psychologically addictive barbiturate. When used for short-term treatment of pain, withdrawal symptoms are often minor and short-lived. However, barbiturates can be habit-forming and with long-term use, patients may build a tolerance to the drug as well as a psychological and physical dependence.

This means that more of the drug is needed to have the same effect. As use continues, the withdrawal symptoms become more severe. Stopping the use of butalbital-containing medications abruptly can result in a variety of withdrawal symptoms that can occur within eight to 36 hours of the last dose of medication and last up to seven days.

These symptoms can include elevated body temperature and blood pressure, increased heart and respiratory rates, delirium, vomiting, tremors, ringing in the ears, breathing difficulties, drowsiness, raised consciousness, nervousness, disorientation and severe headaches. Although rare, more serious withdrawal symptoms and signs include abnormal vital signs and seizures.

Butalbital withdrawal symptoms and signs typically decrease in intensity over a period of about two weeks, but treatment is often necessary during detoxification to manage symptoms and to prevent medical complications. Withdrawing from Butalbital: Treatment Methods and Options for Help Withdrawing from butalbital is a necessary part of the detoxification process. Symptoms can be intense because many detoxification treatment methods require that the patient stops use of butalibital drugs completely to rid the body of its effects as rapidly as possible.

Successful detoxification is vital to long-term recovery from butalbital addiction and is best achieved in a medically supervised environment. There are several treatment options available for withdrawing from butalbital, but these can be narrowed down to three basic methods.

Gradual Detox In some programs, the withdrawal and detoxification process is careful and gradual. For example, the patient is given the regular dosage of the drug for a short period and then this dosage is decreased daily to minimize the withdrawal symptoms.

Withdrawal symptoms can be treated in an outpatient setting with the use of benzodiazepines or phenobarbital, but regular medical supervision by your physician or a treatment facility is necessary. Pathfinders Recovery Center Lakewood , Colorado 80228North Point Recovery Boise , Idaho 83713Alpine Recovery Lodge Alpine , Utah 84004Desert Cove Recovery Scottsdale , Arizona 85260Inpatient/Residential Detox Inpatient or residential detoxification methods involve butalbital withdrawal treatment through rapid detoxification, where the patient stays in a medical facility and stops all doses of butalbital completely.

This method is supervised by a medical professional and the patient is given care and medication to treat withdrawal symptoms until detoxification is complete. This method of butalbital withdrawal treatment is not recommended for outpatient treatment, because severe withdrawal symptoms such as seizures or abnormal vital signs should be monitored and aggressively treated by a medical professional to ensure the patient's safety and overall good health.

Rapid Drug Detox Rapid drug detox treatment methods may also utilize a medical procedure in which the patient detoxes under anesthesia, which eliminates most withdrawal symptoms. The patient is given medication that enables them to relax and then is put under a general anesthesia for about an hour.

When the procedure is completed, recovery is carried out under close medical supervision. This procedure is available only on an inpatient treatment basis and can be an ideal long-term recovery method.

Detoxing, Addiction Treatment Rehab and Recovery Detoxification is the first stage in treating butalbital addiction and typically lasts from seven days to a few weeks. This duration depends on the level of addiction and the patient's method of treatment. As with many addiction treatment programs, rehab and recovery is recommended after detoxing.

Rehab and recovery can be carried out in a variety of settings, such as a medical outpatient clinic with counseling services and group support or in a private or public-funded inpatient rehab facility.

The benefit of an inpatient facility is that the patient receives around-the-clock care and support to ensure a successful recovery from butalbital addiction. This treatment option depends largely on the patient's situation and whether other commitments, such as a job, allow for inpatient care.

The critical first step in recovery is butalbital detoxification and treatment of withdrawal symptoms. If you or someone you know is battling butalbital withdrawal symptoms, or showing signs of addiction, call 1-888-935-1318Who Answers?

to contact a medical professional immediately and discover what your options are for treatment. Calls are private and there is no obligation or cost for information. Butalbital Information at a Glance Medication Name, Costs Class of Medicine Generic Name: Variable- Butalbital is used as a combination drug for pain relief Generic Name Variations: Variable Chemical Name: Butalbital Brand Name: Varies Brand Name Variations: Varies Cost/Price: Varies Used to Treat Addiction?

No Function or Use at Low Dose: Varies Function or Use at High Dose: Varies Chemical Makeup: C 11 H 16 N 2 O 3System: barbiturate Duration of Action: Varies Form, Intake, and Dosage Interactions and Complications Drug Forms: Concentrated form or powder Administration Routes: tablet taken orally Dosage: Varies Overdose: Varies Alcohol Interaction: Increased intoxication Illicit Drugs: Increases effects of opiates Prescription Medications: Increases effect of opiate based prescriptions Contraindications: Varies Effects and Adverse Reactions Substance Abuse Short-Term: Dizziness, drowsiness, intoxicated feeling, sedation, euphoria, constipation Long-Term: Addiction, Steven-Johnson’s syndrome, tolerance Risk of Substance Abuse: Moderate Signs of Abuse: Depression, body tremors, memory loss, severe mood swings Physiological Problem Signs and Symptoms Dependence and Addiction Issues Withdrawal Syndrome Onset: 4-72 hours after last dose Withdrawal Symptoms: Depression, body tremors, rage or anxiety Tolerance: Tolerance is easily built to butalbital after extended use Cross Dependence: Varies Physical Dependence: High Psychological Dependence: High Legal Schedules and Ratings Controlled Substances Act Rating: Schedule III Controlled Substance Questions and Answers (FAQ)How Long Do Butalbital Withdrawals Last?

While the duration of detox only lasts about 72 hours, the timeline of withdrawal from a system varies between different individuals.

The length of withdrawal symptoms may last anywhere from a few weeks to several months. Do You Have a List Popular Slang or Street Names for Butalbital? Butalbital is found in other drugs as an ingredient. What are Common Misspellings? Butalbital withdrawl, Butalbital withdrawls, Butalbital withdrawal, Butalbital withdrawels, butabital withdrawal, butalbeetal, butalbutil Are There any Home Remedies for Getting Clean Safely?

Butalbital is incredibly dangerous and difficult to detox from. There are some claims that drinking teas or water will act as a natural detoxifier and rid your body of the butalbital; unfortunately, this will not help to ease the effects of withdrawal. When trying to stop using butalbital based prescriptions it is important that you not use a home remedy or alternative methods to detox.

You will be able to find the most relief by and success by using a professional treatment center. They have been trained to ease and relieve people who are dealing with withdrawal symptoms.

You can find one in your area by calling 1-888-935-1318 Who Answers? or visiting our locator page. How Long Does it Take to Detox from Butalbital? The physical detox process may take between 24 and 72 hours.

Because of the complicated nature of detoxification, there are many options and programs you can use to aid you in becoming and staying clean. Each system will have its own method, it is best to choose the one that you feel suits you best. Review the options near you by looking up local recovery centers or by calling 1-888-935-1318 Who Answers?. Recovery and freedom can start with a simple phone call. View Resources Wikipedia: Controlled Substances Act Wikipedia: Info about butalbital Click here to see the prescription drug abuse chart Read more about fiorinal with codeine: concise monograph

Butalbital-containing medications, like Fiorinal (butalbital/aspirin/caffeine) and Fioricet (butalbital/acetaminophen/caffeine), are commonly over-utilized in the treatment of headaches. Let's explore the use of butalbital-containing medications for your headaches, and how a person can safely withdraw from them under a doctor's care.

Butalbital for Headaches and Dependency Risk

Brain & Nervous System Headaches & Migraines Treatment Butalbital for Headaches and Dependency Risk Rebound Headache and Withdrawal From Butalbital-Containing Medications By Teri Robert Updated February 22, 2018Share Pin Email Print JGI/Jamie Grill/Getty Images

What Is Butalbital? Butalbital is a short-acting barbiturate, often used in combination with Tylenol (acetaminophen), aspirin, and/or caffeine to treat headaches. As a barbiturate, it depresses or slows down the central nervous system, causing a number of effects, depending on the dose.

At lower doses, it relaxes muscles, providing headache relief for some. At higher doses, barbiturates are used as sedatives and even for anesthesia. Why Is Butalbital Not an Ideal Headache Medication? A person who takes butalbital for their headaches is at risk of developing chronic headaches and/or medication overuse headache, also known as a rebound headache. With a rebound headache, a person feels an increase in their head pain intensity after abruptly stopping their medication. This increased pain makes it extra difficult to discontinue the medication, which perpetuates the headache cycle.

Taking medications as few as two to three times a week can lead to a rebound headache. According to scientists, it's more the frequency than the actual dose that is a bigger risk factor for developing a rebound headache. Breaking the Cycle of a Butalbital Rebound Headache When a person stops butalbital, they are at risk for withdrawal symptoms, especially if they are taking frequent and/or high amounts.

In this case, a gradual taper off butalbital is necessary to prevent seizures — a potential withdrawal symptom. Phenobarbital, a long-acting barbiturate, can help patients withdraw from large amounts of butalbital-containing medications. The administration of phenobarbital is done gradually, in a tapered fashion. This means that the dose is slowly decreased every couple days and is done in a monitored setting under the care of a physician.

On average, the withdrawal process can take 3 weeks. This is not a hard and fast rule though and may be longer or shorter based on the dose and frequency of butalbital the person had been taking.

It also depends on the presence of distressing withdrawal symptoms while in the hospital. What Does This Mean for Me?

If you are concerned about your use of butalbital, please speak with your doctor before altering the dose or frequency on your own. It's also imperative you speak with your doctor during the withdrawal process about safer strategies to treat your headaches in the future.

Your doctor may recommend a preventive headache medication or alternative therapies, like biofeedback or meditation, to supplement your headache medications. Sources: American Headache Society. (2015). Too Many Migraine Patients Are Getting Opioids and Barbiturates for Their Pain. American Headache Society. (2008). Chronic Daily Headache and Chronic Migraine. Loder E & Biondi D. Oral phenobarbital loading: a safe and effective method of withdrawing patients withheadachefrom butalbital compounds. Headache. 2003 Sep;43 (8):904-9.

oralbutalbital-aspirin-caffeine oral brand names and other generic formulations include: Butalbital Compound Oral, Farbital Oral, Fembutal Oral, Fiorgen Oral, Fiorinal Oral, Fiormor Oral, Fiortal Oral, Fortabs Oral, Idenal Oral, Isolin Oral, Isollyl Oral, Lanorinal Oral, Tenstan Oral, Vibutal Oral

Drug interactions with butalbital-aspirin-caffeine oral and phenobarbital oral

Drug interactions with butalbital-aspirin-caffeine oral and phenobarbital

All generic drug interactions for butalbital-aspirin-caffeine oral (lists will include brand and generic names):3 contraindicated drug interactions74 serious drug interactions694 significant drug interactions206 minor drug interactionsphenobarbital oral brand names and other generic formulations include: Barbita Oral, Neuroval Oral, Sk-Phenobarbital Oral, Solfoton Oral All generic drug interactions for phenobarbital oral (lists will include brand and generic names):14 contraindicated drug interactions75 serious drug interactions591 significant drug interactions170 minor drug interactions Patients and Caregivers Clinician Explanation Monitor Closely Potential for interactionbutalbital-aspirin-caffeine oral and phenobarbital oralbutalbital-aspirin-caffeine oral and phenobarbital oral both increase sedation and drowsiness.

Patient Drug Interactions Source: Rx List© 2018 Rx List, Inc. Patients and Caregivers Clinician Explanation Monitor Closely Potential for interactionphenobarbital oral and butalbital-aspirin-caffeine oralphenobarbital oral increases and butalbital-aspirin-caffeine oral decreases sedation and drowsiness.

Patient Drug Interactions Source: Rx List© 2018 Rx List, Inc. Check for more interactions with the Drug Interaction Checker Check Now »Drug Interaction Categories Contraindicated Never use this combination of drugs because of high risk for dangerous interaction Serious Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed Significant Potential for significant interaction (monitoring by your doctor is likely required)Minor Interaction is unlikely, minor, or nonsignificant Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider.

The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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That could be a migraine headache or a muscle tension headache. If it happens often you should discuss it with your doctor. You could try an over the counter migraine remedy to see if it provides relief. They contain a combination of aspirin, acetaminophen and caffeine.

What causes shooting sharp pain in right side of head?

"Answers.com ® Wiki Answers ® Categories Health Conditions and Diseases Head, Ears, and Nose Headaches What causes shooting sharp pain in right side of head? Flag What causes shooting sharp pain in right side of head? Edit Answer by cat kluss Confidence votes 55.7K

Resting your head on a cold pack might help and on the other hand a warm shower can help. Sometimes a strong cup of coffee can help.4 people found this useful Was this answer useful? Yes Somewhat No Scythe17 419 Contributions What causes sharp shooting pains in your head and is it serious? Idiopathic stabbing headache was first described in 1964, at which time it was called ""ophthalmodynia periodica"" (Lansche 1964).

Since then, brief, sharp, jabbing pains that o …Sensirie 1,362 Contributions What causes sharp shooting pains in your head?

A number of reasons: being in contact with direct/bright light such as the sun, a toothache, migraine, prolonged starvation and lack of caffeine (for those who consume high ca …What causes a sharp shooting pain in the right side of the head and only happens every few minutes? The International Headache Society describes a type of headache called ""primary stabbing headache"".

They are also called ice pick headaches. Edit What causes sharp shooting pains in your side? gas gas gas Edit What could be cause of sharp shooting pain in right testicle? could be an infection in sperm sac Edit What causes a sharp shooting pain in the left side of the head and only happens for a few seconds?

I have heard, If you dont have enough fiber or sodium in your diet that head painse could happen. Edit What causes a sharp shooting pain in the head?

You have a headache if you have shooting pain in your head. Headaches can be caused by lack of sleep, lack of caffeine if it is a staple in your diet, head injury, or high …Lu121976 319 Contributions What would cause me to have a Sharp shooting pain through your head from one side to the other and it only lasts a couple of seconds?stress Edit Callummdh 502 Contributions I have a sharp pain on the right side of my head what could it be?

Most likely a headache, nothing to worry about. If it continues to hurt, visit your GP/doctor Edit Rachel Carmine 10 Contributions What causes sharp pain in the right back side of my head? A headache or could be a nerve problem depending on what makes it hurt. if it to light that makes it hurt then i could be a nerve that's being compressed.

if its touch then …Peaceout333 2,299 Contributions What is a sharp pain in the right side of your head? a headache Edit What causes a sharp shooting pain in the back of the head? Have you researched Occipital Neuralgia.

I have it and know other who do and we have those symptoms. I suggest you ""image"" google Occipital neuralgia and I think it may …Answered In Health How do you get rid of sharp pain in right side of head? A sharp shooting pain means you have only a few muscles pinched or tight in your neck so the pain is much more concentrated than if you had a bunch of them pinched.

You ca …Mz.kiera 9 Contributions Answered In Conditions and Diseases What could be causing a sharp pain on my right side and it shoots to my back all test came out negative?

You could have a baby maybe you are sleeping the wrong way nd the way you are sleeping is cuttin your blood flow off..and when that happens the blood cant go threw nd its caus …Mezlove 428 Contributions Answered In Conditions and Diseases When it gets near the end of the day get sharp shooting pains on the right side of the head shooting from the back to the front and have quite a large lump on the right of the crown any ideas?

It could possibly be a tumor. You shuold get it checked out immediantly. Edit Ellen Schnakenberg 3,058 Contributions Professional Patient Advocate/E-Patient Answered In Headaches What causes shooting pain on right side of head?

Shooting pain on one side of the head can be a symptom of any of a number of different disorders or diseases including occipital neuralgia or ice pick headaches. For a diagnos …Ellen Schnakenberg 3,058 Contributions Professional Patient Advocate/E-Patient Answered In Headaches What causes sharp pains on the the left side of the head? Sharp pains on the side of the head may be symptoms of a type of headache called an ice pick headache, or primary stabbing headache. Only a doctor can diagnose you however, so … "

eacetaminophen/butalbital/caffeine/codeine systemic Brand names: Fioricet with Codeine, Phrenilin with Caffeine and Codeine Drug class (es): narcotic analgesic combinations Acetaminophen/butalbital/caffeine/codeine systemic is used in the treatment of:

Acetaminophen

Acetaminophen Important: The information below refers to medicines available in the United States that contain acetaminophen.

Medications containing acetaminophen:acetaminophen systemic Brand names: Tylenol, Paracetamol, Mapap, Tylenol Arthritis Pain Drug class (es): miscellaneous analgesics Acetaminophen systemic is used in the treatment of: Fever Muscle Pain Neck Pain Pain Plantar Fasciitis Sciatica Transverse Myelitis Multi-ingredient medications containing acetaminophen:acetaminophen/aluminum hydroxide/aspirin/caffeine/magnesium hydroxide systemic Drug class (es): analgesic combinations Acetaminophen/aluminum hydroxide/aspirin/caffeine/magnesium hydroxide systemic is used in the treatment of: Painacetaminophen/aspirin systemic Brand names: Goody's Body Pain, Excedrin Back & Body Drug class (es): analgesic combinations Acetaminophen/aspirin systemic is used in the treatment of: Back Pain Osteoarthritis Pain Rheumatoid Arthritisacetaminophen/aspirin/caffeine systemic Brand names: Excedrin, Excedrin Migraine, Migraine Relief, Vanquish Drug class (es): analgesic combinations Acetaminophen/aspirin/caffeine systemic is used in the treatment of: Migraine Osteoarthritis Pain/Feveracetaminophen/aspirin/caffeine/salicylamide systemic Brand names: Painaid, Saleto, Levacet, Exaprin Drug class (es): analgesic combinations Acetaminophen/aspirin/caffeine/salicylamide systemic is used in the treatment of: Migraine Painacetaminophen/aspirin/codeine systemicacetaminophen/aspirin/diphenhydramine systemic Brand names: Excedrin PM Headache Drug class (es): analgesic combinations Acetaminophen/aspirin/diphenhydramine systemic is used in the treatment of: Headache Insomnia Painacetaminophen/aspirin/phenylpropanolamine systemic Brand names: Rhinocaps Drug class (es): upper respiratory combinationsacetaminophen/benzhydrocodone systemic Brand names: Apadaz Drug class (es): narcotic analgesic combinations Acetaminophen/benzhydrocodone systemic is used in the treatment of: Painacetaminophen/brompheniramine systemic Brand names: Staflex Drug class (es): analgesic combinations Acetaminophen/brompheniramine systemic is used in the treatment of: Allergic Rhinitis Cold Symptoms Pain/Feveracetaminophen/brompheniramine/dextromethorphan/pseudoephedrine systemic Drug class (es): upper respiratory combinations Acetaminophen/brompheniramine/dextromethorphan/pseudoephedrine systemic is used in the treatment of: Allergic Rhinitis Cold Symptomsacetaminophen/brompheniramine/phenylpropanolamine systemic Drug class (es): upper respiratory combinationsacetaminophen/brompheniramine/pseudoephedrine systemic Brand names: Comtrex Acute Head Cold, Dristan Cold Maximum Strength Drug class (es): upper respiratory combinationsacetaminophen/butalbital systemic Brand names: Cephadyn, Bupap, Tencon, Phrenilin Drug class (es): analgesic combinations Acetaminophen/butalbital systemic is used in the treatment of: Headacheacetaminophen/butalbital/caffeine systemic Brand names: Fioricet, Esgic, Capacet, Fiorpap Drug class (es): analgesic combinations Acetaminophen/butalbital/caffeine systemic is used in the treatment of: Headach

Headacheacetaminophen/caffeine systemic Brand names: Headache Relief, Excedrin Tension Headache, Excedrin Mild Headache, Valorin Extra Drug class (es): analgesic combinations Acetaminophen/caffeine systemic is used in the treatment of: Cold Symptoms Headache Osteoarthritis Pain Period Pain Sinusitisacetaminophen/caffeine/chlorpheniramine/hydrocodone/phenylephrine systemic Brand names: Hycomine Compound Drug class (es): upper respiratory combinations Acetaminophen/caffeine/chlorpheniramine/hydrocodone/phenylephrine systemic is used in the treatment of: Cold Symptoms Cough and Nasal Congestionacetaminophen/caffeine/chlorpheniramine/phenylpropanolamine systemic Brand names: Sinapils Drug class (es): upper respiratory combinationsacetaminophen/caffeine/dihydrocodeine systemic Brand names: Trezix, DHC Plus, Panlor SS, Panlor Drug class (es): narcotic analgesic combinations Acetaminophen/caffeine/dihydrocodeine systemic is used in the treatment of: Painacetaminophen/caffeine/guaifenesin/phenylephrine systemic Brand names: Emagrin Forte (old formulation) Drug class (es): upper respiratory combinationsacetaminophen/caffeine/isometheptene mucate systemic Brand names: Prodrin, Migra Ten, Migralam Drug class (es): analgesic combinations Acetaminophen/caffeine/isometheptene mucate systemic is used in the treatment of: Headacheacetaminophen/caffeine/magnesium salicylate systemic Brand names: Knee Relief Drug class (es): analgesic combinations Acetaminophen/caffeine/magnesium salicylate systemic is used in the treatment of: Muscle Painacetaminophen/caffeine/magnesium salicylate/phenyltoloxamine systemic Brand names: Combiflex ES, Durabac Forte, Cafgesic Forte Drug class (es): analgesic combinations Acetaminophen/caffeine/magnesium salicylate/phenyltoloxamine systemic is used in the treatment of: Painacetaminophen/caffeine/phenylpropanolamine/salicylamide systemic Brand names: Saleto-D Drug class (es): upper respiratory combinationsacetaminophen/caffeine/phenyltoloxamine systemic Brand names: Flextra, Flextra Plus Drug class (es): analgesic combinations Acetaminophen/caffeine/phenyltoloxamine systemic is used in the treatment of: Cold Symptoms Headache Pain Sinusitisacetaminophen/caffeine/phenyltoloxamine/salicylamide systemic Brand names: Combiflex, Cafgesic, Durabac Drug class (es): analgesic combinations Acetaminophen/caffeine/phenyltoloxamine/salicylamide systemic is used in the treatment of: Painacetaminophen/caffeine/pyrilamine systemic Brand names: Menstrual Relief, Menstrual Relief Extra Strength, Menstrual Relief Maximum Strength, Midol Complete Drug class (es): analgesic combinations Acetaminophen/caffeine/pyrilamine systemic is used in the treatment of: Premenstrual Dysphoric Disorder Premenstrual Syndromeacetaminophen/caffeine/salicylamide systemic Brand names: Rid-A-Pain Compoundacetaminophen/chlophedianol/pyrilamine systemic Brand names: Ninjacof-A Drug class (es): upper respiratory combinations Acetaminophen/chlophedianol/pyrilamine systemic is used in the treatment of: Cold Symptoms Coughacetaminophen/chlorpheniramine systemic Brand names: Coricidin HBP Cold & Flu, Congestant, 999 Cold Remedy Granular Drug class (es): upper respiratory combinations Acetaminophen/chlorpheniramine systemic is used in the treatment of: Allergic Rhinitis Cold Symptoms Influenza Rhinorrheaacetaminophen/chlorpheniramine/codeine systemic Brand names: Cotabflu Drug class (es): upper respiratory combinations Acetaminophen/chlorpheniramine/codeine systemic is used in the treatment of: Allergic Rhinitis Cold Symptoms Cough Cough and Nasal Congestionacetaminophen/chlorpheniramine/codeine/phenylephrine systemic Brand names: Colrex Compound, Colrex Drug class (es): upper respiratory combinationsacetaminophen/chlorpheniramine/dextromethorphan systemic Brand names: Triaminic Multi-Symptom Fever, Coricidin HBP Maximum Strength Flu, Vicks Ny Quil Cold & Flu Nighttime Relief (Alcohol Free), Tylenol Children’s Cold + Cough + Runny Nose Drug class (es): upper respiratory combinations Acetaminophen/chlorpheniramine/dextromethorphan systemic is used in the treatment of: Cold Symptoms Influenzaacetaminophen/chlorpheniramine/dextromethorphan/guaifenesin systemic Brand names: Coricidin HBP Day & Night Multi-Symptom Cold Drug class (es): upper respiratory combinations Acetaminophen/chlorpheniramine/dextromethorphan/guaifenesin systemic is used in the treatment of: Cold Symptomsacetaminophen/chlorpheniramine/dextromethorphan/guaifenesin/phenylephrine systemic Brand names: Tylenol Cold and Flu Severe Day & Night Drug class (es): upper respiratory combinations Acetaminophen/chlorpheniramine/dextromethorphan/guaifenesin/phenylephrine systemic is used in the treatment of: Cold Symptoms Coughacetaminophen/chlorpheniramine/dextromethorphan/phenylephrine systemic Brand names: Dimetapp Children's Multi-Symptom Cold & Flu (old formulation), Tylenol Children’s Cold + Flu, Alka-Seltzer Plus Cold & Cough Formula Liquid Gels, Pedia Care Multi-Symptom Cold Plus Acetaminophen Drug class (es): upper respiratory combinations Acetaminophen/chlorpheniramine/dextromethorphan/phenylephrine systemic is used in the treatment of: Cold Symptoms Cough Cough and Nasal Congestion Nasal Congestion Pain/Fever Rhinorrhea Sinus Symptomsacetaminophen/chlorpheniramine/dextromethorphan/phenylpropanolamine systemic Brand names: Comtrex Cold and Flu Maximum Strength, Comtrex Maximum Strength Cold Relief, Contac Severe Cold and Flu Maximum Stength Drug class (es): upper respiratory combinations Acetaminophen/chlorpheniramine/dextromethorphan/phenylpropanolamine systemic is used in the treatment of: Cold Symptomsacetaminophen/chlorpheniramine/dextromethorphan/pseudoephedrine systemic Brand names: Tylenol Cold, Theraflu Flu & Cough, Cough Formula M Multi-Symptom, Comtrex Cold and Flu Maximum Strength Tablet Drug class (es): upper respiratory combinations Acetaminophen/chlorpheniramine/dextromethorphan/pseudoephedrine systemic is used in the treatment of: Cold Symptoms Influenzaacetaminophen/chlorpheniramine/guaifenesin/phenylpropanolamine systemic Brand names: Gelpirin-CCF Drug class (es): upper respiratory combinationsacetaminophen/chlorpheniramine/phenylephrine systemic Brand names: Alka-Seltzer Plus Cold, Norel AD, Protid, Allergy Multi-Symptom Drug class (es): upper respiratory combinations Acetaminophen/chlorpheniramine/phenylephrine systemic is used in the treatment of: Cold Symptoms Sinus Symptomsacetaminophen/chlorpheniramine/phenylephrine/phenylpropanolamine/pyrilamine systemic Brand names: Covangesic Drug class (es): upper respiratory combinationsacetaminophen/chlorpheniramine/phenylephrine/phenyltoloxamine systemic Brand names: Norel SR, Trital SR Drug class (es): upper respiratory combinations Acetaminophen/chlorpheniramine/phenylephrine/phenyltoloxamine systemic is used in the treatment of: Cold Symptoms Nasal Congestionacetaminophen/chlorpheniramine/phenylephrine/salicylamide systemic Brand names: Rhinogesic Drug class (es): upper respiratory combinationsacetaminophen/chlorpheniramine/phenylpropanolamine systemic Brand names: Coricidin D, Sinulin, Alumadrine, Duadacin Drug class (es): upper respiratory combinations Acetaminophen/chlorpheniramine/phenylpropanolamine systemic is used in the treatment of: Cold Symptomsacetaminophen/chlorpheniramine/pseudoephedrine systemic Brand names: Sinarest, Sinutab Ex-Strength, Singlet, Comtrex Sinus and Nasal Drug class (es): upper respiratory combinations Acetaminophen/chlorpheniramine/pseudoephedrine systemic is used in the treatment of: Allergic Rhinitis Cold Symptomsacetaminophen/clemastine/pseudoephedrine systemic Brand names: Tavist Allergy/Sinus/Headache Drug class (es): upper respiratory combinationsacetaminophen/codeine systemic Brand names: Tylenol with Codeine #3, Tylenol with Codeine, Tylenol with Codeine #4, Aceta w/ Codeine Drug class (es): narcotic analgesic combinations Acetaminophen/codeine systemic is used in the treatment of: Cough Osteoarthritis Painacetaminophen/codeine/guaifenesin/phenylephrine systemic Brand names: Phenflu CDX, Phenflu CD Drug class (es): upper respiratory combinations Acetaminophen/codeine/guaifenesin/phenylephrine systemic is used in the treatment of: Cough and Nasal Congestionacetaminophen/codeine/guaifenesin/pseudoephedrine systemic Brand names: Maxiflu CD, Maxiflu CDX Drug class (es): upper respiratory combinations Acetaminophen/codeine/guaifenesin/pseudoephedrine systemic is used in the treatment of: Cold Symptoms Cough and Nasal Congestionacetaminophen/dexbrompheniramine systemic Brand names: Dologen, G-Dologen, Dologen 325, Actidogesic Drug class (es): upper respiratory combinations Acetaminophen/dexbrompheniramine systemic is used in the treatment of: Cold Symptomsacetaminophen/dexbrompheniramine/phenylephrine systemic Acetaminophen/dexbrompheniramine/phenylephrine systemic is used in the treatment of: Cold Symptomsacetaminophen/dexbrompheniramine/pseudoephedrine systemic Brand names: Drixoral Cold/Flu, Complete Sinus Relief, Sinadrin Plus, Drixoral Allergy Sinus Drug class (es): upper respiratory combinationsacetaminophen/dexchlorpheniramine/pseudoephedrine systemic Brand names: Hexafluacetaminophen/dextromethorphan systemic Brand names: Tylenol Cough and Sore Throat Daytime, Tylenol Children’s Cold + Cough + Sore Throat, Pedia Care Cough & Sore Throat Plus Acetaminophen, Triaminic Cough & Sore Throat Drug class (es): upper respiratory combinations Acetaminophen/dextromethorphan systemic is used in the treatment of: Cold Symptoms Coughacetaminophen/dextromethorphan/diphenhydramine systemic Brand names: Diabetic Tussin Night Time Formula, Diabetic Tussin Night Time Cold & Flu Drug class (es): upper respiratory combinations Acetaminophen/dextromethorphan/diphenhydramine systemic is used in the treatment of: Cold Symptoms Influenzaacetaminophen/dextromethorphan/diphenhydramine/phenylephrine systemic Brand names: Respa C&C, Respa C&C IR Drug class (es): upper respiratory combinations Acetaminophen/dextromethorphan/diphenhydramine/phenylephrine systemic is used in the treatment of: Cold Symptoms Nasal Congestionacetaminophen/dextromethorphan/diphenhydramine/pseudoephedrine systemic Brand names: Contac Day and Night Cold and Flu Drug class (es): upper respiratory combinations Acetaminophen/dextromethorphan/diphenhydramine/pseudoephedrine systemic is used in the treatment of: Cold Symptoms Influenzaacetaminophen/dextromethorphan/doxylamine systemic Brand names: Vicks Ny Quil Cold & Flu Nighttime Relief, Coricidin HBP Nighttime Multi-Symptom Cold, Robitussin Peak Cold Nighttime Cold + Flu, Contac Cold + Flu (Night) Cooling Relief Liquid Drug class (es): upper respiratory combinations Acetaminophen/dextromethorphan/doxylamine systemic is used in the treatment of: Cold Symptoms Coughacetaminophen/dextromethorphan/doxylamine/guaifenesin/phenylephrine systemic Brand names: Mucinex Fast-Max Day & Night, Mucinex Sinus-Max Day & Night Drug class (es): upper respiratory combinations Acetaminophen/dextromethorphan/doxylamine/guaifenesin/phenylephrine systemic is used in the treatment of: Cold Symptomsacetaminophen/dextromethorphan/doxylamine/phenylephrine systemic Brand names: Vicks Ny Quil Severe Cold & Flu, Delsym Night Time Multi-Symptom, Alka-Seltzer Plus Night Cold Formula Liquid Gels, Tylenol Cold Multi-Symptom Nighttime Liquid Drug class (es): upper respiratory combinations Acetaminophen/dextromethorphan/doxylamine/phenylephrine systemic is used in the treatment of: Cold Symptoms Cough Cough and Nasal Congestion Nasal Congestion Pain/Fever Rhinorrheaacetaminophen/dextromethorphan/doxylamine/pseudoephedrine systemic Brand names: Vicks Nyquil D Cold and Flu Nighttime Relief, All-Nite Cold, Tylenol Severe Cold & Flu Night Time, Multi-Symptom Nighttime Drug class (es): upper respiratory combinations Acetaminophen/dextromethorphan/doxylamine/pseudoephedrine systemic is used in the treatment of: Cold Symptomsacetaminophen/dextromethorphan/guaifenesin/phenylephrine systemic Brand names: Vicks Day Quil Severe Cold & Flu, Tylenol Cold & Flu Severe, Cough & Cold Relief, Tylenol Cold Multi-Symptom Severe Drug class (es): upper respiratory combinations Acetaminophen/dextromethorphan/guaifenesin/phenylephrine systemic is used in the treatment of: Cold Symptoms Influenzaacetaminophen/dextromethorphan/guaifenesin/phenylpropanolamine systemic Brand names: Anatuss Drug class (es): upper respiratory combinationsacetaminophen/dextromethorphan/guaifenesin/pseudoephedrine systemic Brand names: Duraflu, Robitussin Cold Cough and Flu, Tylenol Cold Severe Congestion Daytime, Phlemgesic Drug class (es): upper respiratory combinations Acetaminophen/dextromethorphan/guaifenesin/pseudoephedrine systemic is used in the treatment of: Cold Symptoms Cough and Nasal Congestionacetaminophen/dextromethorphan/phenylephrine systemic Brand names: Vicks Dayquil Cold & Flu Relief, Theraflu Daytime Severe Cold & Cough, Theraflu Multi-Symptom Severe Cold with Lipton Flavors, Tylenol Cold Max Day Drug class (es): upper respiratory combinations Acetaminophen/dextromethorphan/phenylephrine systemic is used in the treatment of: Cold Symptoms Cough Cough and Nasal Congestion Nasal Congestion Pain/Fever Sinus Symptomsacetaminophen/dextromethorphan/phenylpropanolamine systemic Brand names: Comtrex Non Drowsy Liquigel Drug class (es): upper respiratory combinationsacetaminophen/dextromethorphan/pseudoephedrine systemic Brand names: Vicks Dayquil Daytime Cold/Flu (old formulation), Theraflu (pseudoephedrine) Daytime Severe Cold, Severe Cold Multi-Symptom, Theraflu Flu Cold & Cough Drug class (es): upper respiratory combinations Acetaminophen/dextromethorphan/pseudoephedrine systemic is used in the treatment of: Cold Symptomsacetaminophen/dextromethorphan/pseudoephedrine/pyrilamine systemic Drug class (es): upper respiratory combinationsacetaminophen/dichloralphenazone/isometheptene mucate systemic Brand names: Midrin, Nodolor, Amidrine, Migratine Drug class (es): antimigraine agents Acetaminophen/dichloralphenazone/isometheptene mucate systemic is used in the treatment of: Headacheacetaminophen/diphenhydramine systemic Brand names: Tylenol PM, Acetaminophen PM Extra Strength, Acetadryl, Excedrin PM Drug class (es): analgesic combinations Acetaminophen/diphenhydramine systemic is used in the treatment of: Headache Insomnia Painacetaminophen/diphenhydramine/phenylephrine systemic Brand names: Theraflu Nighttime Severe Cold & Cough, CVS Allergy & Cold, Benadryl Allergy Plus Sinus Headache, Dimetapp Children's Multi-Symptom Cold & Flu Drug class (es): upper respiratory combinations Acetaminophen/diphenhydramine/phenylephrine systemic is used in the treatment of: Cold Symptomsacetaminophen/diphenhydramine/pseudoephedrine systemic Brand names: Benadryl Cold, Contac Day and Night Allergy, Sudafed Sinus Nighttime Plus Pain, Tylenol Allergy Complete Night Time Drug class (es): upper respiratory combinations Acetaminophen/diphenhydramine/pseudoephedrine systemic is used in the treatment of: Cold Symptoms Rhinitisacetaminophen/doxylamine/phenylephrine systemic Brand names: Vicks Qlear Quil Nighttime Sinus & Congestion, Alka-Seltzer Plus Severe Allergy Sinus Congestion & Headache, Vicks Sinex Nighttime Drug class (es): upper respiratory combinations Acetaminophen/doxylamine/phenylephrine systemic is used in the treatment of: Cold Symptoms Sinus Symptomsacetaminophen/doxylamine/pseudoephedrine systemic Brand names: Tylenol Sinus Night Time, Tylenol Sinus Day/Night Convenience Pack Drug class (es): upper respiratory combinations Acetaminophen/doxylamine/pseudoephedrine systemic is used in the treatment of: Nasal Congestion Sinus Symptomsacetaminophen/guaifenesin systemic Brand names: Tylenol Chest Congestion, Theraflu Flu & Chest Congestion, Comtrex Deep Chest Cold Drug class (es): upper respiratory combinations Acetaminophen/guaifenesin systemic is used in the treatment of: Cough Headache Painacetaminophen/guaifenesin/phenylephrine systemic Brand names: Beechams All-in-One, Mucinex Sinus-Max Pressure & Pain, Emagrin Forte, Sinus Congestion & Pain Drug class (es): upper respiratory combinations Acetaminophen/guaifenesin/phenylephrine systemic is used in the treatment of: Cough and Nasal Congestionacetaminophen/guaifenesin/pseudoephedrine systemic Brand names: Tylenol Sinus Severe Congestion Daytime, Sudafed Triple Action Drug class (es): upper respiratory combinations Acetaminophen/guaifenesin/pseudoephedrine systemic is used in the treatment of: Nasal Congestion Sinus Symptomsacetaminophen/hydrocodone systemic Brand names: Norco, Lortab, Vicodin, Lorcet Drug class (es): narcotic analgesic combinations Acetaminophen/hydrocodone systemic is used in the treatment of: Back Pain Cough Pain Rheumatoid Arthritisacetaminophen/magnesium salicylate systemic Brand names: Back Quell, Otis Clapp Back Quell Drug class (es): analgesic combinations Acetaminophen/magnesium salicylate systemic is used in the treatment of: Painacetaminophen/magnesium salicylate/pamabrom systemic Brand names: Pamprin Cramp Menstrual Pain Relief Drug class (es): analgesic combinations Acetaminophen/magnesium salicylate/pamabrom systemic is used in the treatment of: Period Painacetaminophen/oxycodone systemic Brand names: Percocet, Endocet, Percocet 5/325, Percocet 10/325 Drug class (es): narcotic analgesic combinations Acetaminophen/oxycodone systemic is used in the treatment of: Chronic Pain Painacetaminophen/pamabrom systemic Brand names: Midol, Backaid Max, Tylenol Women's Menstrual Relief, Midol Teen Drug class (es): analgesic combinations Acetaminophen/pamabrom systemic is used in the treatment of: Back Pain Premenstrual Dysphoric Disorder Premenstrual Syndromeacetaminophen/pamabrom/pyridoxine systemic Brand names: Lurline PMS Drug class (es): analgesic combinationsacetaminophen/pamabrom/pyrilamine systemic Brand names: Pamprin Multi-Symptom Menstrual Relief, Midol PMS Maximum Strength, Menstrual Pain Relief, Syncol Drug class (es): analgesic combinations Acetaminophen/pamabrom/pyrilamine systemic is used in the treatment of: Premenstrual Dysphoric Disorder Premenstrual Syndromeacetaminophen/pentazocine systemic Brand names: Talacen Drug class (es): narcotic analgesic combinations Acetaminophen/pentazocine systemic is used in the treatment of: Painacetaminophen/pheniramine/phenylephrine systemic Brand names: Theraflu Flu & Sore Throat, Theraflu Cold & Sore Throat, Theraflu Sinus & Cold, Scot-Tussin Original Drug class (es): upper respiratory combinations Acetaminophen/pheniramine/phenylephrine systemic is used in the treatment of: Cold Symptomsacetaminophen/phenylephrine systemic Brand names: Sudafed PE Pressure + Pain, Contac Cold + Flu (Day Formula), Alka-Seltzer Plus Cold and Sinus, Vicks Qlear Quil Daytime Sinus & Congestion Drug class (es): upper respiratory combinations Acetaminophen/phenylephrine systemic is used in the treatment of: Nasal Congestion Sinus Symptomsacetaminophen/phenyltoloxamine systemic Brand names: Dologesic, Rhino Flex, Percogesic, Vistra Drug class (es): analgesic combinations Acetaminophen/phenyltoloxamine systemic is used in the treatment of: Cold Symptoms Headache Influenza Painacetaminophen/phenyltoloxamine/salicylamide systemic Brand names: Anabar, Lobac, Dolorex, Duraxin Drug class (es): analgesic combinations Acetaminophen/phenyltoloxamine/salicylamide systemic is used in the treatment of: Painacetaminophen/propoxyphene systemic Brand names: Darvocet-N 50, Darvocet-N 100, Darvocet A500, Balacet Drug class (es): narcotic analgesic combinations Acetaminophen/propoxyphene systemic is used in the treatment of: Painacetaminophen/pseudoephedrine systemic Brand names: Sinus Relief, Ornex, Ornex Maximum Strength, Alka-Seltzer Cold and Sinus Drug class (es): upper respiratory combinations Acetaminophen/pseudoephedrine systemic is used in the treatment of: Sinus Symptomsacetaminophen/pseudoephedrine/triprolidine systemic Brand names: Actifed Cold and Sinus Drug class (es): upper respiratory combinations Acetaminophen/pseudoephedrine/triprolidine systemic is used in the treatment of: Cold Symptomsacetaminophen/pyrilamine systemic Brand names: Hista Flex Drug class (es): analgesic combinations Acetaminophen/pyrilamine systemic is used in the treatment of: Back Pain Headache Muscle Painacetaminophen/salicylamide systemic Brand names: Frenadol, Panritis Forte Drug class (es): analgesic combinationsacetaminophen/tramadol systemic Brand names: Ultracet, Tramapap Drug class (es): narcotic analgesic combinations Acetaminophen/tramadol systemic is used in the treatment of: Pain Rheumatoid Arthritis See 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