what is famvir prescribed for

Herpes infections are contagious and you can infect other people, even while you are being treated with famciclovir. Avoid letting infected areas come into contact with other people. Avoid touching an infected area and then touching your eyes. Wash your hands frequently to prevent passing the infection to others.

What Is Famciclovir?

What Is Famciclovir?1 Review Famciclovir is an antiviral drug.

It slows the growth and spread of the herpes virus so that the body can fight off the infection. Famciclovir will not cure herpes, but it can lessen the symptoms of the infections. Famciclovir is used to treat infections caused by herpes viruses, including genital herpes, cold sores, and shingles. There is no cure for herpes and famciclovir will not prevent you from developing symptoms in the future. Famciclovir may also be used for purposes not listed in this medication guide.

You should not take this medication if you are allergic to famciclovir or penciclovir cream (Denavir).

Take this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Treatment with famciclovir should be started as soon as possible after the first appearance of symptoms (such as tingling, burning, blisters).

on Exclusive of the antiretroviral agents used in HIV (AIDS) therapy, there are currently only 11 antiviral drugs available, covering four types of virus. Acyclovir (Zovirax), famciclovir (Famvir), andvalacyclovir (Valtrex) are effective against herpesvirus, including herpes zoster and herpesgenitalis.

Antiviral Drugs

"Antiviral Drugs Also found in: Dictionary, Thesaurus, Encyclopedia . Antiviral Drugs Definition Antiviral drugs are medicines that cure or control virus infections.

Purpose Antivirals are used to treat infections caused by viruses. Unlike antibacterial drugs, which maycover a wide range of pathogens, antiviral agents tend to be narrow in spectrum, and have limitedefficacy. Descripti

They may also be of value in either conditions caused by herpes, such as chickenpoxand shingles. These drugs are not curative, but may reduce the pain of a herpes outbreak andshorten the period of viral shedding. Amantadine (Symmetrel), oseltamivir (Tamiflu), rimantidine (Flumadine), and zanamivir (Relenza)are useful in treatment of influenza virus. Amantadine, rimantadine, and oseltamivir may be administered throughout the flu season as preventatives for patients who cannot take influenzavirus vaccine.

Key terms Asthenia — Muscle weakness. Cytomegalovirus (CMV) — A type of virus that attacks and enlarges certain cells in the body. The virus also causes a disease in infants. Herpes simplex — A virus that causes sores on the lips (cold sores) or on the genitals (genitalherpes).

HIV — Acronym for human immunodeficiency virus, the virus that causes AIDS. Parkinsonism — A group of conditions that all have these typical symptoms in common:tremor, rigidity, slow movement, and poor balance and coordination. Pregnancy category — A system of classifying drugs according to their established risks foruse during pregnancy. Category A: Controlled human studies have demonstrated no fetal risk. Category B: Animal studies indicate no fetal risk, but no human studies, or adverse effects in animals, but not in well-controlled human studies.

Category C: No adequate human or animalstudies, or adverse fetal effects in animal studies, but no available human data. Category D: Evidence of fetal risk, but benefits outweigh risks. Category X: Evidence of fetal risk.

Risksoutweigh any benefits. Prophylactic — Guarding from or preventing the spread or occurrence of disease or infection. Retrovirus — A group of viruses that contain RNA and the enzyme reverse transcriptase. Manyviruses in this family cause tumors.

The virus that causes AIDS is a retrovirus. Shingles — An disease caused by an infection with the Herpes zoster virus, the same virus thatcauses chickenpox. Symptoms of shingles include pain and blisters along one nerve, usually on the face, chest, stomach, or back.

Virus — A tiny, disease-causing structure that can reproduce only in living cells and causes a variety of infectious diseases. Cidofovir (Vistide), foscarnet (Foscavir), and ganciclovir (Cytovene) have been beneficial in treatment of cytomegalovirus in immunosupressed patients, primarily HIV-positive patients andtransplant recipients.

Ribavirin (Virazole) is used to treat respiratory syncytial virus. In combination with interferons, ribavirin has shown some efficacy against hepatitis C, and therehave been anecdotal reports of utility against other types of viral infections. As a class, the antivirals are not curative, and must be used either prophylactically or early in thedevelopment of an infection. Their mechanism of action is typically to inactivate the enzymesneeded for viral replication. This will reduce the rate of viral growth, but will not inactive the virusalready present.

Antiviral therapy must normally be initiated within 48 hours of the onset of an infection to provide any benefit. Drugs used for influenza may be used throughout the influenzaseason in high risk patients, or within 48 hours of exposure to a known carrier.

Antiherpeticagents should be used at the first signs of an outbreak. Anti-cytomegaloviral drugs mustroutinely be used as part of a program of secondary prophylaxis (maintenance therapy following an initial response) in order to prevent reinfection in immunocompromised patients.

Recommended dosage Dosage varies with the drug, patient age and condition, route of administration, and other factors. See specific references. Precautions Ganciclovir is available in intravenous injection, oral capsules, and intraoccular inserts. Thecapsules should be reserved for prophylactic use in organ transplant patients, or for HIV infectedpatients who cannot be treated with the intravenous drug. The toxicity profile of this drug whenadministered systemically includes granulocytopenia, anemia and thrombocytopenia.

The drug is in pregnancy category C, but has caused significant fetal abnormalities in animal studiesincluding cleft palate and organ defects. Breast feeding is not recommended. Cidofovir causes renal toxicity in 53% of patients. Patients should be well hydrated, and renalfunction should be checked regularly. Other common adverse effects are nausea and vomiting in 65% or patients, asthenia in 46% and headache and diarrhea, both reported in 27% of cases.

The drug is category C in pregnancy, due to fetal abnormalities in animal studies. Breast feeding is not recommended. Foscarnet is used in treatment of immunocompromised patients with cytomegalovirus infectionsand in acyclovir-resistant herpes simples virus.

The primary hazard is renal toxicity. Alterations in electrolyte levels may cause seizures. Foscarnet is category C during pregnancy. The drughas caused skeletal abnormailities in developing fetuses. It is not known whether foscarnet is excreted in breast milk, however the drug does appear in breast milk in animal studies.

Valaciclovir is metabolized to acyclovir, so that the hazards of the two drugs are very similar. They are generally well tolerated, but nausea and headache are common adverse effects. Theyare both pregnancy category B. Although there have been no reports of fetal abnormalitiesattributable to either drug, the small number of reported cases makes it impossible to drawconclusions regarding safety in pregnancy.

Acyclovir is found in breast milk, but no adverseeffects have been reported in the newborn. Famciclovir is similar in actions and adverse effects. Ribavirin is used by aerosol for treatment of hospitalized infants and young children with severelower respiratory tract infections due to respiratory syncytial virus (RSV).

When administeredorally, the drug has been used in adultys to treat other viral diseases including acute and chronichepatitis, herpes genitalis, measles, and Lassa fever, however there is relatively little informationabout these uses.

In rare cases, initiation of ribavirin therapy has led to deterioration of respiratory function in infants. Careful monitoring is essential for safe use. The anti-influenza drugs are generally well tolerated. Amantadine, which is also used fortreatment of Parkinsonism, may show more frequent CNS effects, including sedation anddizziness.

Rapid discontinuation of amantidine may cause an increase in Parkinsoniansymptoms in patients using the drug for that purpose. All are schedule C for pregnancy. In animal studies, they have caused fetal malformations in doses several times higher than thenormal human dose.

Use caution in breast feeding. Interactions Consult specific references for information on drug interactions. Use particular caution in HIV-positive patients, since these patients are commonly on multi-drugregimens with a high frequency of interactions. Ganciclovir should not be used with other drugswhich cause hematologic toxicity, and cidofovir should not be used with other drugs that maycause kidney damage.

Resources Periodicals Gray, Mary Ann. ""Antiviral Medications."" Orthopaedic Nursing 15 (November-December 1996):82. Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.antiviral1. effective against viruses.2. an agent effective against viruses.antiviral drugsmay be useful in early stages of some virus infections or to prevent recurrences or reactivation in chronic infections.

Most drugs exert their effects only during certain stages of viral replication and many are relatively toxic for the host when used systemically. In general, chemotherapy of virus infections in animals is uncommon with limitedapplications, mainly in topical treatment of ophthalmic infections. Examples areidoxuridine, vidarabine, amantadine hydrochloride, acyclovir, ribavirin. Saunders Comprehensive Veterinary Dictionary, 3 ed. © 2007 Elsevier, Inc. All rights reserved Want to thank TFD for its existence? Tell a friend about us, add a link to this page, or visit the webmaster's page for free fun content . Link to this page:Antiviral DrugsFacebook Twitter "

Famvir is now generic but still pricey. You have to take it twice a day. Some doc's prefer it but it's really not worth the price and twice a day effort unless you don't seem to be getting good results from valtrex/acyclovir. Acyclovir is the original oral herpes antiviral and is available as a cheap generic.

Is famvir better than valtrex

"Is famvir better than valtrex Common Questions and Answers about Is famvir better than valtrexfamvir Has anyone had better results with Famvir? And does it help suppress transmission like Valtrex does? My Dr thinks the Valtrex might be causing my hair loss so I am switching.... Read More Hi, I was wondering if one antiviral medication ( Valtrex /Zovirax/ Famvir) isbetter than the other?

I am currently on Valtrex 500mg QD for supressive therapy and all seems to be well (wood knock). Due to increasing prices/decreasing rx benefits, I am going to ask my gyn to possibly switch me to another medication that has a generic form. Valtrex is brand name only and will be (1/1/2009) costing me a $65 copay for a 90 day supply. If I switch to a generic, it would be a $10 copay.

Read More Thanks Grace, that's what I was thinking but it's nice to have a confirmation. I'm actually taking 200mg Acyclovir 4x per day (simply because that's what my pharmacy had available). Very inconvenient, but much less expensive than Valtrex. So, it sounds like if I take the Acyclovir as directed it will be as effective as Valtrex at reducing the risk of transmission.

Read More However, with my new partner i'm scared of transmitting it so i've started suppression therapy.

Does this really work? Is Famvir and Acyclovir just as effective (as far as transmission) ? Read More Is it ok to take more than one pill/treatment type for Herpes. I'm taking Valtrex 1 gm per day and also have started taking a pill from Herpaflor that contains Lysine, Purella Vulgaris, licorice root and vitamins A,C and zinc.

I'm doing a lot of research on the internet trying to learn what other herbs I can use to help prevent an outbreak. Is there something topical I can put on my upper lip and other areas that will prevent an outbreak from recurring there?

Read More But both times, I've gotten terrible side effects like nausea, headache, fatigue, dizziness/trouble concentrating. The side effects made me unable to work which unfortunately is worse than herpes symptoms themselves. My doctor said these side effects are possible but unusual and that maybe it's some inactive ingredient in the medicine and that I could try taking acyclovir instead to see if that helps without the side effects.

Read More Now 4 years later still have itchy balls, thighs itch but only a little, my balls are kinda bumpy, the skin on my balls is kinda leathery thick, I'm on famvir now still have itchy balls even when i take it, also I scratch in my sleep sometimes, it wakes me up, because my balls are to itchy, I scratch so much sometimes it leaves open sores then it gets more itchy, I try to keep clean down there but i sit down a lot causing me to get sweat between my thighs and and balls, the itch seems to wor Read More Is there any benefit to trying to switch medications, to say Famvir?

Or is there something else I should be concerned about with such frequent outbreaks even while on suppressive Valtrex? Also, as I have no Dr's here currently, should I just find a general family Dr? Or a Urologist to talk this over with?

Read Morehow would I know which was working.. I know the Valtrex is useful and the hbalm makes me feel better for at least an hour.. I probably won't buy any more hbalm, though. I think I have developed a hemorrhoid!! This is really starting to IRK ME!

I guess now I have to do research on that, too.... Is it common to have this happen after getting a herpes outbreak? My outbreak was mainly in the rectal area,,,should have known to leave dude alone after he tried going up there!!

Hindsight, hindsight... Read More Are you still engaging in intercourse while having outbreaks, maybe that is whey they aren't getting better. Also, I'm not sure what famvir is, but maybe it is stronger than Valtrex and will help you. You might just not respond to the one and that is why they are trying another.

Read More It seems your doctor is pretty sure you have HSV. But because it is the mouth, it is extremely unlikely that HSV-2 is the cause. Not only is oral HSV-2 rare, when it happens it almost always is in association with a simultaneous first infection with genital HSV-2. Since you have had no symptoms of genital herpes, your oral herpes surely is HSV-1. I don't understand the treatment with levofloxacin (Levaquin). That drug is totally ineffective against HSV. Read Morerash still present... On 5th day of Famvir now, still discomfort in left testicle... Is this herpes?

What else could it be? Worried about HIV, because of viral meds not working, but antibiotics not working either!...tested HIV negative 5 weeks ago at clinic.. Too early for seroconversion?

Please help!Read More I find it ironic because your telling me that Valtrex is better, but as you can see Grace has stated that there is really no diiference. I've read that their really was no difference a few times throughout some forums. Only difference is how often you actually TAKE the meds verses the effectiveness. I've been hearing that ALOT ""as you get older, the outbreaks decrease"". If you dont mind me asking, how long have you been dealing HSV2?

Read More You might benefit from a prescription for one of the oral anti-herpes drugs, like valacyclovir ( Valtrex ), famciclovir ( Famvir ), or acyclovir pills (also called Zovirax, plus other generic brands). Oral treatment would speed healing of the outbreaks much better than the ointment; or you could take the drug daily to prevent outbreaks entirely.

If and when the oral herpes diagnosis is confirmed, talk to your doctor or clinic about these treatments. I hope this helps. Read More09/08/07 HSVI Ig G = 59 UE/ml where 30 is + HSVI Ig M=20 UE/ml where 20 is + HSVII Ig G=43 UE/ml where 30 is + HSVII Ig M=18 UE/ml where 20 is + 09/19/07 Biopsy =compatible with HSV 11/10/07 HIV antibody test type I & 2 = - 1.

Do I have HSV? Are symptoms related to HSV? 2. How reliable are my blood test results, since reference values don't resemble anything posted before? 3. Can pap smear give false neg? What are the chances? 4. Can biopsy give false pos? What are the chances?

Is it conclusive? Read Moreacyclovir cream isn't very effective in general. it is actually recommended more so for oral herpes than genital herpes though it's usefulness is limited for both. Oral antivirals in the cold sore doses work better. plenty of cheaper and better topicals to apply to a cold sore for pain relief than acyclovir. Ask your provider for a prescription for oral acyclovir, famvir or valtrex in the cold sore doses and use an otc pain relief topical instead if the cold sore hurts. Read More You can't beat the convenience of once daily dosing and it's probably a little better drug than famvir ( longer time until shedding resumes when taking it suppressively ).

Famvir is now generic but still pricey. You have to take it twice a day. Some doc's prefer it but it's really not worth the price and twice a day effort unless you don't seem to be getting good results from valtrex/acyclovir. Acyclovir is the original oral herpes antiviral and is available as a cheap generic.

Read Moremy whole body aches and is sore. The fatigue is progressively getting worse. and yesterday I woke up with Bell's Palsy I am taking cymbalta, prednison and famvir now to help with the symptoms and Bell's palsy. Yet I feel like no one can understand what I am going through and no one seems to know what's wrong.

The term Chronic Epstain Barr Virus has been thrown around with my doctor but there is treatment for that and I can't accept that this is the way I will feel the rest of my life.

Read Morehas your wife had chicken pox in the past? did they put you on valtrex, acyclovir or famvir ? How were you diagnosed as having shingles? where is your rash located? Read Morewhat are you supposed to do after a year? 2. Is Famvir better than Valtrex ? 3. Are there any natural rememdies out there that seem to be effective?

I cant say that I am thrilled about taking prescription medication for the rest of my life to keep this disease at bay.

4. How close are we to a cure or at least some sort of shot where it will suppress the virus for years? 5. How common is asymptomatic shedding? Read More What mad eyou start suppressive therapy? You might want to consider switching to acyclovir or famvir instead and see if you do better on either of those. You can even start off at a low, subtheraputic dose and gradually increase your dose over the course of 2-3 weeks and see if you tolerate that better too.

Read More You can use acyclovir, valtrex or famvir for this. Just keep in mind that the antivirals work best when taken at the very first sign of a potential ob so if you start feeling that tell tale tingle/itch or whatever your prodrome is ( if you have one ) start the meds then. No need to wait until you have a full blown ob - the sooner you can start the meds the faster they work.

Some folks can even head off a full blown ob if they start medication early enough. Read Morecookie Set=1 It addresses why long term use of valtrex is thought to be just as safe as long term use of acyclovir ( acyclovir has been on the market way longer thanvaltrex though valtrex is an acyclovir prodrug ).

It's an excellent article if you've never taken the time to read it before. Also be aware that there's no need for any bloodwork to be done either if you are on antivirals long term.

They do not damage your kidney's or your liver. Read More Even though famvir is a generic now, it's still higher priced and you have to take it more often than valtrex so not really worth it unless you are one of the folks who just seems to do better on it. Even though valtrex is an acyclovir prodrug ( the body converts it to acyclovir), you get less active acyclovir in the actual acyclovir pill which is why you take it more often.

Read Moreis valtrex the only medicine that works for genital herpes? obviously nothing can get rid of it but is that the only medicine scientifically proven to help ? Read More Both acyclovir and famvir need to be taken twice daily for suppressive therapy ( acyclovir is 3x/day for ob's and famvir is still 2x/day for ob's ). Acyclovir is the cheapest choice. Read Morehow were you originally diagnosed as having herpes? Do you have hsv1 or hsv2 genitally?

have you been tested for yeast and bacterial infections vaginally in the last 3 months? diet and stress aren't really triggers for anyone. No need to do anything different than you usually do just because you have herpes. It's always a good idea to keep stress minimal but unfortunately real life didn't get that memo.

Read More We recommend the higher immunosuppression doses of valtrex and acyclovir during the last month of pregnancy. Your body is naturally immunosuppressed during pregnancy so it takes the higher doses to better control the virus.

since you were infected with hsv2 prior to pregnancy, the odds of transmission to your baby during birth are less than 1% as long as you don't have any obvious symptoms during delivery. Read More Lysine hasn't been shown to reduce outbreaks anymore better than anything else out there. There is not much proof either that outbreaks are caused by menstruation. If that was the case every female who has HSV would have an outbreak once a month. Read More Recommended "

Fortunately, there are safe and effective drugs for herpes. Commonly used for genital herpes, they can also be used to treat cold sores as well as to suppress future outbreaks. The oral prescription drugs are acyclovir (brand name Zovirax), valacyclovir (Valtrex) and famciclovir (Famvir), all available in generic form.

Lysine for Cold Sores?

ADVERTISEMENTThe herpes virus, an ancient and unwelcome human companion, comes in more than one form. Herpes simplex 1 is almost always the culprit in cold sores or fever blisters that erupt around the mouth; herpes simplex 2 is generally responsible for genital herpes. But, in fact, both forms of the virus can cause eruptions on the genitals and around the mouth. Herpes outbreaks are usually painful and unsightly, as well as contagious.

Anywhere from 60 to 90 percent of us carry herpes simplex 1, probably as a result of childhood infection. Genital herpes is one of the most common sexually transmitted infections. Once you have the virus, you have it.

It may lie dormant, but it doesn't go away. And it can be spread, even if you have no signs of the infection. In the 1980s, before there were effective drugs for herpes, the amino acid lysine was regarded as a potential treatment and preventive.

One of the building blocks of protein, lysine is supplied by many foods—notably red meats, fish and dairy products. You can certainly satisfy your needs for lysine from dietary sources. But to fight herpes, you would need more, the thinking ran. The idea that lysine might work against herpes has some plausibility. In order to replicate, the herpes virus requires arginine, another amino acid that's common in foods and necessary to human life; lysine is thought to interfere with the absorption of arginine in the intestine.

However, it's a long way from this observation to a herpes treatment, and most studies on high doses of lysine as a preventive or treatment have been inconclusive. While a few studies have found that lysine decreases the severity or duration of an outbreak, others have not.

In any case, most of the studies have been small and poorly designed. What's more, serious side effects (notably kidney problems) from long-term use have been reported; high doses can cause abdominal pain and diarrhea. We do not recommend lysine. Its effect is unproven, at best, and there are medications that work. A caution: If you do take lysine supplements, don't take them continually, but only when you feel cold sores coming on. Medication options for cold sores

Acyclovir is also available as a cream, as is another prescription drug, penciclovir (Denavir); the creams do not work as well as the oral medications. The cream docosanol (Abreva) is sold over the counter. These do not cure herpes in the sense that antibiotics cure bacterial infections, but do reduce the severity of outbreaks and have few, if any, serious side effects.

And long-term daily oral doses can cut down on recurrences. Final note: To head off cold sores, a sunscreen, applied to the lips daily, can be useful. Sunlight seems to activate herpes simplex 1 in some people. Published March 12, 2013

It slows the growth and spread of the herpes virus so that the body can fight off the infection. Famciclovir will not cure herpes, but it can lessen the symptoms of the infections. Famciclovir is used to treat infections caused by herpes viruses, including genital herpes, cold sores, and shingles. There is no cure for herpes and famciclovir will not prevent you from developing symptoms in the future. Famciclovir may also be used for purposes not listed in this medication guide.

What Is Famciclovir?

What Is Famciclovir?1 Review Famciclovir is an antiviral drug.

You should not take this medication if you are allergic to famciclovir or penciclovir cream (Denavir).

Take this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Treatment with famciclovir should be started as soon as possible after the first appearance of symptoms (such as tingling, burning, blisters).

Herpes infections are contagious and you can infect other people, even while you are being treated with famciclovir. Avoid letting infected areas come into contact with other people. Avoid touching an infected area and then touching your eyes. Wash your hands frequently to prevent passing the infection to others.

When famciclovir is used for shingles treatment, it will help the shingles rash heal more quickly. Famciclovir is not a cure for shingles, as the virus will always remain in your body and may become active again.

What Is Famciclovir Used For?

"Shingles Channel Topics & Medications Herpes Zoster Oticus Postherpetic Neuralgia Shingles Acyclovir Famciclovir Gabapentin Gralise Lidoderm Qutenza Valacyclovir Zostavax Advertisement Quicklinks Shingles Causes of Shingles Shingles Rash Symptoms of Shingles Shingles Treatment Shingles and Pregnancy Shingles Pain Cure for Shingles Postherpetic Neuralgia Acyclovir Famciclovir Gabapentin Gabapentin Side Effects Zostavax Lidoderm Patch Related Channels Chickenpox Osteoporosis Pain Senior Health Herpes Advertisement Tweet Shingles Home > What Is Famciclovir Used For?

What Is Famciclovir Used For? Famciclovir can be used to treat recurring cold sores, shingles, and recurring genital herpes.

The medicine is also used for treating herpes simplex infections in people with weak immune systems. ""Off-label"" famciclovir uses may include the treatment of other viral infections, such as chickenpox.

The medication has not been approved for use in children. Interested in a Discount on Famciclovir? Our free Discount Rx savings card can help you and your family save money on your prescriptions. This card is accepted at all major chain pharmacies, nationwide. Enter your name and email address to receive your free savings card. Enter Your Name Enter Your Email Address CLICK HERE to learn more about from e Med TV.com What Is Famciclovir Used For?

Famciclovir ( Famvir ®) is a prescription medication used for treating the following conditions: Shingles Recurring genital herpes Recurring cold sores Herpes simplex infections (including cold sores and genital herpes) in people with HIV or other conditions that weaken the immune system.

Famciclovir for Shingles Shingles (also known as herpes zoster) is caused by a virus (the varicella-zoster virus). It is the same virus that causes chickenpox. Most people were infected with this virus (as chickenpox) when they were children. The body never completely gets rid of the virus, and the virus remains inactive in certain nerve cells in the body.

Later in life, often triggered by stress or illness, the virus can become active again, causing shingles. Symptoms of shingles may include a rash (usually on only one side of the body) and burning or tingling pain.

Usually, the rash forms blisters that may break and ooze. If this happens, you may be able to spread the ""shingles virus"" to people who have never had chickenpox. Shingles pain can be very severe. It can continue long after the rash is gone (known medically as postherpetic neuralgia ). (Click Shingles Symptoms for more information about signs and symptoms of shingles. )

What Is Famciclovir Used For? Article Continues on Next Page >1 2 3 Next >>Advertisement Top Foods to Fight Inflammation Famciclovir Drug Information Famciclovir Side Effects of Famciclovir What Is Famciclovir Used For?

Famciclovir Dosing Drug Interactions With Famciclovir Precautions and Warnings With Famciclovir Last updated/reviewed: January 30, 2017List of references (click here)Written by/reviewed by: Kristi Monson, Pharm D; Arthur Schoenstadt, MDLast reviewed by: Kristi Monson, Pharm DFamciclovir Drug Information Famciclovir Side Effects of Famciclovir What Is Famciclovir Used For? Famciclovir Dosing Drug Interactions With Famciclovir Precautions and Warnings With Famciclovir Advertisement "

ges Uses Famciclovir is used to treat infections caused by certain types of viruses. It treats shingles caused by herpes zoster. It also treats outbreaks of herpes simplex that cause cold sores around the mouth, sores around the anus, and genital herpes. In people with frequent outbreaks of genital herpes, famciclovir is used to help reduce the number of future episodes. Famciclovir is an antiviral drug. However, it is not a cure for these infections. The viruses that cause these infections continue to live in the body even between outbreaks.

Famciclovir

Drugs & Medications Famciclovir COMMON BRAND (S): Famvir GENERIC NAME (S): Famciclovir Read Reviews (60)Uses Side Effects Precautions Interactions Overdose Ima

Famciclovir decreases the severity and length of these outbreaks. It helps the sores heal faster, keeps new sores from forming, and decreases pain/ itching.

This medication may also help reduce how long pain remains after the sores heal. In addition, in people with a weakened immune system, famciclovir can decrease the risk of the virus spreading to other parts of the body and causing serious infections. How to use Famciclovir Read the Patient Information Leaflet if available from your pharmacist before you start taking famciclovir and each time you get a refill.

If you have any questions, ask your doctor or pharmacist. Take this medication by mouth with or without food, usually 2 to 3 times a day or as directed by your doctor.

This medication works best when started at the first sign of an outbreak, as directed by your doctor. It may not work as well if you delay treatment. The dosage is based on your medical condition and response to treatment.

This medication works best when the amount of drug in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals. To help you remember, take it at the same times each day. Continue to take this medication until the full prescribed amount is finished.

Do not change your dose, skip any doses, or stop this medication early without your doctor's approval. Tell your doctor if your condition persists or worsens. Related Links What conditions does Famciclovir treat? Read More Next: Side Effects More Resources for famciclovir oral Check Interactions Read Reviews (60)

FAMVIR tablets contain 125 mg, 250 mg, or 500 mg of famciclovir, together with the following inactive ingredients: hydroxypropyl cellulose, hydroxypropyl methylcellulose, lactose, magnesium stearate, polyethylene glycols, sodium starch glycolate and titanium dioxide.

Famvir

"Drug Description Find Lowest Prices on FAMVIR (famciclovir) Tablets DESCRIPTIONThe active ingredient in FAMVIR tablets is famciclovir, an orally administered prodrug of the antiviral agent penciclovir. Chemically, famciclovir is known as 2- [2- (2-amino-9 H -purin-9-yl)ethyl]-1,3-propanediol diacetate.

Its molecular formula is C 14 H 19 N 5 O 4; its molecular weight is 321.3. It is a synthetic acyclic guanine derivative and has the following structure Famciclovir is a white to pale yellow solid.

It is freely soluble in acetone and methanol, and sparingly soluble in ethanol and isopropanol. At 25°C famciclovir is freely soluble (>25% w/v) in water initially, but rapidly precipitates as the sparingly soluble (2%-3% w/v) monohydrate. Famciclovir is not hygroscopic below 85% relative humidity. Partition coefficients are: octanol/water (p H 4.8) P=1.09 and octanol/phosphate buffer (p H 7.4) P =2.08.

For Consumers What are the possible side effects of famciclovir (Famvir)? Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using famciclovir and call your doctor at once if you have a serious side effect such as:urinating less than usual or not at all;weakness, confusion, increased thirst, loss of appetite, vomiting, pounding heartbeats or fluttering in your chest; orswelling, weight gain, feeling short of breath.

Less serious side effects may include:nausea, gas, stomach... Read All Potential Side Effects and See Pictures of Famvir »Sexually Transmitted Diseases (STDs) Slideshow Pictures Image Collection: Picture of Genital Warts (HPV)Take the Genital Herpes Quiz Indications & Dosage INDICATIONSImmunocompetent Adult Patients Herpes Labialis (Cold Sores)FAMVIR is indicated for the treatment of recurrent herpes labialis. Genital Herpes Recurrent episodes: FAMVIR is indicated for the treatment of recurrent episodes of genital herpes.

The efficacy of FAMVIR when initiated more than 6 hours after onset of symptoms or lesions has not been established. Suppressive therapy: FAMVIR is indicated for chronic suppressive therapy of recurrent episodes of genital herpes. The efficacy and safety of FAMVIR for the suppression of recurrent genital herpes beyond 1 year have not been established. Herpes Zoster (Shingles)FAMVIR is indicated for the treatment of herpes zoster. The efficacy of FAMVIR when initiated more than 72 hours after onset of rash has not been established.

HIV-Infected Adult Patients Recurrent Orolabial Or Genital Herpes FAMVIR is indicated for the treatment of recurrent episodes of orolabial or genital herpes in HIV -infected adults.

The efficacy of FAMVIR when initiated more than 48 hours after onset of symptoms or lesions has not been established. Limitation Of Use The efficacy and safety of FAMVIR have not been established for: Patients <18 years of age Patients with first episode of genital herpes Patients with ophthalmic zoster Immunocompromised patients other than for the treatment of recurrent orolabial or genital herpes in HIV-infected patients Black and African American patients with recurrent genital herpes DOSAGE AND ADMINISTRATIONFAMVIR may be taken with or without food.

Dosing Recommendation In Immunocompetent Adult Patients Herpes Labialis (Cold Sores)The recommended dosage of FAMVIR for the treatment of recurrent herpes labialis is 1500 mg as a single dose. Therapy should be initiated at the first sign or symptom of herpes labialis (e.g., tingling, itching, burning, pain, or lesion ).

Genital Herpes Recurrent episodes The recommended dosage of FAMVIR for the treatment of recurrent episodes of genital herpes is 1000 mg twice daily for 1 day.

Therapy should be initiated at the first sign or symptom of a recurrent episode (e.g., tingling, itching, burning, pain, or lesion). Suppressive therapy The recommended dosage of FAMVIR for chronic suppressive therapy of recurrent episodes of genital herpes is 250 mg twice daily.

Herpes Zoster (Shingles)The recommended dosage of FAMVIR for the treatment of herpes zoster is 500 mg every 8 hours for 7 days. Therapy should be initiated as soon as herpes zoster is diagnosed. Dosing Recommendation In HIV-Infected Adult Patients Recurrent Orolabial Or Genital Herpes The recommended dosage of FAMVIR for the treatment of recurrent orolabial or genital herpes in HIV-infected patients is 500 mg twice daily for 7 days.

Therapy should be initiated at the first sign or symptom of a recurrent episode (e.g., tingling, itching, burning, pain, or lesion). Dosing Recommendation In Patients With Renal Impairment Dosage recommendations for adult patients with renal impairment are provided in Table 1 [see Use In Specific Populations, CLINICAL PHARMACOLOGY ].

Table 1 Dosage Recommendations for Adult Patients with Renal Impairment Indication and Normal Dosage Regimen Creatinine Clearance (m L/min) Adjusted Dosage Regimen Dose (mg) Dosing Interval Single-Day Dosing Regimens Recurrent Genital Herpes 1000 mg every 12 hours for 1 day ≥60 1000 every 12 hours for 1 day40-59 500 every 12 hours for 1 day20-39 500 single dose<20 250 single dose HD* 250 single dose following dialysis Recurrent Herpes Labialis 1500 mg single dose ≥60 1500 single dose40-59 750 single dose20-39 500 single dose<20 250 single dose HD* 250 single dose following dialysis Multiple-Day Dosing Regimens Herpes Zoster ≥60 500 every 8 hours40-59 500 every 12 hours20-39 500 every 24 hours<20 250 every 24 hours HD* 250 following each dialysis Suppression of Recurrent Genital Herpes 250 mg every 12 hours ≥40 250 every 12 hours20-39 125 every 12 hours<20 125 every 24 hours HD* 125 following each dialysis Recurrent Orolabial or Genital Herpes in HIV-Infected Patients 500 mg every 12 hours ≥40 500 every 12 hours20-39 500 every 24 hours<20 250 every 24 hours HD* 250 following each dialysis*Hemodialysis HOW SUPPLIEDDosage Forms And Strengths FAMVIR tablets are available in 3 strengths:125 mg: White, round film-coated, biconvex, beveled edges, debossed with “FAMVIR” on one side and “125” on the other side250 mg: White, round film-coated, biconvex, beveled edges, debossed with “FAMVIR” on one side and “250” on the other side500 mg: White, oval film-coated, biconvex, debossed with “FAMVIR” on one side and “500” on the other side Storage And Handling FAMVIR tablets are supplied as film-coated tablets as follows: 125 mg in bottles of 30; 250 mg in bottles of 30; 500 mg in bottles of 30, and Single Unit Packages of 50 (intended for institutional use only).

FAMVIR 125 mg tablet: White, round film-coated, biconvex, beveled edges, debossed with “FAMVIR” on one side and “125” on the other.

125 mg 30’s NDC 0078-0366-15FAMVIR 250 mg tablet: White, round film-coated, biconvex, beveled edges, debossed with “FAMVIR” on one side and “250” on the other. 250 mg 30’s NDC 0078-0367-15FAMVIR 500 mg tablet: White, oval film-coated, biconvex, debossed with “FAMVIR” on one side and “500” on the other.

500 mg 30’s NDC 0078-0368-15 500 mg SUP 50’s NDC 0078-0368-64Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F) [see USP Controlled Room Temperature]. Distributed by: Novartis Pharmaceuticals Corporation, East Hanover, New Jersey 07936. Revised: Sep 2016Sexually Transmitted Diseases (STDs) Slideshow Pictures Image Collection: Picture of Genital Warts (HPV)Take the Genital Herpes Quiz Side Effects & Drug Interactions SIDE EFFECTSAcute renal failure is discussed in greater detail in other sections of the label [see WARNINGS AND PRECAUTIONS ].

The most common adverse events reported in at least 1 indication by >10% of adult patients treated with FAMVIR are headache and nausea.

Clinical Trials Experience In Adult Patients Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared with rates in the clinical trials of another drug and may not reflect the rates observed in practice.

Immunocompetent Patients The safety of FAMVIR has been evaluated in active-and placebo-controlled clinical studies involving 816 FAMVIR-treated patients with herpes zoster (FAMVIR, 250 mg three times daily to 750 mg three times daily); 163 FAMVIR-treated patients with recurrent genital herpes (FAMVIR, 1000 mg twice daily); 1,197 patients with recurrent genital herpes treated with FAMVIR as suppressive therapy (125 mg once daily to 250 mg three times daily) of which 570 patients received FAMVIR (open-labeled and/or double-blind) for at least 10 months; and 447 FAMVIR-treated patients with herpes labialis (FAMVIR, 1500 mg once daily or 750 mg twice daily).

Table 2 lists selected adverse events. Table 2 Selected Adverse Events (all grades and without regard to causality) Reported by ≥2% of Patients in Placebo-Controlled Famvir Trials*Incidence Events Herpes Zoster †Recurrent Genital Herpes ‡Genital Herpes-Suppression §Herpes Labialis ‡Famvir (n=273) % Placebo (n=146) % Famvir (n=163) % Placebo (n=166) % Famvir (n=458) % Placebo (n=63) % Famvir (n=447) % Placebo (n=254) %Nervous System Headache 22.7 17.8 13.5 5.4 39.3 42.9 8.5 6.7Paresthesia 2.6 0.0 0.0 0.0 0.9 0.0 0.0 0.0Migraine 0.7 0.7 0.6 0.6 3.1 0.0 0.2 0.0Gastrointestinal Nausea 12.5 11.6 2.5 3.6 7.2 9.5 2.2 3.9Diarrhea 7.7 4.8 4.9 1.2 9.0 9.5 1.6 0.8Vomiting 4.8 3.4 1.2 0.6 3.1 1.6 0.7 0.0Flatulence 1.5 0.7 0.6 0.0 4.8 1.6 0.2 0.0Abdominal Pain 1.1 3.4 0.0 1.2 7.9 7.9 0.2 0.4Body as a Whole Fatigue 4.4 3.4 0.6 0.0 4.8 3.2 1.6 0.4Skin and Appendages Pruritus 3.7 2.7 0.0 0.6 2.2 0.0 0.0 0.0Rash 0.4 0.7 0.0 0.0 3.3 1.6 0.0 0.0Reproductive (Female)Dysmenorrhea 0.0 0.7 1.8 0.6 7.6 6.3 0.4 0.0*Patients may have entered into more than one clinical trial.

† 7 days of treatment ‡ 1 day of treatment § daily treatment Table 3 lists selected laboratory abnormalities in genital herpes suppression trials.

Table 3 Selected Laboratory Abnormalities in Genital Herpes Suppression Studies*Parameter Famvir (n=660) † % Placebo (n=210) † %Anemia (<0.8 x NRL) 0.1 0.0Leukopenia (<0.75 x NRL) 1.3 0.9Neutropenia (<0.8 x NRL) 3.2 1.5AST (SGOT) (>2 x NRH) 2.3 1.2ALT (SGPT) (>2 x NRH) 3.2 1.5Total Bilirubin (>1.5 x NRH) 1.9 1.2Serum Creatinine (>1.5 x NRH) 0.2 0.3Amylase (>1.5 x NRH) 1.5 1.9Lipase (>1.5 x NRH) 4.9 4.7*Percentage of patients with laboratory abnormalities that were increased or decreased from baseline and were outside of specified ranges. † n values represent the minimum number of patients assessed for each laboratory parameter. NRH=Normal Range High.

NRL=Normal Range Low. HIV-Infected Patients In HIV-infected patients, the most frequently reported adverse events for FAMVIR (500 mg twice daily; n=150) and acyclovir (400 mg, 5x/day; n=143), respectively, were headache (17% vs. 15%), nausea (11% vs. 13%), diarrhea (7% vs. 11%), vomiting (5% vs. 4%), fatigue (4% vs. 2%), and abdominal pain (3% vs. 6%).

Postmarketing Experience The adverse events listed below have been reported during postapproval use of FAMVIR.

Because these events are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure: Blood and lymphatic system disorders: Thrombocytopenia Hepatobiliary disorders: Abnormal liver function tests, cholestatic jaundice Immune system disorders: Anaphylactic shock, anaphylactic reaction Nervous system disorders: Dizziness, somnolence, seizure Psychiatric disorders: Confusion (including delirium, disorientation, and confusional state occurring predominantly in the elderly), hallucinations Skin and subcutaneous tissue disorders: Urticaria, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, angioedema (e.g., face, eyelid, periorbital, and pharyngeal edema), hypersensitivity vasculitis Cardiac disorders: Palpitations DRUG INTERACTIONSPotential For FAMVIR To Affect Other Drugs The steady-state pharmacokinetics of digoxin were not altered by concomitant administration of multiple doses of famciclovir (500 mg three times daily).

No clinically significant effect on the pharmacokinetics of zidovudine, its metabolite zidovudine glucuronide, or emtricitabine was observed following a single oral dose of 500 mg famciclovir coadministered with zidovudine or emtricitabine. An in vitro study using human liver microsomes suggests that famciclovir is not an inhibitor of CYP3A4 enzymes.

Potential For Other Drugs To Affect Penciclovir No clinically significant alterations in penciclovir pharmacokinetics were observed following single-dose administration of 500 mg famciclovir after pretreatment with multiple doses of allopurinol, cimetidine, theophylline, zidovudine, promethazine, when given shortly after an antacid (magnesium and aluminum hydroxide), or concomitantly with emtricitabine. No clinically significant effect on penciclovir pharmacokinetics was observed following multiple-dose (three times daily) administration of famciclovir (500 mg) with multiple doses of digoxin.

Concurrent use with probenecid or other drugs significantly eliminated by active renal tubular secretion may result in increased plasma concentrations of penciclovir. The conversion of 6-deoxy penciclovir to penciclovir is catalyzed by aldehyde oxidase. Interactions with other drugs metabolized by this enzyme and/or inhibiting this enzyme could potentially occur.

Clinical interaction studies of famciclovir with cimetidine and promethazine, in vitro inhibitors of aldehyde oxidase, did not show relevant effects on the formation of penciclovir. Raloxifene, a potent aldehyde oxidase inhibitor in vitro, could decrease the formation of penciclovir.

However, a clinical drug-drug interaction study to determine the magnitude of interaction between penciclovir and raloxifene has not been conducted. Sexually Transmitted Diseases (STDs) Slideshow Pictures Image Collection: Picture of Genital Warts (HPV)Take the Genital Herpes Quiz Warnings & Precautions WARNINGSIncluded as part of the ""PRECAUTIONS"" Section PRECAUTIONSAcute Renal Failure Cases of acute renal failure have been reported in patients with underlying renal disease who have received inappropriately high doses of FAMVIR for their level of renal function.

Dosage reduction is recommended when administering FAMVIR to patients with renal impairment [see DOSAGE AND ADMINISTRATION, Use In Specific Populations ]. Patient Counseling Information Advise the patient to read the FDA-approved patient labeling (Patient Information). There is no evidence that FAMVIR will affect the ability of a patient to drive or to use machines. However, patients who experience dizziness, somnolence, confusion or other central nervous system disturbances while taking FAMVIR should refrain from driving or operating machinery. Because FAMVIR contains lactose (FAMVIR 125 mg, 250 mg, and 500 mg tablets contain lactose 26.9 mg, 53.7 mg and 107.4 mg, respectively), patients with rare hereditary problems of galactose intolerance, a severe lactase deficiency or glucose-galactose malabsorption should be advised to discuss with their healthcare provider before taking FAMVIR.

Herpes Labialis (Cold Sores)Patients should be advised to initiate treatment at the earliest sign or symptom of a recurrence of cold sores (e.g., tingling, itching, burning, pain, or lesion ).

Patients should be instructed that treatment for cold sores should not exceed 1 dose. Patients should be informed that FAMVIR is not a cure for cold sores. Genital Herpes Patients should be informed that FAMVIR is not a cure for genital herpes. There are no data evaluating whether FAMVIR will prevent transmission of infection to others. Because genital herpes is a sexually transmitted disease, patients should avoid contact with lesions or intercourse when lesions and/or symptoms are present to avoid infecting partners.

Genital herpes is frequently transmitted in the absence of symptoms through asymptomatic viral shedding.

Therefore, patients should be counseled to use safer sex practices. If episodic therapy for recurrent genital herpes is indicated, patients should be advised to initiate therapy at the first sign or symptom of an episode. There are no data on safety or effectiveness of chronic suppressive therapy of longer than 1-year duration.

Herpes Zoster (Shingles)There are no data on treatment initiated more than 72 hours after onset of zoster rash. Patients should be advised to initiate treatment as soon as possible after a diagnosis of herpes zoster. Nonclinical Toxicology Carcinogenesis, Mutagenesis, Impairment Of Fertility Carcinogenesis Two-year dietary carcinogenicity studies with famciclovir were conducted in rats and mice.

An increase in the incidence of mammary adenocarcinoma (a common tumor in animals of this strain) was seen in female rats receiving the high dose of 600 mg/kg/day (1.1 to 4.5x the human systemic exposure at the recommended total daily oral dose ranging between 500 mg and 2000 mg, based on area under the plasma concentration curve comparisons [24 hr AUC] for penciclovir).

No increases in tumor incidence were reported in male rats treated at doses up to 240 mg/kg/day (0.7 to 2.7x the human AUC), or in male and female mice at doses up to 600 mg/kg/day (0.3 to 1.2x the human AUC). Mutagenesis Famciclovir and penciclovir (the active metabolite of famciclovir) were tested for genotoxic potential in a battery of in vitro and in vivo assays.

Famciclovir and penciclovir were negative in in vitro tests for gene mutations in bacteria ( S. typhimurium and E. coli) and unscheduled DNA synthesis in mammalian He La 83 cells (at doses up to 10,000 and 5,000 mcg/plate, respectively). Famciclovir was also negative in the L5178Y mouse lymphoma assay (5000 mcg/m L), the in vivo mouse micronucleus test (4800 mg/kg), and rat dominant lethal study (5000 mg/kg).

Famciclovir induced increases in polyploidy in human lymphocytes in vitro in the absence of chromosomal damage (1200 mcg/m L). Penciclovir was positive in the L5178Y mouse lymphoma assay for gene mutation/chromosomal aberrations, with and without metabolic activation (1000 mcg/m L).

In human lymphocytes, penciclovir caused chromosomal aberrations in the absence of metabolic activation (250 mcg/m L). Penciclovir caused an increased incidence of micronuclei in mouse bone marrow in vivo when administered intravenously at doses highly toxic to bone marrow (500 mg/kg), but not when administered orally.

Impairment Of Fertility Testicular toxicity was observed in rats, mice, and dogs following repeated administration of famciclovir or penciclovir. Testicular changes included atrophy of the seminiferous tubules, reduction in sperm count, and/or increased incidence of sperm with abnormal morphology or reduced motility.

The degree of toxicity to male reproduction was related to dose and duration of exposure. In male rats, decreased fertility was observed after 10 weeks of dosing at 500 mg/kg/day (1.4 to 5.7x the human AUC). The no observable effect level for sperm and testicular toxicity in rats following chronic administration (26 weeks) was 50 mg/kg/day (0.15 to 0.6x the human systemic exposure based on AUC comparisons).

Testicular toxicity was observed following chronic administration to mice (104 weeks) and dogs (26 weeks) at doses of 600 mg/kg/day (0.3 to 1.2x the human AUC) and 150 mg/kg/day (1.3 to 5.1x the human AUC), respectively. Famciclovir had no effect on general reproductive performance or fertility in female rats at doses up to 1000 mg/kg/day (2.7 to 10.8x the human AUC).

Two placebo-controlled studies in a total of 130 otherwise healthy men with a normal sperm profile over an 8-week baseline period and recurrent genital herpes receiving oral FAMVIR (250 mg twice daily) (n=66) or placebo (n=64) therapy for 18 weeks showed no evidence of significant effects on sperm count, motility or morphology during treatment or during an 8-week follow-up.

Use In Specific Populations Pregnancy Pregnancy Category BAfter oral administration, famciclovir ( prodrug) is converted to penciclovir (active drug).

There are no adequate and well-controlled studies of famciclovir or penciclovir use in pregnant women. No adverse effects on embryofetal development were observed in animal reproduction studies using famciclovir and penciclovir at doses higher than the maximum recommended human dose (MRHD) and human exposure. Because animal reproduction studies are not always predictive of human response, famciclovir should be used during pregnancy only if needed.

In animal reproduction studies, pregnant rats and rabbits received oral famciclovir at doses (up to 1000 mg/kg/day) that provided 2.7 to 10.8 times (rats) and 1.4 to 5.4 times (rabbits) the human systemic exposure based on AUC.

No adverse effects were observed on embryo-fetal development. In other studies, pregnant rats and rabbits received intravenous famciclovir at doses (360 mg/kg/day) 1.5 to 6 times (rats) and (120 mg/kg/day) 1.1 to 4.5 times (rabbits) or penciclovir at doses (80 mg/kg/day) 0.3 to 1.3 times (rats) and (60 mg/kg/day) 0.5 to 2.1 times (rabbits) the MRHD based on body surface area comparisons.

No adverse effects were observed on embryo-fetal development. Pregnancy Exposure Reporting To monitor maternal-fetal outcomes of pregnant women exposed to FAMVIR, Novartis Pharmaceuticals Corporation maintains a FAMVIR Pregnancy Reporting system. Physicians are encouraged to report their patients by calling 1-888-NOW-NOVA (669-6682). Nursing Mothers It is not known whether famciclovir (prodrug) or penciclovir (active drug) are excreted in human milk.

Following oral administration of famciclovir to lactating rats, penciclovir was excreted in breast milk at concentrations higher than those seen in the plasma.

There are no data on the safety of FAMVIR in infants. FAMVIR should not be used in nursing mothers unless the potential benefits are considered to outweigh the potential risks associated with treatment. Pediatric Use The efficacy of FAMVIR has not been established in pediatric patients. The pharmacokinetic profile and safety of famciclovir (experimental granules mixed with Ora Sweet ® or tablets) were studied in 3 open-label studies.

Study 1 was a single-dose pharmacokinetic and safety study in infants 1 month to <1 year of age who had an active herpes simplex virus (HSV) infection or who were at risk for HSV infection. Eighteen subjects were enrolled and received a single dose of famciclovir experimental granules mixed with Ora Sweet based on the patient’s body weight (doses ranged from 25 mg to 175 mg).

These doses were selected to provide penciclovir systemic exposures similar to the penciclovir systemic exposures observed in adults after administration of 500 mg famciclovir. The efficacy and safety of famciclovir have not been established as suppressive therapy in infants following neonatal HSV infections. In addition, the efficacy cannot be extrapolated from adults to infants because there is no similar disease in adults.

Therefore, famciclovir is not recommended in infants. Study 2 was an open-label, single-dose pharmacokinetic, multiple-dose safety study of famciclovir experimental granules mixed with Ora Sweet in children 1 to <12 years of age with clinically suspected HSV or varicella zoster virus (VZV) infection. Fifty-one subjects were enrolled in the pharmacokinetic part of the study and received a single body weight adjusted dose of famciclovir (doses ranged from 125 mg to 500 mg).

These doses were selected to provide penciclovir systemic exposures similar to the penciclovir systemic exposures observed in adults after administration of 500 mg famciclovir. Based on the pharmacokinetic data observed with these doses in children, a new weight-based dosing algorithm was designed and used in the multiple-dose safety part of the study.

Pharmacokinetic data were not obtained with the revised weight-based dosing algorithm. A total of 100 patients were enrolled in the multiple-dose safety part of the study; 47 subjects with active or latent HSV infection and 53 subjects with chickenpox.

Patients with active or latent HSV infection received famciclovir twice a day for 7 days. The daily dose of famciclovir ranged from 150 mg to 500 mg twice daily depending on the patient’s body weight. Patients with chickenpox received famciclovir three times daily for 7 days. The daily dose of famciclovir ranged from 150 mg to 500 mg three times daily depending on the patient’s body weight.

The clinical adverse events and laboratory test abnormalities observed in this study were similar to these seen in adults.

The available data are insufficient to support the use of famciclovir for the treatment of children 1 to <12 years of age with chickenpox or infections due to HSV for the following reasons: Chickenpox The efficacy of famciclovir for the treatment of chickenpox has not been established in either pediatric or adult patients. Famciclovir is approved for the treatment of herpes zoster in adult patients. However, extrapolation of efficacy data from adults with herpes zoster to children with chickenpox would not be appropriate.

Although chickenpox and herpes zoster are caused by the same virus, the diseases are different. Genital Herpes Clinical information on genital herpes in children is limited. Therefore, efficacy data from adults cannot be extrapolated to this population. Further, famciclovir has not been studied in children 1 to <12 years of age with recurrent genital herpes.

None of the children in Study 2 had genital herpes. Herpes Labialis There are no pharmacokinetic and safety data in children 1 to <12 years of age to support a famciclovir dose that provides penciclovir systemic exposures comparable to the penciclovir systemic exposures in adults after a single dose administration of 1500 mg. Moreover, no efficacy data have been obtained in children 1 to <12 years of age with recurrent herpes labialis.

Study 3 was an open-label, single-arm study to evaluate the pharmacokinetics, safety, and antiviral activity of a single 1500 mg dose (three 500 mg tablets) of famciclovir in children 12 to <18 years of age with recurrent herpes labialis.

A total of 53 subjects were enrolled in the study; 10 subjects in the pharmacokinetic part of the study and 43 subjects in the non-pharmacokinetic part of the study. All enrolled subjects weighed ≥40 kg. The 43 subjects enrolled in the nonpharmacokinetic part of the study had active recurrent herpes labialis and received a single 1500 mg dose of famciclovir within 24 hours after the onset of symptoms (median time to treatment initiation was 21 hours).

The safety profile of famciclovir observed in this study was similar to that seen in adults. The median time to healing of patients with non-aborted lesions was 5.9 days.

In a phase 3 trial in adults in which patients received a single 1500 mg dose of famciclovir or placebo, the median time to healing among patients with non-aborted lesions was 4.4 days in the famciclovir 1500 mg single-dose group and 6.2 days in the placebo group.

Of note, in the adult study treatment was initiated by patients within 1 hour after the onset of symptoms [see Clinical Studies ]. Based on the efficacy results in Study 3, famciclovir is not recommended in children 12 to <18 years of age with recurrent herpes labialis.

Geriatric Use Of 816 patients with herpes zoster in clinical studies who were treated with FAMVIR, 248 (30.4%) were ≥65 years of age and 103 (13%) were ≥75 years of age. No overall differences were observed in the incidence or types of adverse events between younger and older patients.

Of 610 patients with recurrent herpes simplex (type 1 or type 2) in clinical studies who were treated with FAMVIR, 26 (4.3%) were >65 years of age and 7 (1.1%) were >75 years of age. Clinical studies of FAMVIR in patients with recurrent genital herpes did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently compared to younger subjects.

No famciclovir dosage adjustment based on age is recommended unless renal function is impaired [see DOSAGE AND ADMINISTRATION, CLINICAL PHARMACOLOGY ]. In general, appropriate caution should be exercised in the administration and monitoring of FAMVIR in elderly patients reflecting the greater frequency of decreased renal function and concomitant use of other drugs. Patients With Renal Impairment Apparent plasma clearance, renal clearance, and the plasma-elimination rate constant of penciclovir decreased linearly with reductions in renal function.

After the administration of a single 500 mg famciclovir oral dose (n=27) to healthy volunteers and to volunteers with varying degrees of renal impairment (CL CR ranged from 6.4 to 138.8 m L/min), the following results were obtained (Table 4): Table 4 Pharmacokinetic Parameters of Penciclovir in Subjects with Different Degrees of Renal Impairment Parameter (mean ± S. D.) CL CR † ≥60 (m L/min) (n=15) CL CR 40-59 (m L/min) (n=5) CL CR 20-39 (m L/min) (n=4) CL CR <20 (m L/min) (n=3)CL CR (m L/min) 88.1 ± 20.6 49.3 ± 5.9 26.5 ± 5.3 12.7 ± 5.9CLR (L/hr) 30.1 ± 10.6 13.0 ± 1.3 ‡ 4.2 ± 0.9 1.6 ± 1.0CL/F § (L/hr) 66.9 ± 27.5 27.3 ± 2.8 12.8 ± 1.3 5.8 ± 2.8Half-life (hr) 2.3 ± 0.5 3.4 ± 0.7 6.2 ± 1.6 13.4 ± 10.2† CL CR is measured creatinine clearance.

‡ n=4. § CL/F consists of bioavailability factor and famciclovir to penciclovir conversion factor. In a multiple-dose study of famciclovir conducted in subjects with varying degrees of renal impairment (n=18), the pharmacokinetics of penciclovir were comparable to those after single doses.

A dosage adjustment is recommended for patients with renal impairment [see DOSAGE AND ADMINISTRATION ]. Patients With Hepatic Impairment Mild or moderate hepatic impairment (chronic hepatitis [n=6], chronic ethanol abuse [n=8], or primary biliary cirrhosis [n=1]) had no effect on the extent of availability (AUC) of penciclovir following a single dose of 500 mg famciclovir.

However, there was a 44% decrease in penciclovir mean maximum plasma concentration (Cmax) and the time to maximum plasma concentration (tmax) was increased by 0.75 hours in patients with hepatic impairment compared to normal volunteers. No dosage adjustment is recommended for patients with mild or moderate hepatic impairment. The pharmacokinetics of penciclovir has not been evaluated in patients with severe hepatic impairment. Conversion of famciclovir to the active metabolite penciclovir may be impaired in these patients resulting in a lower penciclovir plasma concentrations, and thus possibly a decrease of efficacy of famciclovir [see CLINICAL PHARMACOLOGY ].

Black And African American Patients In a randomized, double-blind, placebo-controlled trial conducted in 304 immunocompetent black and African American adults with recurrent genital herpes there was no difference in median time to healing between patients receiving FAMVIR or placebo. In general, the adverse reaction profile was similar to that observed in other FAMVIR clinical trials for adult patients [see ADVERSE REACTIONS ].

The relevance of these study results to other indications in black and African American patients is unknown [see Clinical Studies ]. Sexually Transmitted Diseases (STDs) Slideshow Pictures Image Collection: Picture of Genital Warts (HPV)Take the Genital Herpes Quiz Overdosage & Contraindications OVERDOSEAppropriate symptomatic and supportive therapy should be given. Penciclovir is removed by hemodialysis. CONTRAINDICATIONSFAMVIR is contraindicated in patients with known hypersensitivity to the product, its components, or Denavir ® (penciclovir cream).

Sexually Transmitted Diseases (STDs) Slideshow Pictures Image Collection: Picture of Genital Warts (HPV)Take the Genital Herpes Quiz Clinical Pharmacology CLINICAL PHARMACOLOGYMechanism Of Action Famciclovir is an orally administered prodrug of the antiviral agent penciclovir [see Microbiology ].

Pharmacokinetics Famciclovir is the diacetyl 6-deoxy analog of the active antiviral compound penciclovir. Following oral administration famciclovir undergoes rapid and extensive metabolism to penciclovir and little or no famciclovir is detected in plasma or urine.

Penciclovir is predominantly eliminated unchanged by the kidney. Therefore, the dose of FAMVIR needs to be adjusted in patients with different degrees of renal impairment [see DOSAGE AND ADMINISTRATION ]. Pharmacokinetics In Adults Absorption and Bioavailability: The absolute bioavailability of penciclovir is 77 ± 8% as determined following the administration of a 500 mg famciclovir oral dose and a 400 mg penciclovir intravenous dose to 12 healthy male subjects.

Penciclovir concentrations increased in proportion to dose over a famciclovir dose range of 125 mg to 1000 mg administered as a single dose. Table 5 shows the mean pharmacokinetic parameters of penciclovir after single administration of FAMVIR to healthy male volunteers.

Table 5 Mean Pharmacokinetic Parameters of Penciclovir in Healthy Adult Subjects*Dose AUC (0-inf) † (mcg hr/m L) Cmax ‡ (mcg/m L) tmax § (h)125 mg 2.24 0.8 0.9250 mg 4.48 1.6 0.9500 mg 8.95 3.3 0.91000 mg 17.9 6.6 0.9* Based on pharmacokinetic data from 17 studies † AUC (0-inf) (mcg hr/m L)=area under the plasma concentration-time profile extrapolated to infinity.

‡ Cmax (mcg/m L)=maximum observed plasma concentration. § tmax (h)= time to Cmax. Following oral single-dose administration of 500 mg famciclovir to 7 patients with herpes zoster, the AUC (mean ± SD), Cmax, and tmax were 12.1±1.7 mcg hr/m L, 4.0±0.7 mcg/m L, and 0.7±0.2 hours, respectively.

The AUC of penciclovir was approximately 35% greater in patients with herpes zoster as compared to healthy volunteers. Some of this difference may be due to differences in renal function between the 2 groups. There is no accumulation of penciclovir after the administration of 500 mg famciclovir three times daily for 7 days.

Penciclovir Cmax decreased approximately 50% and tmax was delayed by 1.5 hours when a capsule formulation of famciclovir was administered with food (nutritional content was approximately 910 Kcal and 26% fat). There was no effect on the extent of availability (AUC) of penciclovir. There was an 18% decrease in Cmax and a delay in tmax of about 1 hour when famciclovir was given 2 hours after a meal as compared to its administration 2 hours before a meal. Because there was no effect on the extent of systemic availability of penciclovir, FAMVIR can be taken without regard to meals.

Distribution: The volume of distribution (Vdβ) was 1.08±0.17 L/kg in 12 healthy male subjects following a single intravenous dose of penciclovir at 400 mg administered as a 1-hour intravenous infusion. Penciclovir is <20% bound to plasma proteins over the concentration range of 0.1 to 20 mcg/m L. The blood/plasma ratio of penciclovir is approximately 1. Metabolism: Following oral administration, famciclovir is deacetylated and oxidized to form penciclovir.

Metabolites that are inactive include 6-deoxy penciclovir, monoacetylated penciclovir, and 6-deoxy monoacetylated penciclovir (5%, <0.5% and <0.5% of the dose in the urine, respectively). Little or no famciclovir is detected in plasma or urine. An in vitro study using human liver microsomes demonstrated that cytochrome P450 does not play an important role in famciclovir metabolism.

The conversion of 6-deoxy penciclovir to penciclovir is catalyzed by aldehyde oxidase. Cimetidine and promethazine, in vitro inhibitors of aldehyde oxidase, did not show relevant effects on the formation of penciclovir in vivo [see DRUG INTERACTIONS ].

Elimination: Approximately 94% of administered radioactivity was recovered in urine over 24 hours (83% of the dose was excreted in the first 6 hours) after the administration of 5 mg/kg radiolabeled penciclovir as a 1-hour infusion to 3 healthy male volunteers.

Penciclovir accounted for 91% of the radioactivity excreted in the urine. Following the oral administration of a single 500 mg dose of radiolabeled famciclovir to 3 healthy male volunteers, 73% and 27% of administered radioactivity were recovered in urine and feces over 72 hours, respectively. Penciclovir accounted for 82% and 6-deoxy penciclovir accounted for 7% of the radioactivity excreted in the urine.

Approximately 60% of the administered radiolabeled dose was collected in urine in the first 6 hours. After intravenous administration of penciclovir in 48 healthy male volunteers, mean ± SD total plasma clearance of penciclovir was 36.6±6.3 L/hr (0.48±0.09 L/hr/kg).

Penciclovir renal clearance accounted for 74.5±8.8% of total plasma clearance. Renal clearance of penciclovir following the oral administration of a single 500 mg dose of famciclovir to 109 healthy male volunteers was 27.7±7.6 L/hr.

Active tubular secretion contributes to the renal elimination of penciclovir. The plasma elimination half-life of penciclovir was 2.0±0.3 hours after intravenous administration of penciclovir to 48 healthy male volunteers and 2.3±0.4 hours after oral administration of 500 mg famciclovir to 124 healthy male volunteers. The half-life in 17 patients with herpes zoster was 2.8±1.0 hours and 2.7±1.0 hours after single and repeated doses, respectively.

Special Populations Geriatric Patients Based on cross study comparison, penciclovir AUC was 40% higher and penciclovir renal clearance was 22% lower in elderly subjects (n=18, age 65-79 years) as compared with younger subjects. Some of this difference may be due to differences in renal function between the 2 groups. No famciclovir dosage adjustment based on age is recommended unless renal function is impaired [see DOSAGE AND ADMINISTRATION, Use In Specific Populations]Patients With Renal Impairment In subjects with varying degrees of renal impairment, apparent plasma clearance, renal clearance, and the plasma-elimination rate constant of penciclovir decreased linearly with reductions in renal function, after both single and repeated dosing [see Use In Specific Populations ].

A dosage adjustment is recommended for patients with renal impairment [see DOSAGE AND ADMINISTRATION ].

Patients With Hepatic Impairment Mild or moderate hepatic impairment had no effect on the extent of availability (AUC) of penciclovir [see Use In Specific Populations ]. No dosage adjustment is recommended for patients with mild or moderate hepatic impairment. The effect of severe hepatic impairment on the pharmacokinetics of penciclovir has not been evaluated. HIV-Infected Patients Following oral administration of a single dose of 500 mg famciclovir to HIV-positive patients, the pharmacokinetic parameters of penciclovir were comparable to those observed in healthy subjects.

Gender The pharmacokinetics of penciclovir were evaluated in 18 healthy male and 18 healthy female volunteers after single-dose oral administration of 500 mg famciclovir. AUC of penciclovir was 9.3±1.9 mcg hr/m L and 11.1±2.1 mcg hr/m L in males and females, respectively. Penciclovir renal clearance was 28.5±8.9 L/hr and 21.8±4.3 L/hr, respectively. These differences were attributed to differences in renal function between the 2 groups.

No famciclovir dosage adjustment based on gender is recommended. Race A retrospective evaluation was performed to compare the pharmacokinetic parameters obtained in black and Caucasian subjects after single and repeat once-daily, twice-daily, or three times-daily administration of famciclovir 500 mg. Data from a study in healthy volunteers (single dose), a study in subjects with varying degrees of renal impairment (single and repeat dose) and a study in subjects with hepatic impairment (single dose) did not indicate any significant differences in the pharmacokinetics of penciclovir between black and Caucasian subjects.

Microbiology Mechanism Of Action Famciclovir is a prodrug of penciclovir, which has demonstrated inhibitory activity against herpes simplex virus types 1 (HSV-1) and 2 (HSV-2) and varicella zoster virus (VZV).

In cells infected with HSV-1, HSV-2 or VZV, the viral thymidine kinase phosphorylates penciclovir to a monophosphate form that, in turn, is converted by cellular kinases to the active form penciclovir triphosphate.

Biochemical studies demonstrate that penciclovir triphosphate inhibits HSV-2 DNA polymerase competitively with deoxyguanosine triphosphate. Consequently, herpes viral DNA synthesis and, therefore, replication are selectively inhibited. Penciclovir triphosphate has an intracellular half-life of 10 hours in HSV-1-, 20 hours in HSV-2-and 7 hours in VZV-infected cells grown in culture.

However, the clinical significance of the intracellular half-life is unknown. Antiviral Activity In cell culture studies, penciclovir is inhibitory to the following herpes viruses: HSV-1, HSV-2 and VZV. The antiviral activity of penciclovir against wild type strains grown on human foreskin fibroblasts was assessed with a plaque reduction assay and staining with crystal violet 3 days postinfection for HSV and 10 days postinfection for VZV.

The median EC 50 values of penciclovir against laboratory and clinical isolates of HSV-1, HSV-2, and VZV were 2 μM (range 1.2 to 2.4 μM, n=7), 2.6 μM (range 1.6 to 11 μM, n=6), and 34 μM (range 6.7 to 71 μM, n=6), respectively.

Resistance Penciclovir-resistant mutants of HSV and VZV can result from mutations in the viral thymidine kinase (TK) and DNA polymerase genes. Mutations in the viral TK gene may lead to complete loss of TK activity (TK negative), reduced levels of TK activity (TK partial), or alteration in the ability of viral TK to phosphorylate the drug without an equivalent loss in the ability to phosphorylate thymidine (TK altered).

The median EC 50 values observed in a plaque reduction assay with penciclovir resistant HSV-1, HSV-2, and VZV were 69 μM (range 14 to 115 μM, n=6), 46 μM (range 4 to >395 μM, n=9), and 92 μM (range 51 to 148 μM, n=4), respectively. The possibility of viral resistance to penciclovir should be considered in patients who fail to respond or experience recurrent viral shedding during therapy. Cross-Resistance Cross-resistance has been observed among HSV DNA polymerase inhibitors. The most commonly encountered acyclovir resistant mutants that are TK negative are also resistant to penciclovir.

Clinical Studies Herpes Labialis (Cold Sores)A randomized, double-blind, placebo-controlled trial was conducted in 701 immunocompetent adults with recurrent herpes labialis. Patients self-initiated therapy within 1 hour of first onset of signs or symptoms of a recurrent herpes labialis episode with FAMVIR 1500 mg as a single dose (n=227), FAMVIR 750 mg twice daily (n=220) or placebo (n=254) for 1 day.

The median time to healing among patients with non-aborted lesions (progressing beyond the papule stage) was 4.4 days in the FAMVIR 1500 mg single-dose group (n=152) as compared to 6.2 days in the placebo group (n=168).

The median difference in time to healing between the placebo and FAMVIR 1500 mg treated groups was 1.3 days (95% CI: 0.6–2.0). No differences in proportion of patients with aborted lesions (not progressing beyond the papule stage) were observed between patients receiving FAMVIR or placebo: 33% for FAMVIR 1500 mg single dose and 34% for placebo.

The median time to loss of pain and tenderness was 1.7 days in FAMVIR 1500 mg single dose-treated patients vs. 2.9 days in placebo-treated patients. Genital Herpes Recurrent Episodes A randomized, double-blind, placebo-controlled trial was conducted in 329 immunocompetent adults with recurrent genital herpes.

Patients self-initiated therapy within 6 hours of the first sign or symptom of a recurrent genital herpes episode with either FAMVIR 1000 mg twice daily (n=163) or placebo (n=166) for 1 day. The median time to healing among patients with non-aborted lesions (progressing beyond the papule stage) was 4.3 days in FAMVIR-treated patients (n=125) as compared to 6.1 days in placebo-treated patients (n=145).

The median difference in time to healing between the placebo and FAMVIR-treated groups was 1.2 days (95% CI: 0.5 to 2.0). Twenty-three percent of FAMVIR-treated patients had aborted lesions (no lesion development beyond erythema) vs. 13% in placebo-treated patients. The median time to loss of all symptoms (e.g., tingling, itching, burning, pain, or tenderness) was 3.3 days in FAMVIR-treated patients vs. 5.4 days in placebo-treated patients.

A randomized (2:1), double-blind, placebo-controlled trial was conducted in 304 immunocompetent black and African American adults with recurrent genital herpes.

Patients self-initiated therapy within 6 hours of the first sign or symptom of a recurrent genital herpes episode with either FAMVIR 1000 mg twice daily (n=206) or placebo (n=98) for 1 day. The median time to healing among patients with non-aborted lesions was 5.4 days in FAMVIR-treated patients (n=152) as compared to 4.8 days in placebo-treated patients (n=78). The median difference in time to healing between the placebo and FAMVIR-treated groups was -0.26 days (95% CI: -0.98 to 0.40). Suppressive Therapy Two randomized, double-blind, placebo-controlled, 12-month trials were conducted in 934 immunocompetent adults with a history of 6 or more recurrences of genital herpes episodes per year.

Comparisons included FAMVIR 125 mg three times daily, 250 mg twice daily, 250 mg three times daily, and placebo. At 12 months, 60% to 65% of patients were still receiving FAMVIR and 25% were receiving placebo treatment. Recurrence rates at 6 and 12 months in patients treated with the 250 mg twice daily dose are shown in Table 6.

Table 6 Recurrence Rates at 6 and 12 Months in Adults with Recurrent Genital Herpes on Suppressive Therapy Recurrence Rates at 6 Months Recurrence Rates at 12 Months Famvir 250 mg twice daily Placebo Famvir 250 mg twice daily Placebo (n=236) (n=233) (n=236) (n=233)Recurrence-free 39% 10% 29% 6%Recurrences † 47% 74% 53% 78%Lost to follow-up ‡ 14% 16% 17% 16%† Based on patient reported data; not necessarily confirmed by a physician.

‡ Patients recurrence-free at time of last contact prior to withdrawal. FAMVIR-treated patients had approximately 1/5 the median number of recurrences as compared to placebo-treated patients. Higher doses of FAMVIR were not associated with an increase in efficacy. Recurrent Orolabial Or Genital Herpes In HIV-Infected Patients A randomized, double-blind trial compared famciclovir 500 mg twice daily for 7 days (n=150) with oral acyclovir 400 mg 5 times daily for 7 days (n=143) in HIV-infected patients with recurrent orolabial or genital herpes treated within 48 hours of lesion onset.

Approximately 40% of patients had a CD4 + count below 200 cells/mm3, 54% of patients had anogenital lesions and 35% had orolabial lesions.

Famciclovir therapy was comparable to oral acyclovir in reducing new lesion formation and in time to complete healing. Herpes Zoster (Shingles)Two randomized, double-blind trials, 1 placebo-controlled and 1 active-controlled, were conducted in 964 immunocompetent adults with uncomplicated herpes zoster.

Treatment was initiated within 72 hours of first lesion appearance and was continued for 7 days. In the placebo-controlled trial, 419 patients were treated with either FAMVIR 500 mg three times daily (n=138), FAMVIR 750 mg three times daily (n=135) or placebo (n=146). The median time to full crusting was 5 days among FAMVIR 500 mg-treated patients as compared to 7 days in placebo-treated patients.

The times to full crusting, loss of vesicles, loss of ulcers, and loss of crusts were shorter for FAMVIR 500 mg-treated patients than for placebo-treated patients in the overall study population.

The effects of FAMVIR were greater when therapy was initiated within 48 hours of rash onset; it was also more profound in patients 50 years of age or older. Among the 65.2% of patients with at least 1 positive viral culture, FAMVIR treated patients had a shorter median duration of viral shedding than placebo-treated patients (1 day and 2 days, respectively). There were no overall differences in the duration of pain before rash healing between FAMVIR-and placebo-treated groups.

In addition, there was no difference in the incidence of pain after rash healing ( postherpetic neuralgia) between the treatment groups. In the 186 patients (44.4% of total study population) who developed postherpetic neuralgia, the median duration of postherpetic neuralgia was shorter in patients treated with FAMVIR 500 mg than in those treated with placebo (63 days and 119 days, respectively).

No additional efficacy was demonstrated with higher dose of FAMVIR. In the active-controlled trial, 545 patients were treated with 1 of 3 doses of FAMVIR three times daily or with acyclovir 800 mg five times daily.

Times to full lesion crusting and times to loss of acute pain were comparable for all groups and there were no statistically significant differences in the time to loss of postherpetic neuralgia between FAMVIR and acyclovir-treated groups. Sexually Transmitted Diseases (STDs) Slideshow Pictures Image Collection: Picture of Genital Warts (HPV)Take the Genital Herpes Quiz Medication Guide PATIENT INFORMATIONFAMVIR ® (Fam’-veer) (famciclovir) Tablets Read this Patient Information before you start taking FAMVIR and each time you get a refill. There may be new information. This information does not take the place of talking with your healthcare provider about your medical condition or treatment.

What is FAMVIR? Famvir is a prescription antiviral medicine used to:treat outbreaks of cold sores (fever blisters) in healthy adultstreat outbreaks of genital herpes in healthy adultsdecrease the number of outbreaks of genital herpes in healthy adultstreat outbreaks of herpes simplex lesions in or around the mouth, genitals, and anal area in people infected with HIVtreat shingles ( herpes zoster) in adults with normal immune system It is not known if FAMVIR is safe and effective in children younger than 18 years of age.

FAMVIR is not a cure for herpes. It is not known if FAMVIR can stop the spread of herpes to others.

If you are sexually active, you can pass herpes to your partner even if you are taking FAMVIR. Herpes can be transmitted even if you do not have active symptoms. You should continue to practice safer sex to lower the chances of spreading genital herpes to others.

Do not have sexual contact with your partner during an outbreak of genital herpes or if you have any symptoms of genital herpes. Use a condom made of latex or polyurethane when you have a sexual contact. Ask your healthcare provider for more information about safer sex practices. Who should not take FAMVIR? Do not take FAMVIR if you are allergic to any of its ingredients or to Denavir ® (penciclovir cream). See the end of this Patient Information leaflet for a complete list of ingredients in FAMVIR. What should I tell my healthcare provider before taking FAMVIR? Before you start taking FAMVIR, tell your healthcare provider if you:have kidney or liver problemshave a rare genetic problem with galactose intolerance, a severe lactase deficiency or you do not absorb glucose-galactose ( malabsorption)are pregnant or planning to become pregnant. It is not known if FAMVIR will harm your unborn baby Pregnancy Exposure Reporting: Novartis Pharmaceuticals Corporation collects pregnancy reports which are reported on a voluntary basis. In case of pregnancy, talk to your healthcare provider about reporting your pregnancyare breastfeeding or plan to breastfeed Tell your healthcare provider about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements. Especially tell your healthcare provider if you take:any other medicines and products you use to treat herpes outbreaksprobenecid (Probalan)Know the medicines you take. Keep a list of them with you to show to your healthcare provider and pharmacist every time you get a new medicine. How should I take FAMVIR? Take FAMVIR exactly as prescribed Your healthcare provider will tell you how many FAMVIR to take and when to take them. Your dose of FAMVIR and how often you take it may be different depending on your condition FAMVIR can be taken with or without food It is important for you to finish all of the medicine as prescribed, even if you begin to feel better Your symptoms may continue even after you finish all of your FAMVIR. This does not mean that you need more medicine, since you have already finished a full course of FAMVIR and it will continue to work in your body. Talk to your healthcare provider if you have any questions about your condition and your treatment What are the possible side effects of FAMVIR? The most common side effects of FAMVIR include:headachenausea Talk to your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of FAMVIR. Ask your healthcare provider or pharmacist for more information. Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA1088. How should I store FAMVIR? Store FAMVIR at room temperature between 59°F and 86°F (15°C to 30°C). Keep FAMVIR and all medicines out of reach from children. General information about FAMVIRMedicines are sometimes prescribed for purposes other than those listed in Patient Information leaflets. Do not use FAMVIR for a condition for which it was not prescribed. Do not give FAMVIR to other people, even if they have the same symptoms you have. It may harm them. This leaflet summarizes the most important information about FAMVIR. If you would like more information, talk with your healthcare provider. Your healthcare provider or pharmacist can give you information about FAMVIR that is written for health professionals. For more information, go to www. FAMVIR.com or call 1-888-669-6682. What are the ingredients in FAMVIR? Active ingredient: famciclovir Inactive ingredients: hydroxypropyl cellulose, hydroxypropyl methylcellulose, lactose, magnesium stearate, polyethylene glycols, sodium starch glycolate, and titanium dioxide Sexually Transmitted Diseases (STDs) Slideshow Pictures Image Collection: Picture of Genital Warts (HPV)Take the Genital Herpes Quiz Report Problems to the Food and Drug Administration You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA Med Watch website or call 1-800-FDA-1088. From Healthy Resources Infections More Likely with HIVSafe Sex Quiz: How Much Do You Know Are We Close to a Cure for Cancer? Featured Centers How Could You Live Better With Migraine? Not Being Defined by Your Cancer Track Cold & Flu in Your Area Health Solutions From Our Sponsors Frequent Constipation? Greater Food Accessibility "

Valtrex, (valacyclovir) famvir: If you have sever or frequently recurrent fever blisters it is vest to treat with oral antiviral for a week to lower the viral count. If recurrences are frequent a preventive dies of medication one to two pills a day will prevent recurrences.

Top 20 Doctor insights on: Antibiotics For Fever Blisters

"Top 20 Doctor insights on: Antibiotics For Fever Blisters Share Follow @Health Tap </> Embed Dr. Kayvon Javid1 doctor agreed:1 Could you tell me what are fever blisters? Herpes simplex 1 vir: Cold sores or fever blisters tend to develop when an individual has a fever but can also be triggered by sun exposure, emotional distress, intestinal illness and menstruation.

These blisters can recur in the same spot or in different locations. A sore or blister will typically ... Read more Dr. John Leander Po1,117 Doctors shared insights Antibiotic (Definition)An antibiotic is a medicine that slows, stops, or kills germs.

The germs are usually bacteria causing an infection in a person, so the person uses antibiotics to help his body get ... Read more Board Certified,Get help from a real doctor now Continue Dr. Klaus d Lessnau1 doctor agreed:2 What causes fever blisters on your chin? Usually: Herpes. Check with your doc about Acyclovir or Ganciclovir usage. ... Read more Dr. Morris Westfried4 doctors agreed:3 How to get rid of fever blisters?

Document severity and length of ... Read more Dr. Daniel Rubenstein2 doctors agreed:4 Is there a baby orajel for fever blisters? Fever blisters: Before applying anything check with your dentist or pediatrician. Your child may have a viral infection called herpetic stomatitis. Orajel is a topical anesthetic, but there are more effective treatments. ... Read more Dr. Hunter Handsfield5 Do L-lysine tablets work for fever blisters. Nope, no effect: D-Lysine has absolutely no benefit in people with either oral or genital herpes. Do not believe the many misleading claims you can find online and don't waste your money.

Acyclovir and related drugs effectively treat outbreaks (it only takes a single dose); if frequent, daily drug can ... Read more Board Certified,Get help from a specialist now Continue Dr. Heidi Fowler2 doctors agreed:6 What to eat to get rid of fever blisters fast?

Don't know foods. : Melissa officinalis or lemon balm (cream) expedites healing of cold sores. It can reduce healing time by half. Studies also show that regular use can help v recurrences. Brief supplementation with lysine 1, 000mg orally three times a day at the onset, can also hasten healing.

Your ... Read more Dr. Olayinka Adedayo3 doctors agreed:7 Is it possible that abreva cause fever blisters? No: Fever blisters is due to a viral infection called-herpes simplex-1. Abreva is an over the counter cream that may be helpful in treatment.

... Read more Dr. Richard Mizuguchi1 doctor agreed:8 Are cold sores and fever blisters the same thing? Yes: Cold sores and fever blisters are terms people use to describe a viral infection which usually affects the lips.

The most common cause is by the hsv1 virus. They can be treated with anti-viral medications. An episode typically lasts about 10-15 days. ... Read more Dr. Heidi Fowler2 doctors agreed:9 Is l-lysine effective in treating fever blisters? Yes: Brief supplementation w lysine 1, 000mg orally 3 times a day at onset, can hasten healing. Not a replacement for Valtrex though.

... Read more Dr. Heidi Fowler10 How can I most quickly get rid of fever blisters?3 options: Melissa officinalis or lemon balm (cream) has been shown in european studies to help expedite healing of cold sores.

It can reduce healing time by half. Studies also show that regular use can help v recurrences. Brief supplementation with lysine 1, 000mg orally three times a day at the ... Read more Dr. Michael Ein1 doctor agreed:11 What causes reocurring fever blisters on buttocks?

HSV 2: Herpes simplex virus type ii or genital herpes is the most likely cause. Frequent recurrences can be prevented by oral acyclovir, valacyclovir or famvir (famciclovir). Good luck. ... Read more Dr. Alan Ali1 doctor agreed:12 Can cold sores/ fever blisters have different looks?

Blisters: Yes, depending on what's inside them. Get help from a doctor now ›Dr. Ratna Dhingra1 doctor agreed:13 I would like help with my fever blisters (cold sores)? Zovirax (acyclovir): Cold sores are caused by herpes virus .they can be treated with oral anti-viral medications available by prescription from your doctor ... Read more Dr. Olayinka Adedayo1 doctor agreed:14 What method is there to get rid of these darn fever blisters?

None presently: The primary infection occured in early life. Repeated episodes follow virus living in nerve ganglion.

Will not respond to oral antivirals but topical antiviral may be used. ... Read more Dr. John Munshower3 doctors agreed:15 My 9 year old keeps getting fever blisters. Why? Are they contagious? Yes: Fever blisters/cold sores are most commonly caused by the hsv1 virus which is very common and found in most people. The virus is contagious and some people are simply more prone to getting the ""fever blisters"" than others.

There are some meds, including topicals that help decrease the duration ... Read more Dr. Martin Raff1 doctor agreed:16 If I have been getting fever blisters since I was a kid does that mean I could have the other type of virus also?

Vaginal herpes: Herpes in the genital tract can be either type 1 or type 2. Assuming you are already infected with type 1 with oral/labial lesions, that does not exclude the possibility you can also get type 2 genitally.

... Read more Dr. Clement Plaatjies17 I am having an issue with fever blisters right now. Will two one a day vitimans hurt me if I takr for a couple of days? Response: Hi Myra B. It depends on what’s in your vitamins. L-arginine has, albeit not with scientifically sound research, been shown to increase the incidence of fever blisters and l-lysine reduces it. Check your vita for these ingredients but remember, these weren’t proper statistically or scientifically ... Read more Dr. Michael Sparacino18 Are there other kinds of fever blisters that are not hsv?

I get one probably once a year and she said she doesn't have the same thing as me Yes: Several diffeent viruses are capable of producing blisters.

... Read more Dr. Hunter Handsfield19 Do L-lysine tablets work for fever blisters. I have used them and they worked for me and a few of my friends. You need to take up to 12 in a day but? Not herpes: In your message after my rearlier reply, you said your fever blisters clear within a day of taking lysine.

That means it wasn't a fever blister (oral herpes). Once a vesicle (blister) appears, no HSV outbreak can heal so fast. Effective treatment (e.g. valacyclovir) shortens average duration from ... Read more Dr. Arnold Malerman20 I have a blister on my hard palate on the left side.

It's not a fever blister. I've never had fever blisters. It's like a regular blister you would? Blister: May be draining abscess, mucocele, or other lesion. Please call your Dentist and make an appointment for an examination, differential diagnosis, and treatment. ... Read more Dr. Philip Miller1,737 Doctors shared insights Blistering (Definition)A blister is a collection of fluid under the epidermis. A blistering rash is one in which ... Read more Dr. Mark Diamond2,227 Doctors shared insights Fever (Definition)Fever = elevated body temperature (can be ... Read more "

Famciclovir (Famvir) is a drug used for the treatment of genital herpes, cold sores, shingles, and chickenpox. Side effects, drug interactions, warnings and precautions, and pregnancy information should be reviewed prior to taking this medication.

famciclovir

"Take the Shingles Quiz Shingles Slideshow Pictures Gallery of Skin Problems Pictures and Images Collection What is famciclovir, and how does it work (mechanism of action)? What brand names are available for famciclovir? Is famciclovir available as a generic drug? Do I need a prescription for famciclovir? What are the side effects of famciclovir? What is the dosage for famciclovir? Which drugs or supplements interact with famciclovir?

Is famciclovir safe to take if I'm pregnant or breastfeeding? What else should I know about famciclovir?

What is famciclovir, and how does it work (mechanism of action)? Famciclovir is an antiviral drug which is active against the Herpes viruses, including herpes simplex 1 and 2 ( cold sores and genital herpes) and varicella -zoster ( shingles and chickenpox ). It belongs to a class of drugs called nucleoside analogs that mimic one of the building blocks of DNA.

It stops the spread of herpes virus in the body by preventing the replication of viral DNA that is necessary for viruses to multiply.

Other drugs in the same class include acyclovir ( Zovirax) and valacyclovir ( Valtrex ). Famciclovir is actually a ""prodrug,"" that is, not active directly against viruses. Instead, famciclovir is converted to penciclovir in the body, and it is the penciclovir that is active against the viruses.

Famciclovir is active against the same viruses as acyclovir but has a longer duration of action. Therefore, it can be taken fewer times each day. Famciclovir does not cure or stop the spread of herpes infections. Famciclovir relieves pain, burning, itching, and tingling, and also heals and prevents sores associated with herpes infections.

Famciclovir was approved for use by the FDA in June 1994. What brand names are available for famciclovir? Famvir Is famciclovir available as a generic drug? GENERIC AVAILABLE: Yes Do I need a prescription for famciclovir? Yes What are the side effects of famciclovir? The most common side effects associated with the use of famciclovir are:headache,fatigue,nausea,vomiting,rash,diarrhea, andflatulence.

Other important side effects which are serious, but rare, includeserious allergic reactions,serious skin reactions,jaundice,abnormal tests of liver function, andreduced white blood cells ( neutropenia) or platelets ( thrombocytopenia ). Cases of kidney failure have been reported when higher than recommended doses of famciclovir were administered to patients with underlying kidney problems.

Quick Guide Shingles Rash Pictures, Symptoms, Vaccine Facts What is the dosage for famciclovir? Famciclovir may be taken with or without food. The recommended doses are: Recurrent genital herpes: 1,000 mg every 12 hours for one day. Recurrent cold sores: 1,500 mg as a single dose. Suppression of recurrent genital herpes: 250 mg twice daily. Shingles: 500 mg every 8 hours for 7 days.

HIV -infected patients ( cold sores or genital herpes): 500 mg twice daily for 7 days. Which drugs or supplements interact with famciclovir? Probenecid (Benemid) may reduce the kidney's removal of famciclovir leading to higher concentrations of famciclovir in the blood. This may lead to side effects from famciclovir. Take the Shingles Quiz Shingles Slideshow Pictures Gallery of Skin Problems Pictures and Images Collection Is famciclovir safe to take if I'm pregnant or breastfeeding?

Famciclovir has not been adequately studied in pregnant women. It is not known if famciclovir is excreted into human breast milk. Women may wish to consider an alternative to breastfeeding if famciclovir is taken. What else should I know about famciclovir? What preparations of famciclovir are available? Tablets: 125, 250, and 500 mg STORAGE: Famciclovir should be stored at room temperature, 15-30 C (59-86 F). From Tips to Better Manage Your Migraine Start Now Summary

Multimedia: Slideshows, Images & Quizzes Chickenpox Quiz: Test Your Medical IQHow is chickenpox related to shingles? Take the Chickenpox Quiz to assess your IQ of this itchy, blistering childhood skin... Shingles Quiz: Symptoms, Vaccine & Pictures Shingles falls within a well-known family of viruses that cause itching, burning, blisters, and pain.

Take the Shingles Quiz to... Bed Bugs Quiz: How to Get Rid of Bed Bugs That unexplained itching could be caused by bedbugs. Take the Bedbugs Quiz to learn the causes and symptoms of a bedbug... Genital Herpes Quiz: What is Genital Herpes?

What is genital herpes? Learn the causes, symptoms in men and women, and treatments for this common sexually transmitted skin... Picture of Shingles An acute infection caused by the herpes zoster virus, the same virus as causes chickenpox.

See a picture of Shingles and learn... Picture of Herpes Zoster Also called shingles, zona, and zoster. The culprit is the varicella-zoster virus. Primary infection with this virus causes... Picture of Herpes Simplex Virus Type 1A herpes virus that causes cold sores and fever blisters in and around the mouth. See a picture of Herpes Simplex Virus Type 1... Picture of Herpes Simplex Virus Type 2A herpes virus that causes genital herpes, which is characterized by sores in the genital area.

See a picture of Herpes Simplex... Picture of Varicella-Zoster Virus Infection (Face)Multiple, very pruritic, erythematous papules, vesicles (“dewdrops on a rose petal”), and crusted papules on erythematous,... Picture of Varicella (Chickenpox) Virus A highly infectious viral disease, known familiarly as chickenpox. See a picture of the Varicella (Chicken Pox) Virus and learn... Picture of Varicella Chicken Pox Varicella Chickenpox is caused by a virus of the herpes group.

The disease is highly contagious and is spread by droplet or... Picture of Herpetic Whitlow Painful grouped red-blue vesicles on the middle finger of a child.

See a picture of Herpetic Whitlow and learn more about the... Picture of Varicella-Zoster Virus Infection on Chest Wall Typical grouped vesicles and pustules with erythema and edema of three contiguous thoracic dermatomes on the posterior chest... Picture of Varicella-Zoster Virus Infection Close-Up Grouped and confluent vesicles surrounding erythema on the chest wall.

See a Varicella-Zoster Virus Infection: Close-Up and learn... Cold Sores Causes, Remedies, & Diagnosis How to get rid of cold sores? First learn about the herpes virus and how it causes cold sores. When are cold sores contagious?...

Related Disease Conditions Chickenpox (Varicella)Chickenpox (chicken pox) is a contagious childhood disease caused by the varicella-zoster virus. Symptoms have an incubation... Shingles Shingles, or herpes zoster, is a painful rash caused by the varicella zoster virus. Other shingles symptoms include headache,... Sexually Transmitted Diseases in Women (STD)Sexually transmitted diseases, or STDs, are infections that are transmitted during any type of sexual exposure, including... Ramsay Hunt Syndrome Ramsay Hunt syndrome is an infection of a facial nerve that causes a red painful rash with blisters and facial paralysis.

Other... Genital Herpes in Women (Symptoms, Signs, Treatment)Genital herpes is a sexually transmitted disease (STD) caused by the herpes simplex virus (HSV). Symptoms of genital herpes... Cold Sores (Nongenital Herpes Simplex Infections)Herpes simplex infections are common and when they appear around the mouth and lips, people often refer to them as ""cold sores""... STDs in Men Sexually transmitted diseases (STDs) are infections transmitted during sexual contact.

They may be caused by viruses, bacteria,... Itch (Itching or Pruritus)Itching can be a common problem. Itches can be localized or generalized. There are many causes of itching to include: infection... Sexually Transmitted Diseases and Pregnancy (STDs)When you are pregnant, many sexually transmitted diseases (STDs) can be especially harmful to you and your baby. These STDs... Pityriasis Rosea Pityriasis rosea is a rash that begins with a large pink patch with well-defined scaly borders on the back, chest, or neck.

In... Shingles and Pregnancy Becoming infected with chickenpox during pregnancy could cause birth defects in your unborn child.

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Pimples are caused by... Treatment & Diagnosis Symptoms & Signs FAQs & Doctor's Views Doctor: Checklist to Take To Your Doctor's Appointment Herpes Shingles Ocular Herpes Medications & Supplements Medications FDA Drug Labels on Rx List.comacyclovir, Zovirax Valtrex (valacyclovir)Drugs: What You Should Know About Your Drugs Drug Interactions Prevention & Wellness Health News Health Features Experimental Gel Could Prevent Genital Herpes Infection Experimental Drug Shows Promise for Genital Herpes Treatment Herpes Drugs Don't Stop Herpes Spread Gene May Be Linked to Frequent Cold Sores Herpes Drugs May Be Safe in Early Pregnancy Take the Shingles Quiz Shingles Slideshow Pictures Gallery of Skin Problems Pictures and Images Collection Daily Health News Hot Chili Pepper Hospitalizes Man Woman Claims Fertility Doctor As Her Father Mom's Marijuana in Breast Milk Toddlers, Opioids Victims Focus Shift in Alzheimer's Research More Health News »Trending on Medicine Net Autism Spectrum Disorder (ASD)E. Coli Hepatitis ABurning Urination (Dysuria)Scabies From Healthy Resources Shingles and Other Common Skin Problems How to Treat Cold Sores7 Ways to Curb Your Psoriasis Flare-Ups Featured Centers How Could You Live Better With Migraine?

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Visit the FDA Med Watch website or call 1-800-FDA-1088. See more info: famciclovir on Rx List References Related Article Shingles Quiz: Symptoms, Vaccine & Pictures What is shingles? Is shingles contagious? What does shingles look like? Take the Shingles (Herpes Zoster) Quiz featuring pictures, quick facts, symptoms, treatments, and causes of this itchy, painful rash. Read more: Shingles Quiz: Symptoms, Vaccine & Pictures Complete List Top famciclovir Related Articles Bed Bugs Quiz That unexplained itching could be caused by bedbugs.

Take the Bedbugs Quiz to learn the causes and symptoms of a bedbug infestation. Chickenpox (Varicella)Chickenpox (chicken pox) is a contagious childhood disease caused by the varicella-zoster virus. Symptoms have an incubation period of 14 to 16 days and include a couple days of mild fever, weakness, and red, raised rash that progresses to blisters that eventually burst and crust over.

Complications include bacterial infection of the open sores, scarring, encephalitis, nerve palsies, and Reye's syndrome. Cold Sores Slideshow How to get rid of cold sores? First learn about the herpes virus and how it causes cold sores. When are cold sores contagious? Get information on triggers that can cause a flare up in cold sore symptoms.

Genital Herpes in Women Overview Genital herpes is a sexually transmitted disease (STD) caused by the herpes simplex virus (HSV). Symptoms of genital herpes include painful blisters and often fever, body aches, and swollen lymph nodes for first time infection.

Genital herpes is diagnosed with lab tests to test for the presence of the virus. Treatment for genital herpes includes antiviral medications to shorten the duration of the outbreak or reduce the risk of future outbreaks. There is no cure for genital herpes. Condoms may help prevent the spread of genital herpes. Genital Herpes Quiz What is genital herpes? Learn the causes, symptoms in men and women, and treatments for this common sexually transmitted skin disease.

Herpes Simplex Infections (Non-Genital)Herpes simplex infections are common and when they appear around the mouth and lips, people often refer to them as ""cold sores"" and ""fever blisters."" Canker sores are different than cold sores. Air droplets can spread the virus, as can direct contact with the fluid from the blisters.

Cold sore treatment include over-the-counter medication, as well as prescription medications. Itch Itching can be a common problem. Itches can be localized or generalized. There are many causes of itching to include: infection (jock itch, vaginal itch), disease (hyperthyroidism, liver or kidney), reactions to drugs, and skin infestations (pubic or body lice).

Treatment for itching varies depending on the cause of the itch. Pityriasis Rosea Pityriasis rosea is a rash that begins with a large pink patch with well-defined scaly borders on the back, chest, or neck. In one to two weeks, the person will develop many smaller pink patches on his or her trunk, arms, and legs.

Symptoms include mild itching and possible sore throat, fatigue, nausea, aching, and decreased appetite. Pityriasis rosea typically resolves on its own and symptoms and signs may be treated with topical steroid creams and oral antihistamines.

Ramsay Hunt Syndrome Ramsay Hunt syndrome is an infection of a facial nerve that causes a red painful rash with blisters and facial paralysis. Other symptoms of Ramsay Hunt syndrome may include:ear pain, hearing loss, dizziness (or vertigo), dry eye, and changes in taste sensation.

The herpes zoster virus causes the infection. The infection is treated with:antiviral agents, steroids, and pain medications. Sexually Transmitted Diseases (STDs In Women)Sexually transmitted diseases, or STDs, are infections that are transmitted during any type of sexual exposure, including intercourse (vaginal or anal), oral sex, and the sharing of sexual devices, such as vibrators.

Women can contract all of the STDs, but may have no symptoms, or have different symptoms than men do.

Common STDs in women are: Gonorrhea Chlamydia Zika virus Genital herpes Hepatitis B Hepatitis C Pubic lice Scabies Genital warts Treatment for STDs depends upon the type. Sexually Transmitted Diseases and Pregnancy (STDs)When you are pregnant, many sexually transmitted diseases (STDs) can be especially harmful to you and your baby. These STDs include herpes, HIV/AIDS, genital warts (HPV), hepatitis B, chlamydia, syphilis, gonorrhea, and trichomoniasis. Symptoms include bumps, sores, warts, swelling, itching, or redness in the genital region. Treatment of STDs while pregnant depends on how far along you are in the pregnancy and the progression of the infection.

Shingles (Herpes Zoster)Shingles, or herpes zoster, is a painful rash caused by the varicella zoster virus.

Other shingles symptoms include headache, fever, nausea, and body aches. Treatment focuses on pain management and shortening the duration of the illness with antiviral medications. Take the Shingles Quiz Shingles falls within a well-known family of viruses that cause itching, burning, blisters, and pain. Take the Shingles Quiz to get the facts, causes, symptoms, and treatments for this itchy, painful condition. Shingles Pictures An acute infection caused by the herpes zoster virus, the same virus as causes chickenpox.

See a picture of Shingles and learn more about the health topic. STDs in Men Overview Sexually transmitted diseases (STDs) are infections transmitted during sexual contact. They may be caused by viruses, bacteria, or parasites. STDs in men cause no symptoms or symptoms likegenital burning, itching, sores, rashes, or discharge.

Common infections that are sexually transmitted in men include gonorrhea, chlamydia, syphilis, hepatitis C and B, genital warts, human papillomavirus (HPV), and genital herpes. Some STDs in men are treatable while others are not. STDs are diagnosed with tests that identify proteins or genetic material of the organisms causing the infection.

The prognosis of an STD depends on whether the infection is treatable or not. Use of latex condoms can help reduce the risk of contracting an STD but it does not eliminate the risk entirely.

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The treatment dose for famvir is 1000 mg twice a day for one day for genital herpes, and for cold sores, take a single dose of three 500-mg tablets at the first sign or symptom of an outbreak (within 1 hour). After that, you could go right into the suppression dose, which is 250 mg twice a day.

Acyclovir dosage cold sores

"Acyclovir dosage cold sores Common Questions and Answers about Acyclovir dosage cold soreszovirax At first I was getting cold sores about every 4 to 6 weeks. I then started taking 500 mg of Valtrex daily for suppression therapy. This seemed to reduce the frequency of my outbreaks to about once every 2 to 3 months. To save money, my insurance switched me to acyclovir (400 mg twice a day) with similar results as the Valtrex.

Then starting about 3 months ago, I began to have outbreaks every two weeks even with the suppression therapy. Read More I have experienced non-stop severe cold sores for almost three months. I know how I got infected, and know I've never had them before.

They cover the outer half of both lips, top and bottom). I've tried acyclovir and generic valtrex, with no relief. Not even a two hour break. Still taking generic valtrex (1 gram twice a day). I am taking Thompson's lip relief (lysine, vit c, zinc, bioflavanoids) and an immune support (andrographis,olive leaf, echinacea), and have been for a few weeks.

Read More I understand it reduces the frequency of outbreaks and of asymptomatic shedding to some degree. I have had cold sores (i.e., HSV-1) as long as I remember (certainly before sexual activity), and I understand this also provides some protection.

Assume I am uninfected. Suppose she starts using daily suppressive treatment with acyclovir, and we did not have unprotected sex during symptomatic outbreaks.

Read More As I had mentioned, my past has included what i know now was coldsores (3 outbreaks in 5 years) twice when i cut my lip, one after i had very chapped lips on a beach holiday. I noticed legions on my penis shaft 10 days after oral sex (Nov 2nd). this girl laster tested positive got HSV 2 and had a yeast infection.

I went to my urologist who sent me to a ex army Dermatoligist and veneralogist- he said it was classic herpes. Read More I understand that Valtrex its just 1 pill - - Acyclovir is x2 and possiblities of missing a dosage is more likely however is Acyclovir more affective? Read More Good morning, Big event coming up and I occasionally get cold sores. My question is, can I take Valacyclovir a few days in advance as sort of a preventative measure?

If so how many milligrams would you recommend? Finally, at first sign of an outbreak what is recommended dosage of Valacyclvir?

Thanks so much. Read Morealso have you ever been tested for herpes or had cold sores before? Read More Also, there are 2 spots above my clitoris (where the labia split) that look like little papercuts that burn and itch. On my acyclovir rx label it says to increase the dosage to 2 tabs three times daily for 2 days during an outbreak and Ive done that but it did not help the situation.

I would normally go to the dr. immediately but they will be closed until next monday after the holiday.

I really dont know if this is a herpes outbreak (if so then why didnt the meds work? Read More Hello all, I am wondering if anyone has any insight as to why I am constantly getting cold sores even tho I am on antivirals (acycolvir).

I have seen a health care provider and all they tell me is to wait it out. I have had cold sores in the past 2 a year but for the last 7 months I have had constant outbreaks.

I am wondering if there is any suggestion out there as to what I am doing wrong? Read More I'm taking Acyclovir whenever another one comes up but it really doesn't seem to be helping.

I'm so sick and tired of this. WHY???? My BF doesn't feel anything!!!! Why do some people have it really bad and others don't feel a thing???? I take vitamins, eat healthy, use to excercise before these sores started controlling my life.... Read More What sort of testing have you been thru so far?

This is oral herpes/cold sores you are refering to? Read More I've been mildly to severely fatigued during the past week and the burning persisted for a few days without visible sores so I visited urgent care and was diagnosed with possible cold sores on the crevices of my lips (group of tiny clear painless bumps) and a possible bacterial infection (Folliculitis) on my pelvic region.

I was prescribed with Acyclovir and have been taking the recommended dosage for a couple days. Read More How often are you getting cold sores lately? Are they typical cold sores on the outer lip area or inside your mouth? Read Moreif so isn't the incubation period of cold sores like 10-14 days?

I have had nothing resembling cold sores like pain, discomfort or anything and im comin up on 10 days post exposure. could this be because I'm immune since i have gotten canker sores since i was early teenager. again thanks for all the input, i think im looking for things that aren't there i'm kind of a paranoid person in general.

Read More If you had a new hsv1 infection you would know it. One more thing. If you ever get cold sores on your lip then you would be immune to getting hsv1 of the genitals.

Read More My boyfriend is in the process of getting a blood test for herpes but we suspect that he does not have any infection as he has no history of cold sores /lesions. I am currently taking acyclovir to treat this outbreak and I am on my third day of treatment at 400 mg, three times daily. Here are my questions: 1. Is my dosage of acyclovir enough? I still feel a little itchy and noticed I still have bumps in the shower.

How long will it take to clear up? 2. Read More I just spoke to my Dr at PP again today and she sounded in a rush, she said to just refill my Acyclovir and continue the dosage as the same and that would be my suppressive therapy.

I'm worried about the chance of my body building up a tolerance too fast. What is the likelihood of this? And also, I have started taking lysine. Am I on the right track? I feel a little lost and scared here.

Read More I have taken Acyclovir and Valtrex in the past and it never seemed to make much of a difference.

I have spent thousands like all of you on ""natural remedies"" I thought I was on to something with Red Marine Algae several years back so for the past two months I have taken that, Lysine, Oil of Oregano, Echinacea, colliadol silver,liquid oxygen, etc.

Apple Cider vinegar dries the sore right up but the next day a new crop of them appear. They just seem to keep regenerating. Read More I hope I am writing this in the correct place! Grace, I cannot believe I was misinformed about the dosage of my acyclovir, I am a little angry about it actually.

Even the lable on the prescription bottle is wrong! I will start taking the 800mg a day. My new partner is negative for all STDs.

I have an appointment to get screened for all STD's just to be sure nothing else is going on other than my HSV 1. Read More However, right after I took the PCR test last Friday (two weeks after my initial symptoms broke out), I started getting the same aching, burning sensation yet with no symptoms on the right side of my vaginal lip in the exact same location.

I started taking three 400 mg acyclovir pills last Friday (the dosage I take when I get a cold sore), and by about 48 hours later, all symptoms had gone away everywhere and my vaginal region felt ""normal"" for the first time in weeks.

Read More I had no history of these viruses prior to coming into contact with this person. About 3 weeks later I broke out with several cold sores in my mouth ( I was still taking Zovirax and they went away in a few days) . In November of 2007 I went off the meds to see how I would do. On the weekend of the Nov 10 I felt very sick and weak and felt like I had the flu.

I went back on the meds. Read More I've experienced cold sores for the majority of my life. Recently I've been exposed to genital hsv1 because the girl didn't tell me she was having an active outbreak. I'm wondering if this would constitute as a new primary infection? I'm now experiencing hsv ear lesions as well, everything has been confirmed as hsv1.

I'm curious how I'm now experiencing hsv in my ear if I've had a long standing infection and what type of precautions I need to take going forward? Read More I'm sorry, genital herpes (as well as cold sores) are lifelong infections. However, some people experience a decrease in herpes outbreaks over time.

I think you may be thinking of HPV, not HSV. HPV clears within 6 months to a couple years. What is your daily acyclovir dosage? Read More I haven't let my lover give me oral because I think it's not safe even with acyclovir. Can hsv2 be passed on in this way? What would happen? Would he get cold sores? Thank you!Read More Hi Catin, Thanks for the reply on my HSV questions.

You asked how my diagnosis of the beltway blisters was. It was a visual with a doctor, no swabs/blood tests but we are 100% certain it's the herpster. I assumed it was 2 because I already have 1 orally and have for 30 years; but I haven't had a cold sore in 20. Is it possible that I've also got 1 down there? It's my understanding that after as many years as I've had 1 that it's not.

Read More, sunburn, local surgery) and other illnesses, hence the names fever blisters and cold sores. No triggers have ever been proved for genital herpes due to HSV-2. To my knowledge there are no good data either way for genital HSV-1, however.

Read More I had an outbreak genitally and after that had nearly continuous cold sores on my mouth and nose.

It sucks! I was treated with acyclovir, 200 mg 4 times a day and that didn't really work. I am now taking 500 mg Valtrex once a day. This is working somewhat well, but I am having some breakthrough symptoms around the time of ovulation.

I am extremely worried that my herpes is becoming resistant. Here are my questions: 1. Can I increase my Valtrex dosage or try another drug (Famvir? Read More A couple of years back I performed oral sex on a girl that I later found out had HSV 2 genital herpes, I have had 2 cold sores after our encounter but haven't had any cold sores for about 2 years. Since I only performed oral sex on her I have had no genital issues. Fast forward to the present, I have found someone who I want to carry on a relationship with and we both decided to get tested for all STDs to make sure we are clean for each other. Read More

The treatment dose for famvir is 1000 mg twice a day for one day for genital herpes, and for cold sores, take a single dose of three 500-mg tablets at the first sign or symptom of an outbreak (within 1 hour). After that, you could go right into the suppression dose, which is 250 mg twice a day.

That said, I wonder if this is all herpes. You wouldn't get herpes on your torso. Read More We were being as safe as possible, using condoms, etc., and I don't have obvious genital symptoms.

I had cold sores on my mouth as a child sometimes in the winter (likely HSV1), but they haven't returned since age 13 or so. This discussion is related to Painful small white spots on the tongue. Read More Recommended "

They can lower the amount of healing time when you take them at the first sign of a cold sore -- like tingly, red, or itchy skin. You’ll start acyclovir before cold sores fully flare and take it five times a day for 5 days, or you can take valacyclovir (Valtrex) at the first sign of a cold sore and then 12 hours later. Famciclovir (Famvir) can be given as a single dose of medicine.

Treating & Preventing Cold Sores

Treating & Preventing Cold Sores1 / 17The Basics Cold sores -- you might hear them called fever blisters -- are proof that life can be unfair. Some people get them, others don’t. If you get them, don't worry. There are ways to treat and prevent them.

Swipe to advance1 / 17Your Cold Isn't to Blame Despite the name, that isn’t what causes them. The herpes simplex virus type 1 (HSV-1) is most often the cause. You get it from contact with an infected person’s skin or body fluids. The virus damages your skin as it reproduces.

That leaves behind weepy sores that last about a week. Between outbreaks, HSV-1 hides inside nerve cells, so it’s never completely cured. Swipe to advance1 / 17Why Doesn't Everyone Get Them? About two-thirds of us have been infected with the HSV-1 virus.

It usually comes via well-meaning kisses from relatives or romantic partners. So why do only an unlucky few get cold sores? The answer may be in your genes. Most of the people who get cold sores share genes that may relate to how HSV-1 acts in your body. This could be what causes outbreaks. Swipe to advance1 / 17What Are Your Triggers? HSV-1 lives in your nerves.

It’s pretty quiet most of the time, but you may have triggers that bring it out of hiding and cause cold sores. They can range from sunlight or a fever to stress and getting your period. Some people get cold sores twice a year or less. For others, it’s a monthly ordeal. Swipe to advance1 / 17Canker Sores Aren't the Same Cold sores usually appear on your lip. Canker sores affect the inside of your mouth. They don’t involve the herpes virus and aren’t contagious.

No one knows what causes them. Cold sores generally signal their arrival with a warning period of red, irritated skin. Blisters form, burst, and then crust over before they heal. Swipe to advance1 / 17When Are You Contagious?

From the time your skin turns itchy or red, the virus is likely present and you can spread it. You’re most contagious when blisters show up and just after they burst.

Once your skin is completely healed and looks normal again, you can’t spread it that way. But you can still pass the virus through your saliva at any time, even when you don't have a cold sore. Swipe to advance1 / 17How Does the Virus Spread? Through body fluids. It’s usually present on an infected person’s lip, even if there’s no obvious sore.

Kisses are the main method. Because the virus often lives in saliva, you can also spread it if you share kitchen utensils or drinking glasses. Oral sex sometimes leads to infection of your partner's genitals. Swipe to advance1 / 17Can You Stop the Spread? Yes. Use caution while you have a sore. Don’t kiss, and don't share toothbrushes, silverware, or glasses. Skip oral sex. That will reduce most of the spread of HSV-1, although you may not be able to control the spread completely. Swipe to advance1 / 17How to Ease Your Pain While the first outbreak can last up to 2 weeks, the ones after that may not be longer than a week.

There’s no cure for cold sores, but some over-the-counter creams and gels can ease symptoms like burning and pain.

You can also try hot or cold compresses. Swipe to advance1 / 17Antiviral Creams Can Help They often shorten the time it takes a cold sore to heal. But they work best if you put them on at the very first sign of an outbreak. Docosanol cream is available over the counter. Acyclovir (Zovirax) cream and penciclovir (Denavir) cream are available by prescription. Swipe to advance1 / 17Prescription Meds Are Available

So can acyclovir buccal (Sitavig), but instead of swallowing it you place against your gums and it releases the medicine as it dissolves. Swipe to advance1 / 17How Do You Know It's a Cold Sore? What about a cold sore that isn’t on your lip? They aren’t as common, but they can pop up anywhere on your face, like your cheek, chin, or nose. Most people’s cold sores reappear in the same area each time.

Swipe to advance1 / 17Can It Spread to Your Body? Yes, but it’s rare. It can happen if you touch a cold sore, then touch an area of broken skin or a mucous membrane (that’s the moist, protective lining found in places where your body opens to the outside -- mouth, nose, genitals).

That can lead to a herpes skin infection. To prevent this, wash your hands and don’t touch the cold sore. Swipe to advance1 / 17Where Else Might It Strike? Your eyes: This is called ocular herpes, and it most often affects the cornea.

It’s the leading infectious cause of corneal blindness in the U. S., so get treatment as soon as possible. Herpetic whitlow is a painful condition that affects your fingers. Kids often get it when they have a cold sore and suck their fingers or thumb.

Swipe to advance1 / 17How Do You Prevent Outbreaks? It’s tough to hold them off entirely, but there are things you can do to help keep them at bay.

Learn what your triggers are and avoid them. Stay out of the sun, or use sunscreen and UV-blocking lip balm. Figure out what works to manage your stress. Keep your immune system healthy with plenty of sleep and daily exercise. Swipe to advance1 / 17When Should You See a Doctor? Make an appointment if: You have a weakened immune system.

The cold sores don't heal within 2 weeks. Your symptoms are severe. Your eyes are irritated. You have severe or frequent cold sore outbreaks. Swipe to advance Up Next Next Slideshow Title Skip Ad1 / 17 Skip Ad Sources | Medically Reviewed on 12/15/2017This tool does not provide medical advice. See additional information.

There are several effective treatments for shingles. Drugs that fight viruses (antivirals), such as acyclovir (Zovirax), valacyclovir (Valtrex), or famciclovir (Famvir), can reduce the severity and duration of the rash if started early (within 72 hours of the appearance of the rash).

Shingles

"Shingles Facts What Are Risk Factors for Shingles? What Are Causes of Shingles? What Are Symptoms and Signsof Shingles?

When Should Someone Seek Medical Care for Shingles? How Do Health-Care Professionals Diagnose Shingles? Are There Shingles Home Remedies? What Medications Treat Shingles? Is Follow-up Needed After Treatment of Shingles? Is Shingles Contagious? How Long Does Shingles Last? Is Shingles Prevention Possible? Is There a Shingles Vaccine? What Specialists Treat Shingles? What Is the Prognosis for Shingles? What Are Possible Shingles Complications? Shingles Facts

Shingles (also termed herpes zoster or zoster) is a disease caused by reactivation of a previous infection with the herpes zoster virus (also named varicella-zoster virus, VZV, HHV-3, or chickenpox virus) that results in a painful localized skin rash, usually with blisters (fluid-filled sacs) on top of reddish skin.

Herpes zoster viruses do not cause the sexually transmitted disease genital herpes. That disease is caused by another virus named herpes genitalis (also termed herpes simplex virus, type 2 or HSV-2).

The chickenpox virus (varicella-zoster, VZV) may remain in a dormant state in the body after an individual has chickenpox, usually in the roots of nerves that control sensation. In about one out of five people previously infected with chickenpox, the virus ""wakes up,"" or reactivates, often many years or decades after a childhood chickenpox infection. When the virus is reactivated and causes shingles, the resulting virus is usually referred to as herpes zoster virus. Researchers do not know what causes this reactivation. What is known is that after reactivation, the virus travels along a sensory nerve into the skin and causes shingles.

The term shingles is derived from the Latin and French words for belt or girdle, reflecting the distribution of the rash in usually a single broad band. This band is only on one side of the body in the large majority of people and represents a dermatome -- the area that a single sensory nerve supplies in the skin.

The painful area may occupy part or all of the dermatome (see figure 1 below). What Are Risk Factors for Shingles? The majority of people who get shingles are over the age of 60; it infrequently occurs in younger people and children. Investigators estimate that about 1 million cases of shingles occur per year in the U. S.

Risk factors for shingles are common, and the majority of people have at least one or more risk factors. For example, anyone who has had the chickenpox infection or chickenpox vaccine (live attenuated virus) may carry the herpes zoster virus that causes shingles.

Older people (over 50 years of age), those with cancer, HIV, or organ transplant, or people who have a decreased ability to fight off infection due to stress or immune deficiency have a greater chance of getting shingles.

However, the majority of people with shingles or risk factors for shingles are relatively healthy. Most people do not need special tests to be done to see if their immune system is strong and functioning normally.

""What does shingles look like?"" To answer the question, the following figure shows the lesions forming a band across the patient's left abdomen. Figure 1: Picture of shingles in a child with leukemia showing a characteristic band of lesions; SOURCE: CDC. Take the Shingles Quiz Shingles Slideshow Pictures Pictures of Shingles What Are Causes of Shingles?

Herpes zoster virus causes shingles. No one knows for sure what causes the chickenpox virus to become reactivated to cause shingles. Some investigators suggest that the following conditions may participate in virus reactivation, since they have been associated with a higher incidence of shingles.

This is a list of only some of the major conditions that may trigger reactivation but have as yet not been proven to do so: Stress Fatigue A weakened immune system (This may be age-related, disease-related, or a drug-related decrease in ability to keep the chickenpox virus in an inactive state. )Cancer Radiation treatments Injury of the skin where the rash occurs HIV/AIDSShingles Treatment & Complications

ion Common Questions and Answers about Famvir no prescriptionfamvir My doctor gave me a prescription for famvir, which I was able to start taking approx 30 hours after being infected...already had a significant patch of little white dots. It was the first one had every had (I know because I became very ill with a fever and night sweats etc a couple of days later).

Famvir no prescription

"Famvir no prescript

The white dots became several white patches from one corner of my mouth to the other mostly on the part of the lip that isn't really visible when my mouth is closed. Read More

Hello. I have recurrent cold sores and have a Famvir prescription for this. Two weeks ago, I felt and saw redness, lumpiness and then a whitish sore that I associate with cold sores and hurriedly bolted down 1500mg of Famvir. But the sore/lesion seems to have been on the inside of my lip (the moist inner mouth), and not on my skin.

Stupidly I didn't think of this til later. I think, in my panic, I just went for the meds as the easy solution without thinking. Read More Hello. I have recurrent cold sores and have a Famvir prescription for this. Two weeks ago, I felt and saw redness, lumpiness and then a whitish sore that I associate with cold sores and hurriedly bolted down 1500mg of Famvir.

But the sore/lesion seems to have been on the inside of my lip (the moist inner mouth), and not on my skin. Stupidly I didn't think of this til later. I think, in my panic, I just went for the meds as the easy solution without thinking.

Read More All non-controlled prescription products Eli Lilly and Company (800) 545-6962 Products include: Most all Lilly prescription products and insulins.

Fisons Pharmaceuticals Gastrocon Patient Assistance Program P. O. Box 1766 Rochester, NY 14603-1766 Products include: Gastrocrom capsules Fujisawa (800) 477-6472 Products include: Prograf (708) 317-8636 Products include: Nebu Pent Genentech, Inc. Read More There are no over the counter antiviral meds for herpes.

You would need a prescription for either Valtrex, Acyclovir or Famvir. Read More Ok, so I've been putting up with on again, off again itching for months on my labia, near my vaginal opening. Never ""diagnosed"" with HPV but I did get rid of a suspected wart this past year. Can you have a bacterial infection without discharge?

It drives me CRAZY sometimes, the only thing that calms it is gold bond ointment, which is minty and refreshing but I'd like no itch.

No ""rash"" that I can see, unless I give in and scratch. Read More These are Valtrex/valacyclovir, Famvir /famciclovir, and acyclovir. They require a doctor's prescription . There are also several topicals that you can get over the counter.

Some of these are Abreva, Releev, and Dermoplast. In addition some people use natural remedies such as honey, which has been found to have antiviral properties. However, these have not been formulated, and have had no clinical trials, specifically to treat HSV. Read More I was recently diagnosed with HSV-2. My dr put me on Famvir 250mg... he said to take 1 pill per day and if I have an active outbreak, to take 4 pills twice daily for 2 days. My questions are as follows: 1. Is 250mg of Famvir once a day enough to prevent my outbreaks? How long can I safely take Famvir? It seems studies Ive read say not to take it past one year... what are you supposed to do after a year?

2. Is Famvir better than Valtrex? 3. Read More Famvir kills herpes and has no side effects. If the sore is worse, it may be bacterial or som thing other than viral. Check wth your doctor first thing. Dr. Read Morezovirax ointment isn't helpful for herpes recurrences. no need to refill that prescription that's for sure. What herpes testing have you had done so far?

Read More OK what do you think about this. I asked for a prescription on famvir and if he could give me more capsule count and he wouldnt work with me at all. Instead after this he wrote me a prescription for 10 capsules 250 mg which was less than the last time which he game me 12 capsules 500mg. So shouldnt it have worked opposite if i asked for more this time? Shouldnt i have atleast been giving a little more?

what kind of prescriptions do you guys get? Read More Well valtrex is generic now everywhere so it shouldn't be a money issue for most folks if they have decent prescription coverage with their insurance.

Acyclovir is still way cheaper but if you have insurance coverage that makes generics low cost, valtrex is, as of this month, going to be WAY cheaper for you now :) the technicality to the answer to your question is this - only valtrex has been studied for reduction in transmission to a partner.

Read More You can use acyclovir, valtrex or famvir for this. Just keep in mind that the antivirals work best when taken at the very first sign of a potential ob so if you start feeling that tell tale tingle/itch or whatever your prodrome is ( if you have one ) start the meds then. No need to wait until you have a full blown ob - the sooner you can start the meds the faster they work. Some folks can even head off a full blown ob if they start medication early enough. Read Mor

elooks like might be herpes, prescribed Famvir = no changes after completion of prescription. -10/10/12=gyn appt, swab culture for herpes, pap=both negative -10/14/12 Herpes !Read Morethe topicals for cold sores don't do much at all. give the doc a call and ask for a prescription for herpes antivirals to keep on hand for future cold sores. she can use either 1 day famvir, 1 day valtrex or 2 day acyclovir to treat cold sores. acyclovir is the cheapest option - 800mg 3x/day for 2 days.

Famciclovir ( Famvir ®) is a prescription antiviral medication used to treat the following conditions: Shingles in people with normal immune systems Recurring genital herpes in people with normal immune systems Recurring cold sores in people with normal immune systems

Famciclovir

Shingles Channel Topics & Medications Herpes Zoster Oticus Postherpetic Neuralgia Shingles Acyclovir Famciclovir Gabapentin Gralise Lidoderm Qutenza Valacyclovir Zostavax Advertisement Quicklinks Shingles Causes of Shingles Shingles Rash Symptoms of Shingles Shingles Treatment Shingles and Pregnancy Shingles Pain Cure for Shingles Postherpetic Neuralgia Acyclovir Famciclovir Gabapentin Gabapentin Side Effects Zostavax Lidoderm Patch Related Channels Chickenpox Osteoporosis Pain Senior Health Herpes Advertisement Tweet Shingles Home > Famciclovir Famciclovir Famciclovir is commonly prescribed to treat cold sores, genital herpes, and shingles.

The antiviral medication is typically used at the first signs of an outbreak to help reduce symptoms and prevent outbreaks from occurring again. Depending on the condition being treated, the tablets can be taken every day, for just one day, or for a week.

Side effects may include headaches, vomiting, fatigue, and diarrhea. Interested in a Discount on Famciclovir? Our free Discount Rx savings card can help you and your family save money on your prescriptions. This card is accepted at all major chain pharmacies, nationwide. Enter your name and email address to receive your free savings card. Enter Your Name Enter Your Email Address CLICK HERE to learn more about from e Med TV.com What Is Famciclovir?

Herpes simplex infections (including cold sores and genital herpes) in people with HIV or other conditions that weaken the immune system.

(Click What Is Famciclovir Used For? for more information, including possible off-label uses. )What Should I Tell My Healthcare Provider? You should talk with your healthcare provider prior to taking famciclovir if you have: Kidney disease, including kidney failure (renal failure)Severe lactose intolerance Galactose intolerance Any allergies, including allergies to food, dyes, or preservatives.

Also, let your healthcare provider know if you are: Pregnant or thinking of becoming pregnant (see Famvir and Pregnancy)Breastfeeding (see Famvir and Breastfeeding) .

Make sure to tell your healthcare provider about all other medicines you are currently taking, including prescription and non-prescription medicines, vitamins, and herbal supplements. (Click Precautions and Warnings With Famciclovir to learn more, including information on who should not take the drug.

)Famciclovir Article Continues on Next Page >1 2 3 4 5 Next >>Advertisement7 Tricks to Relieve Your Enlarged Prostate Famciclovir Drug Information Famciclovir Side Effects of Famciclovir What Is Famciclovir Used For?

Famciclovir Dosing Drug Interactions With Famciclovir Precautions and Warnings With Famciclovir Last updated/reviewed: January 25, 2017List of references (click here)Written by/reviewed by: Kristi Monson, Pharm D; Arthur Schoenstadt, MDLast reviewed by: Kristi Monson, Pharm DFamciclovir Drug Information Famciclovir Side Effects of Famciclovir What Is Famciclovir Used For? Famciclovir Dosing Drug Interactions With Famciclovir Precautions and Warnings With Famciclovir Advertisement

Hello. I have recurrent cold sores and have a Famvir prescription for this. Two weeks ago, I felt and saw redness, lumpiness and then a whitish sore that I associate with cold sores and hurriedly bolted down 1500mg of Famvir. But the sore/lesion seems to have been on the inside of my lip (the moist inner mouth), and not on my skin.

Famvir no prescription

"Famvir no prescript

ion Common Questions and Answers about Famvir no prescriptionfamvir My doctor gave me a prescription for famvir, which I was able to start taking approx 30 hours after being infected...already had a significant patch of little white dots. It was the first one had every had (I know because I became very ill with a fever and night sweats etc a couple of days later).

The white dots became several white patches from one corner of my mouth to the other mostly on the part of the lip that isn't really visible when my mouth is closed. Read More

Stupidly I didn't think of this til later. I think, in my panic, I just went for the meds as the easy solution without thinking. Read More Hello. I have recurrent cold sores and have a Famvir prescription for this. Two weeks ago, I felt and saw redness, lumpiness and then a whitish sore that I associate with cold sores and hurriedly bolted down 1500mg of Famvir.

But the sore/lesion seems to have been on the inside of my lip (the moist inner mouth), and not on my skin. Stupidly I didn't think of this til later. I think, in my panic, I just went for the meds as the easy solution without thinking.

Read More All non-controlled prescription products Eli Lilly and Company (800) 545-6962 Products include: Most all Lilly prescription products and insulins.

Fisons Pharmaceuticals Gastrocon Patient Assistance Program P. O. Box 1766 Rochester, NY 14603-1766 Products include: Gastrocrom capsules Fujisawa (800) 477-6472 Products include: Prograf (708) 317-8636 Products include: Nebu Pent Genentech, Inc. Read More There are no over the counter antiviral meds for herpes.

You would need a prescription for either Valtrex, Acyclovir or Famvir. Read More Ok, so I've been putting up with on again, off again itching for months on my labia, near my vaginal opening. Never ""diagnosed"" with HPV but I did get rid of a suspected wart this past year. Can you have a bacterial infection without discharge?

It drives me CRAZY sometimes, the only thing that calms it is gold bond ointment, which is minty and refreshing but I'd like no itch.

No ""rash"" that I can see, unless I give in and scratch. Read More These are Valtrex/valacyclovir, Famvir /famciclovir, and acyclovir. They require a doctor's prescription . There are also several topicals that you can get over the counter.

2. Is Famvir better than Valtrex? 3. Read More Famvir kills herpes and has no side effects. If the sore is worse, it may be bacterial or som thing other than viral. Check wth your doctor first thing. Dr. Read Morezovirax ointment isn't helpful for herpes recurrences. no need to refill that prescription that's for sure. What herpes testing have you had done so far?

Read More OK what do you think about this. I asked for a prescription on famvir and if he could give me more capsule count and he wouldnt work with me at all. Instead after this he wrote me a prescription for 10 capsules 250 mg which was less than the last time which he game me 12 capsules 500mg. So shouldnt it have worked opposite if i asked for more this time? Shouldnt i have atleast been giving a little more?

what kind of prescriptions do you guys get? Read More Well valtrex is generic now everywhere so it shouldn't be a money issue for most folks if they have decent prescription coverage with their insurance.

Acyclovir is still way cheaper but if you have insurance coverage that makes generics low cost, valtrex is, as of this month, going to be WAY cheaper for you now :) the technicality to the answer to your question is this - only valtrex has been studied for reduction in transmission to a partner.

Read More You can use acyclovir, valtrex or famvir for this. Just keep in mind that the antivirals work best when taken at the very first sign of a potential ob so if you start feeling that tell tale tingle/itch or whatever your prodrome is ( if you have one ) start the meds then. No need to wait until you have a full blown ob - the sooner you can start the meds the faster they work. Some folks can even head off a full blown ob if they start medication early enough. Read Mor

Famvir no prescription

"Famvir no prescript

Hello. I have recurrent cold sores and have a Famvir prescription for this. Two weeks ago, I felt and saw redness, lumpiness and then a whitish sore that I associate with cold sores and hurriedly bolted down 1500mg of Famvir. But the sore/lesion seems to have been on the inside of my lip (the moist inner mouth), and not on my skin.